EFFICACY AND SAFETY OF TOCILIZUMAB IN CHILDREN WITH SYSTEMIC JUVENILE ARTHRITIS IN CLINICAL PRACTICE
The paper presents the results of a prospective trial of the efficiency and safety of tocilizumab (TCZ) therapy for sys- temic juvenile arthritis. It analyzes the impact of factors, such as age at onset of the disease, its duration at the time of TCZ therapy initiation, the number of systemic manif...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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IMA PRESS LLC
2015-04-01
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| Series: | Научно-практическая ревматология |
| Subjects: | |
| Online Access: | https://rsp.mediar-press.net/rsp/article/view/2077 |
| _version_ | 1797862735534358528 |
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| author | M. I. Kaleda I. P. Nikishina |
| author_facet | M. I. Kaleda I. P. Nikishina |
| author_sort | M. I. Kaleda |
| collection | DOAJ |
| description | The paper presents the results of a prospective trial of the efficiency and safety of tocilizumab (TCZ) therapy for sys- temic juvenile arthritis. It analyzes the impact of factors, such as age at onset of the disease, its duration at the time of TCZ therapy initiation, the number of systemic manifestations, activity of arthritis, and previous experience in using other biological agents, on the efficiency of the therapy. Moreover, the safety of long-term TCZ usage, reasons for dis- continuation of the therapy, its resumption possibilities, and ways of enhancing therapeutic effectiveness are analyzed. |
| first_indexed | 2024-04-09T22:25:23Z |
| format | Article |
| id | doaj.art-98d66b3619a24bfea7d7730979618625 |
| institution | Directory Open Access Journal |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| last_indexed | 2024-04-09T22:25:23Z |
| publishDate | 2015-04-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj.art-98d66b3619a24bfea7d77309796186252023-03-22T13:45:50ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922015-04-0153220421310.14412/1995-4484-2015-204-2131967EFFICACY AND SAFETY OF TOCILIZUMAB IN CHILDREN WITH SYSTEMIC JUVENILE ARTHRITIS IN CLINICAL PRACTICEM. I. Kaleda0I. P. Nikishina1V.A. Nasonova Research Institute of Rheumatology, MoscowV.A. Nasonova Research Institute of Rheumatology, MoscowThe paper presents the results of a prospective trial of the efficiency and safety of tocilizumab (TCZ) therapy for sys- temic juvenile arthritis. It analyzes the impact of factors, such as age at onset of the disease, its duration at the time of TCZ therapy initiation, the number of systemic manifestations, activity of arthritis, and previous experience in using other biological agents, on the efficiency of the therapy. Moreover, the safety of long-term TCZ usage, reasons for dis- continuation of the therapy, its resumption possibilities, and ways of enhancing therapeutic effectiveness are analyzed.https://rsp.mediar-press.net/rsp/article/view/2077systemic juvenile arthritistocilizumabefficacysafety |
| spellingShingle | M. I. Kaleda I. P. Nikishina EFFICACY AND SAFETY OF TOCILIZUMAB IN CHILDREN WITH SYSTEMIC JUVENILE ARTHRITIS IN CLINICAL PRACTICE Научно-практическая ревматология systemic juvenile arthritis tocilizumab efficacy safety |
| title | EFFICACY AND SAFETY OF TOCILIZUMAB IN CHILDREN WITH SYSTEMIC JUVENILE ARTHRITIS IN CLINICAL PRACTICE |
| title_full | EFFICACY AND SAFETY OF TOCILIZUMAB IN CHILDREN WITH SYSTEMIC JUVENILE ARTHRITIS IN CLINICAL PRACTICE |
| title_fullStr | EFFICACY AND SAFETY OF TOCILIZUMAB IN CHILDREN WITH SYSTEMIC JUVENILE ARTHRITIS IN CLINICAL PRACTICE |
| title_full_unstemmed | EFFICACY AND SAFETY OF TOCILIZUMAB IN CHILDREN WITH SYSTEMIC JUVENILE ARTHRITIS IN CLINICAL PRACTICE |
| title_short | EFFICACY AND SAFETY OF TOCILIZUMAB IN CHILDREN WITH SYSTEMIC JUVENILE ARTHRITIS IN CLINICAL PRACTICE |
| title_sort | efficacy and safety of tocilizumab in children with systemic juvenile arthritis in clinical practice |
| topic | systemic juvenile arthritis tocilizumab efficacy safety |
| url | https://rsp.mediar-press.net/rsp/article/view/2077 |
| work_keys_str_mv | AT mikaleda efficacyandsafetyoftocilizumabinchildrenwithsystemicjuvenilearthritisinclinicalpractice AT ipnikishina efficacyandsafetyoftocilizumabinchildrenwithsystemicjuvenilearthritisinclinicalpractice |