Inflammasome Activation Contributes to Interleukin-23 Production in Response to <named-content content-type="genus-species">Clostridium difficile</named-content>

Inflammasome Activation Contributes to Interleukin-23 Production in Response to <named-content content-type="genus-species">Clostridium difficile</named-content>

ABSTRACT Clostridium difficile is the most common hospital-acquired pathogen, causing antibiotic-associated diarrhea in over 250,000 patients annually in the United States. Disease is primarily mediated by toxins A and B, which induce potent proinflammatory signaling in host cells and can activate...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs:	Carrie A. Cowardin, Sarah A. Kuehne, Erica L. Buonomo, Chelsea S. Marie, Nigel P. Minton, William A. Petri
Formaat:	Artikel
Taal:	English
Gepubliceerd in:	American Society for Microbiology 2015-02-01
Reeks:	mBio
Online toegang:	https://journals.asm.org/doi/10.1128/mBio.02386-14

Gelijkaardige items

Bone Marrow Dendritic Cells from Mice with an Altered Microbiota Provide Interleukin 17A-Dependent Protection against <named-content content-type="genus-species">Entamoeba histolytica</named-content> Colitis
door: Stacey L. Burgess, et al.
Gepubliceerd in: (2014-12-01)

Function of the CRISPR-Cas System of the Human Pathogen <named-content content-type="genus-species">Clostridium difficile</named-content>
door: Pierre Boudry, et al.
Gepubliceerd in: (2015-10-01)

Structural Characterization of <named-content content-type="genus-species">Clostridium sordellii</named-content> Spores of Diverse Human, Animal, and Environmental Origin and Comparison to <named-content content-type="genus-species">Clostridium difficile</named-content> Spores
door: Rebecca Rabi, et al.
Gepubliceerd in: (2017-10-01)

Toxin Synthesis by <named-content content-type="genus-species">Clostridium difficile</named-content> Is Regulated through Quorum Signaling
door: Charles Darkoh, et al.
Gepubliceerd in: (2015-05-01)

The Gut Microbiota Is Associated with Clearance of <named-content content-type="genus-species">Clostridium difficile</named-content> Infection Independent of Adaptive Immunity
door: Jhansi L. Leslie, et al.
Gepubliceerd in: (2019-02-01)

Germinant Synergy Facilitates <named-content content-type="genus-species">Clostridium difficile</named-content> Spore Germination under Physiological Conditions
door: Travis J. Kochan, et al.
Gepubliceerd in: (2018-10-01)

Accessory Gene Regulator-1 Locus Is Essential for Virulence and Pathogenesis of <named-content content-type="genus-species">Clostridium difficile</named-content>
door: Charles Darkoh, et al.
Gepubliceerd in: (2016-09-01)

Dipicolinic Acid Release by Germinating <named-content content-type="genus-species">Clostridium difficile</named-content> Spores Occurs through a Mechanosensing Mechanism
door: Michael B. Francis, et al.
Gepubliceerd in: (2016-12-01)

Immune Profiling To Predict Outcome of <named-content content-type="genus-species">Clostridioides difficile</named-content> Infection
door: Mayuresh M. Abhyankar, et al.
Gepubliceerd in: (2020-06-01)

Active and Secretory IgA-Coated Bacterial Fractions Elucidate Dysbiosis in <named-content content-type="genus-species">Clostridium difficile</named-content> Infection
door: Mária Džunková, et al.
Gepubliceerd in: (2016-06-01)

Shifts in the Gut Metabolome and <named-content content-type="genus-species">Clostridium difficile</named-content> Transcriptome throughout Colonization and Infection in a Mouse Model
door: Joshua R. Fletcher, et al.
Gepubliceerd in: (2018-04-01)

Minimalistic Cellulosome of the Butanologenic Bacterium <named-content content-type="genus-species">Clostridium saccharoperbutylacetonicum</named-content>
door: Bosmat Levi Hevroni, et al.
Gepubliceerd in: (2020-04-01)

Designed Ankyrin Repeat Protein (DARPin) Neutralizers of TcdB from <named-content content-type="genus-species">Clostridium difficile</named-content> Ribotype 027
door: Zeyu Peng, et al.
Gepubliceerd in: (2019-10-01)

Antibiotic-Induced Alterations of the Murine Gut Microbiota and Subsequent Effects on Colonization Resistance against <named-content content-type="genus-species">Clostridium difficile</named-content>
door: Alyxandria M. Schubert, et al.
Gepubliceerd in: (2015-09-01)

<named-content content-type="genus-species">Clostridium difficile</named-content> Binary Toxin CDT Induces Clustering of the Lipolysis-Stimulated Lipoprotein Receptor into Lipid Rafts
door: Panagiotis Papatheodorou, et al.
Gepubliceerd in: (2013-07-01)

