A novel dual-task paradigm with story recall shows significant differences in the gait kinematics in older adults with cognitive impairment: A cross-sectional study
ObjectiveCognitive and motor dysfunctions in older people become more evident while dual-tasking. Several dual-task paradigms have been used to identify older individuals at the risk of developing Alzheimer’s disease and dementia. This study evaluated gait kinematic parameters for dual-task (DT) con...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Aging Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2022.992873/full |
| _version_ | 1828116120920391680 |
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| author | Nawab Ali Jin Liu Huifang Tian Wei Pan Yao Tang Yao Tang Qian Zhong Yaxin Gao Ming Xiao Ming Xiao Ming Xiao Han Wu Cuiyun Sun Ting Wu Xi Yang Tong Wang Yi Zhu |
| author_facet | Nawab Ali Jin Liu Huifang Tian Wei Pan Yao Tang Yao Tang Qian Zhong Yaxin Gao Ming Xiao Ming Xiao Ming Xiao Han Wu Cuiyun Sun Ting Wu Xi Yang Tong Wang Yi Zhu |
| author_sort | Nawab Ali |
| collection | DOAJ |
| description | ObjectiveCognitive and motor dysfunctions in older people become more evident while dual-tasking. Several dual-task paradigms have been used to identify older individuals at the risk of developing Alzheimer’s disease and dementia. This study evaluated gait kinematic parameters for dual-task (DT) conditions in older adults with mild cognitive impairment (MCI), subjective cognitive decline (SCD), and normal cognition (NC).MethodThis is a cross-sectional, clinical-based study carried out at the Zhongshan Rehabilitation Branch of First Affiliated Hospital of Nanjing Medical University, China.ParticipantsWe recruited 83 community-dwelling participants and sorted them into MCI (n = 24), SCD (n = 33), and NC (n = 26) groups based on neuropsychological tests. Their mean age was 72.0 (5.55) years, and male–female ratio was 42/41 (p = 0.112). Each participant performed one single-task walk and four DT walks: DT calculation with subtracting serial sevens; DT naming animals; DT story recall; and DT words recall.Outcome and measuresKinematic gait parameters of speed, knee peak extension angle, and dual-task cost (DTC) were obtained using the Vicon Nexus motion capture system and calculated by Visual 3D software. A mixed-effect linear regression model was used to analyze the data.ResultsThe difference in gait speed under DT story recall and DT calculation was −0.099 m/s and − 0.119 m/s (p = 0.04, p = 0.013) between MCI and SCD, respectively. Knee peak extension angle under DT story recall, words recall, and single task was bigger in the MCI group compared to the NC group, respectively (p = 0.001, p = 0.001, p = 0.004). DTC was higher in the DT story recall test than all other DT conditions (p < 0.001).ConclusionKinematic gait parameters of knee peak extension angle for the DT story recall were found to be sensitive enough to discriminate MCI individuals from NC group. DTC under DT story recall was higher than the other DT conditions. |
| first_indexed | 2024-04-11T12:50:50Z |
| format | Article |
| id | doaj.art-98d590d45d16480dbeb6b3405ce8f6ad |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-04-11T12:50:50Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-98d590d45d16480dbeb6b3405ce8f6ad2022-12-22T04:23:12ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652022-12-011410.3389/fnagi.2022.992873992873A novel dual-task paradigm with story recall shows significant differences in the gait kinematics in older adults with cognitive impairment: A cross-sectional studyNawab Ali0Jin Liu1Huifang Tian2Wei Pan3Yao Tang4Yao Tang5Qian Zhong6Yaxin Gao7Ming Xiao8Ming Xiao9Ming Xiao10Han Wu11Cuiyun Sun12Ting Wu13Xi Yang14Tong Wang15Yi Zhu16Rehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaClinical Medicine Research Institution, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, ChinaSchool of Rehabilitation Medicine, Nanjing Medical University, Nanjing, ChinaRehabilitation Department, Daishan Community Health Service Center, Nanjing, ChinaSchool of Rehabilitation Medicine, Nanjing Medical University, Nanjing, ChinaRehabilitation Medicine Department, Geriatric Hospital of Nanjing Medical University, Nanjing, ChinaDepartment of Rehabilitation, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of Rehabilitation, Suzhou Municipal Hospital, Gusu School, The Affiliated Suzhou Hospital of Nanjing Medical University, Nanjing Medical University, Suzhou, ChinaJiangsu Key Laboratory of Neurodegeneration, Center for Global