Porcine Anti-viral Immunity: How Important Is It?

Pork has become the number one meat consumed worldwide. Meeting the demand for pork has forced the revolution of swine production from traditional husbandry practices that involved a few pigs or small herds to intensive concentration of swine raised in multisite production systems. This dramatic cha...

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Main Authors: Kelly M. Lager, Alexandra C. Buckley
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02258/full
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author Kelly M. Lager
Alexandra C. Buckley
author_facet Kelly M. Lager
Alexandra C. Buckley
author_sort Kelly M. Lager
collection DOAJ
description Pork has become the number one meat consumed worldwide. Meeting the demand for pork has forced the revolution of swine production from traditional husbandry practices that involved a few pigs or small herds to intensive concentration of swine raised in multisite production systems. This dramatic change has made the production of pork very efficient, but it has also changed the ecology of many swine diseases, may encourage the emergence of new diseases, and amplifies the economic impact of swine diseases. Sustained treatment of diseases in livestock production is not feasible making prevention of disease a priority. Prevention of livestock diseases involves eliminating exposure to pathogens and anti-viral strategies to prevent or reduce clinical disease. For some swine diseases, efficacious vaccines can be made, however, for other diseases the host/pathogen relationship is more complex and efficacious vaccines are not available. Given the increasing demand for pork, the development of new approaches to improve swine anti-viral immunity is critical. Rate-limiting steps to improving vaccines are understanding how the pathogen interacts with the host's immune system, any immunopathology resulting from such interactions and how the host's immune system resolves the infection. Solving this puzzle will require sustained research and may require new technologies to battle contemporary diseases now wreaking havoc in swine production systems around the world. This Special Issue will focus on current swine viral diseases that are the most challenging to the global production of pork with contributions focusing on anti-viral immunity.
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spelling doaj.art-98dbd71cbd91405d8c3dd335b1a2e04a2022-12-21T19:32:46ZengFrontiers Media S.A.Frontiers in Immunology1664-32242019-09-011010.3389/fimmu.2019.02258481269Porcine Anti-viral Immunity: How Important Is It?Kelly M. LagerAlexandra C. BuckleyPork has become the number one meat consumed worldwide. Meeting the demand for pork has forced the revolution of swine production from traditional husbandry practices that involved a few pigs or small herds to intensive concentration of swine raised in multisite production systems. This dramatic change has made the production of pork very efficient, but it has also changed the ecology of many swine diseases, may encourage the emergence of new diseases, and amplifies the economic impact of swine diseases. Sustained treatment of diseases in livestock production is not feasible making prevention of disease a priority. Prevention of livestock diseases involves eliminating exposure to pathogens and anti-viral strategies to prevent or reduce clinical disease. For some swine diseases, efficacious vaccines can be made, however, for other diseases the host/pathogen relationship is more complex and efficacious vaccines are not available. Given the increasing demand for pork, the development of new approaches to improve swine anti-viral immunity is critical. Rate-limiting steps to improving vaccines are understanding how the pathogen interacts with the host's immune system, any immunopathology resulting from such interactions and how the host's immune system resolves the infection. Solving this puzzle will require sustained research and may require new technologies to battle contemporary diseases now wreaking havoc in swine production systems around the world. This Special Issue will focus on current swine viral diseases that are the most challenging to the global production of pork with contributions focusing on anti-viral immunity.https://www.frontiersin.org/article/10.3389/fimmu.2019.02258/fullswinevirusdiseaseimmunologyvaccine
spellingShingle Kelly M. Lager
Alexandra C. Buckley
Porcine Anti-viral Immunity: How Important Is It?
Frontiers in Immunology
swine
virus
disease
immunology
vaccine
title Porcine Anti-viral Immunity: How Important Is It?
title_full Porcine Anti-viral Immunity: How Important Is It?
title_fullStr Porcine Anti-viral Immunity: How Important Is It?
title_full_unstemmed Porcine Anti-viral Immunity: How Important Is It?
title_short Porcine Anti-viral Immunity: How Important Is It?
title_sort porcine anti viral immunity how important is it
topic swine
virus
disease
immunology
vaccine
url https://www.frontiersin.org/article/10.3389/fimmu.2019.02258/full
work_keys_str_mv AT kellymlager porcineantiviralimmunityhowimportantisit
AT alexandracbuckley porcineantiviralimmunityhowimportantisit