Therapeutic targeting of the inflammasome in myeloid malignancies
Abstract Even though genetic perturbations and mutations are important for the development of myeloid malignancies, the effects of an inflammatory microenvironment are a critical modulator of carcinogenesis. Activation of the innate immune system through various ligands and signaling pathways is an...
Main Authors: | Samarpana Chakraborty, Lauren C. Shapiro, Sofia de Oliveira, Bianca Rivera-Pena, Amit Verma, Aditi Shastri |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-09-01
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Series: | Blood Cancer Journal |
Online Access: | https://doi.org/10.1038/s41408-021-00547-8 |
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