Health, Nanjing Medical University, Nanjing, ChinaBrain Institute, The Affiliated Nanjing Brain Hospital of Nanjing Medical University, Nanjing, China0Center of Global Health, Nanjing Medical University, Nanjing, ChinaDepartment of Rehabilitation, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of Rehabilitation, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China1Neurology Department, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaSchool of Rehabilitation Medicine, Nanjing Medical University, Nanjing, ChinaRehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaRehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaObjectiveCognitive and motor dysfunctions in older people become more evident while dual-tasking. Several dual-task paradigms have been used to identify older individuals at the risk of developing Alzheimer’s disease and dementia. This study evaluated gait kinematic parameters for dual-task (DT) conditions in older adults with mild cognitive impairment (MCI), subjective cognitive decline (SCD), and normal cognition (NC).MethodThis is a cross-sectional, clinical-based study carried out at the Zhongshan Rehabilitation Branch of First Affiliated Hospital of Nanjing Medical University, China.ParticipantsWe recruited 83 community-dwelling participants and sorted them into MCI (n = 24), SCD (n = 33), and NC (n = 26) groups based on neuropsychological tests. Their mean age was 72.0 (5.55) years, and male–female ratio was 42/41 (p = 0.112). Each participant performed one single-task walk and four DT walks: DT calculation with subtracting serial sevens; DT naming animals; DT story recall; and DT words recall.Outcome and measuresKinematic gait parameters of speed, knee peak extension angle, and dual-task cost (DTC) were obtained using the Vicon Nexus motion capture system and calculated by Visual 3D software. A mixed-effect linear regression model was used to analyze the data.ResultsThe difference in gait speed under DT story recall and DT calculation was −0.099 m/s and − 0.119 m/s (p = 0.04, p = 0.013) between MCI and SCD, respectively. Knee peak extension angle under DT story recall, words recall, and single task was bigger in the MCI group compared to the NC group, respectively (p = 0.001, p = 0.001, p = 0.004). DTC was higher in the DT story recall test than all other DT conditions (p < 0.001).ConclusionKinematic gait parameters of knee peak extension angle for the DT story recall were found to be sensitive enough to discriminate MCI individuals from NC group. DTC under DT story recall was higher than the other DT conditions.https://www.frontiersin.org/articles/10.3389/fnagi.2022.992873/fullmild cognitive impairmentsubjective cognitive declinemotor dysfunctionsdual-taskingkinematicsgait |
| spellingShingle | Nawab Ali Jin Liu Huifang Tian Wei Pan Yao Tang Yao Tang Qian Zhong Yaxin Gao Ming Xiao Ming Xiao Ming Xiao Han Wu Cuiyun Sun Ting Wu Xi Yang Tong Wang Yi Zhu A novel dual-task paradigm with story recall shows significant differences in the gait kinematics in older adults with cognitive impairment: A cross-sectional study Frontiers in Aging Neuroscience mild cognitive impairment subjective cognitive decline motor dysfunctions dual-tasking kinematics gait |
| title | A novel dual-task paradigm with story recall shows significant differences in the gait kinematics in older adults with cognitive impairment: A cross-sectional study |
| title_full | A novel dual-task paradigm with story recall shows significant differences in the gait kinematics in older adults with cognitive impairment: A cross-sectional study |
| title_fullStr | A novel dual-task paradigm with story recall shows significant differences in the gait kinematics in older adults with cognitive impairment: A cross-sectional study |
| title_full_unstemmed | A novel dual-task paradigm with story recall shows significant differences in the gait kinematics in older adults with cognitive impairment: A cross-sectional study |
| title_short | A novel dual-task paradigm with story recall shows significant differences in the gait kinematics in older adults with cognitive impairment: A cross-sectional study |
| title_sort | novel dual task paradigm with story recall shows significant differences in the gait kinematics in older adults with cognitive impairment a cross sectional study |
| topic | mild cognitive impairment subjective cognitive decline motor dysfunctions dual-tasking kinematics gait |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2022.992873/full |
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