Antibacterial effects of Musa sp. ethanolic leaf extracts against methicillin-resistant and susceptible Staphylococcus aureus
Plant extracts have been widely used to treat bacterial-related diseases due to the presence of phytochemical compounds in the extracts. Banana plants have antimicrobial, antiulcerogenic and antioxidant properties and have been reported to exhibit antibacterial activity against some of the pathogens...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | South African Journal of Chemical Engineering |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1026918520300561 |
| _version_ | 1831558077254467584 |
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| author | Lalita Ambigai Sivasamugham Virusha Nimalan Geetha Subramaniam |
| author_facet | Lalita Ambigai Sivasamugham Virusha Nimalan Geetha Subramaniam |
| author_sort | Lalita Ambigai Sivasamugham |
| collection | DOAJ |
| description | Plant extracts have been widely used to treat bacterial-related diseases due to the presence of phytochemical compounds in the extracts. Banana plants have antimicrobial, antiulcerogenic and antioxidant properties and have been reported to exhibit antibacterial activity against some of the pathogens causing nosocomial infections. Hence, the aim of this study was to investigate the antibacterial effects of 80% ethanolic leaf extracts of Musa paradisiaca, Musa acuminata and Musa sapientum against methicillin-resistant and susceptible Staphylococcus aureus (MRSA and MSSA). The ethanolic leave extracts was obtained by soxhlet extraction and concentrated using a rotary evaporator before subjecting it to the agar well diffusion assay. Based on the diameter of the zones of inhibition, the ethanolic extracts of M. paradisiaca and M. acuminata at the concentration of 2.86 g/mL and 3.33 g/mL respectively, exhibited similar inhibitory effect (p ≤ 0.05) against the tested bacteria when compared with the positive control, clindamycin. This is most likely due to the presence of phytochemicals such as alkaloids and tannins that inhibited the bacterial growth. No zone of inhibition was detected with the extract of M. sapientum. These findings strongly suggest that the ethanolic leave extracts of Musa paradisiaca and Musa acuminata can be further investigated as effective antibacterial agents against MSSA and MRSA. |
| first_indexed | 2024-12-17T05:03:11Z |
| format | Article |
| id | doaj.art-98cfe8538fa6450fa4de1f63f24fc292 |
| institution | Directory Open Access Journal |
| issn | 1026-9185 |
| language | English |
| last_indexed | 2024-12-17T05:03:11Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | South African Journal of Chemical Engineering |
| spelling | doaj.art-98cfe8538fa6450fa4de1f63f24fc2922022-12-21T22:02:30ZengElsevierSouth African Journal of Chemical Engineering1026-91852021-01-0135107110Antibacterial effects of Musa sp. ethanolic leaf extracts against methicillin-resistant and susceptible Staphylococcus aureusLalita Ambigai Sivasamugham0Virusha Nimalan1Geetha Subramaniam2Corresponding author.; Faculty of Health and Life Sciences, INTI International University, Persiaran Perdana BBN, 71800 Nilai, Negeri Sembilan, MalaysiaFaculty of Health and Life Sciences, INTI International University, Persiaran Perdana BBN, 71800 Nilai, Negeri Sembilan, MalaysiaFaculty of Health and Life Sciences, INTI International University, Persiaran Perdana BBN, 71800 Nilai, Negeri Sembilan, MalaysiaPlant extracts have been widely used to treat bacterial-related diseases due to the presence of phytochemical compounds in the extracts. Banana plants have antimicrobial, antiulcerogenic and antioxidant properties and have been reported to exhibit antibacterial activity against some of the pathogens causing nosocomial infections. Hence, the aim of this study was to investigate the antibacterial effects of 80% ethanolic leaf extracts of Musa paradisiaca, Musa acuminata and Musa sapientum against methicillin-resistant and susceptible Staphylococcus aureus (MRSA and MSSA). The ethanolic leave extracts was obtained by soxhlet extraction and concentrated using a rotary evaporator before subjecting it to the agar well diffusion assay. Based on the diameter of the zones of inhibition, the ethanolic extracts of M. paradisiaca and M. acuminata at the concentration of 2.86 g/mL and 3.33 g/mL respectively, exhibited similar inhibitory effect (p ≤ 0.05) against the tested bacteria when compared with the positive control, clindamycin. This is most likely due to the presence of phytochemicals such as alkaloids and tannins that inhibited the bacterial growth. No zone of inhibition was detected with the extract of M. sapientum. These findings strongly suggest that the ethanolic leave extracts of Musa paradisiaca and Musa acuminata can be further investigated as effective antibacterial agents against MSSA and MRSA.http://www.sciencedirect.com/science/article/pii/S1026918520300561Musa paradisiacaMusa acuminataLeaf extractsZone of inhibitionAntibacterial agentsMRSA |
| spellingShingle | Lalita Ambigai Sivasamugham Virusha Nimalan Geetha Subramaniam Antibacterial effects of Musa sp. ethanolic leaf extracts against methicillin-resistant and susceptible Staphylococcus aureus South African Journal of Chemical Engineering Musa paradisiaca Musa acuminata Leaf extracts Zone of inhibition Antibacterial agents MRSA |
| title | Antibacterial effects of Musa sp. ethanolic leaf extracts against methicillin-resistant and susceptible Staphylococcus aureus |
| title_full | Antibacterial effects of Musa sp. ethanolic leaf extracts against methicillin-resistant and susceptible Staphylococcus aureus |
| title_fullStr | Antibacterial effects of Musa sp. ethanolic leaf extracts against methicillin-resistant and susceptible Staphylococcus aureus |
| title_full_unstemmed | Antibacterial effects of Musa sp. ethanolic leaf extracts against methicillin-resistant and susceptible Staphylococcus aureus |
| title_short | Antibacterial effects of Musa sp. ethanolic leaf extracts against methicillin-resistant and susceptible Staphylococcus aureus |
| title_sort | antibacterial effects of musa sp ethanolic leaf extracts against methicillin resistant and susceptible staphylococcus aureus |
| topic | Musa paradisiaca Musa acuminata Leaf extracts Zone of inhibition Antibacterial agents MRSA |
| url | http://www.sciencedirect.com/science/article/pii/S1026918520300561 |
| work_keys_str_mv | AT lalitaambigaisivasamugham antibacterialeffectsofmusaspethanolicleafextractsagainstmethicillinresistantandsusceptiblestaphylococcusaureus AT virushanimalan antibacterialeffectsofmusaspethanolicleafextractsagainstmethicillinresistantandsusceptiblestaphylococcusaureus AT geethasubramaniam antibacterialeffectsofmusaspethanolicleafextractsagainstmethicillinresistantandsusceptiblestaphylococcusaureus |