Bacterial filamentation as a mechanism for cell-to-cell spread within an animal host
Some intracellular pathogens can directly invade neighboring host cells in cell culture, but it is unclear how this happens in vivo. Here, Tran et al. describe an intracellular bacterium that forms filaments to spread between intestinal epithelial cells in its host nematode, in a process regulated b...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-28297-6 |
| _version_ | 1818486357892268032 |
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| author | Tuan D. Tran Munira Aman Ali Davin Lee Marie-Anne Félix Robert J. Luallen |
| author_facet | Tuan D. Tran Munira Aman Ali Davin Lee Marie-Anne Félix Robert J. Luallen |
| author_sort | Tuan D. Tran |
| collection | DOAJ |
| description | Some intracellular pathogens can directly invade neighboring host cells in cell culture, but it is unclear how this happens in vivo. Here, Tran et al. describe an intracellular bacterium that forms filaments to spread between intestinal epithelial cells in its host nematode, in a process regulated by a conserved nutrient-sensing pathway. |
| first_indexed | 2024-12-10T16:21:52Z |
| format | Article |
| id | doaj.art-98ddd6cea8c644a899660fd5f977cb88 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-10T16:21:52Z |
| publishDate | 2022-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-98ddd6cea8c644a899660fd5f977cb882022-12-22T01:41:47ZengNature PortfolioNature Communications2041-17232022-02-0113111110.1038/s41467-022-28297-6Bacterial filamentation as a mechanism for cell-to-cell spread within an animal hostTuan D. Tran0Munira Aman Ali1Davin Lee2Marie-Anne Félix3Robert J. Luallen4Department of Biology, San Diego State UniversityDepartment of Biology, San Diego State UniversityDepartment of Biology, San Diego State UniversityInstitut de Biologie de l’ École Normale Supérieure, Centre National de la Recherche Scientifique, INSERM, École Normale Supérieure, Paris Sciences et LettresDepartment of Biology, San Diego State UniversitySome intracellular pathogens can directly invade neighboring host cells in cell culture, but it is unclear how this happens in vivo. Here, Tran et al. describe an intracellular bacterium that forms filaments to spread between intestinal epithelial cells in its host nematode, in a process regulated by a conserved nutrient-sensing pathway.https://doi.org/10.1038/s41467-022-28297-6 |
| spellingShingle | Tuan D. Tran Munira Aman Ali Davin Lee Marie-Anne Félix Robert J. Luallen Bacterial filamentation as a mechanism for cell-to-cell spread within an animal host Nature Communications |
| title | Bacterial filamentation as a mechanism for cell-to-cell spread within an animal host |
| title_full | Bacterial filamentation as a mechanism for cell-to-cell spread within an animal host |
| title_fullStr | Bacterial filamentation as a mechanism for cell-to-cell spread within an animal host |
| title_full_unstemmed | Bacterial filamentation as a mechanism for cell-to-cell spread within an animal host |
| title_short | Bacterial filamentation as a mechanism for cell-to-cell spread within an animal host |
| title_sort | bacterial filamentation as a mechanism for cell to cell spread within an animal host |
| url | https://doi.org/10.1038/s41467-022-28297-6 |
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