Architecture and Self-Assembly of <named-content content-type="genus-species">Clostridium sporogenes</named-content> and <named-content content-type="genus-species">Clostridium botulinum</named-content> Spore Surfaces Illustrate a General Protective Strategy across Spore Formers
door: Thamarai K. Janganan, et al.
Gepubliceerd in: (2020-08-01)

Effect of <italic toggle="yes">tcdR</italic> Mutation on Sporulation in the Epidemic <named-content content-type="genus-species">Clostridium difficile</named-content> Strain R20291
door: Brintha P. Girinathan, et al.
Gepubliceerd in: (2017-02-01)

Durable Long-Term Bacterial Engraftment following Encapsulated Fecal Microbiota Transplantation To Treat <named-content content-type="genus-species">Clostridium difficile</named-content> Infection
door: Christopher Staley, et al.
Gepubliceerd in: (2019-08-01)

Proteolytic Processing and Activation of <named-content content-type="genus-species">Clostridium perfringens</named-content> Epsilon Toxin by Caprine Small Intestinal Contents
door: John C. Freedman, et al.
Gepubliceerd in: (2014-10-01)

Converting Carbon Dioxide to Butyrate with an Engineered Strain of <named-content content-type="genus-species">Clostridium ljungdahlii</named-content>
door: Toshiyuki Ueki, et al.
Gepubliceerd in: (2014-10-01)

Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for <named-content content-type="genus-species">Clostridium difficile</named-content> Spore Germination and Outgrowth in the Large Intestine
door: Casey M. Theriot, et al.
Gepubliceerd in: (2016-02-01)

The Immune Protein Calprotectin Impacts <named-content content-type="genus-species">Clostridioides difficile</named-content> Metabolism through Zinc Limitation
door: Christopher A. Lopez, et al.
Gepubliceerd in: (2019-12-01)

Adaptive Evolution of <named-content content-type="genus-species">Geobacter sulfurreducens</named-content> in Coculture with <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>
door: Lucie Semenec, et al.
Gepubliceerd in: (2020-04-01)

Independent Microevolution Mediated by Mobile Genetic Elements of Individual <named-content content-type="genus-species">Clostridium difficile</named-content> Isolates from Clade 4 Revealed by Whole-Genome Sequencing
door: Yuan Wu, et al.
Gepubliceerd in: (2019-04-01)

The <named-content content-type="genus-species">Clostridioides difficile</named-content> Cysteine-Rich Exosporium Morphogenetic Protein, CdeC, Exhibits Self-Assembly Properties That Lead to Organized Inclusion Bodies in <named-content content-type="genus-species">Escherichia coli</named-content>
door: A. Romero-Rodríguez, et al.
Gepubliceerd in: (2020-12-01)

RstA Is a Major Regulator of <named-content content-type="genus-species">Clostridioides difficile</named-content> Toxin Production and Motility
door: Adrianne N. Edwards, et al.
Gepubliceerd in: (2019-04-01)

Whole-Genome Sequencing of Human Clinical <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Isolates Reveals Misidentification and Misunderstandings of <named-content content-type="genus-species">Klebsiella pneumoniae</named-content>, <named-content content-type="genus-species">Klebsiella variicola</named-content>, and <named-content content-type="genus-species">Klebsiella quasipneumoniae</named-content>
door: S. Wesley Long, et al.
Gepubliceerd in: (2017-08-01)

ADP-Ribosylation of NLRP3 by <named-content content-type="genus-species">Mycoplasma pneumoniae</named-content> CARDS Toxin Regulates Inflammasome Activity
door: Santanu Bose, et al.
Gepubliceerd in: (2014-12-01)

Candidalysin Crucially Contributes to Nlrp3 Inflammasome Activation by <named-content content-type="genus-species">Candida albicans</named-content> Hyphae
door: Ona Rogiers, et al.
Gepubliceerd in: (2019-02-01)

Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during <named-content content-type="genus-species">Clostridium difficile</named-content> Infections
door: Glen P. Carter, et al.
Gepubliceerd in: (2015-07-01)

Identification of Virulence-Associated Properties by Comparative Genome Analysis of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content>, <named-content content-type="genus-species">S. pseudopneumoniae</named-content>, <named-content content-type="genus-species">S. mitis</named-content>, Three <named-content content-type="genus-species">S. oralis</named-content> Subspecies, and <italic toggle="yes">S. infantis</italic>
door: Mogens Kilian, et al.
Gepubliceerd in: (2019-10-01)

Human Claudin-8 and -14 Are Receptors Capable of Conveying the Cytotoxic Effects of <named-content content-type="genus-species">Clostridium perfringens</named-content> Enterotoxin
door: Archana Shrestha, et al.
Gepubliceerd in: (2013-03-01)

<named-content content-type="genus-species">Candida albicans</named-content> Morphogenesis Is Not Required for Macrophage Interleukin 1β Production
door: Melanie Wellington, et al.
Gepubliceerd in: (2013-03-01)

Abundant and Diverse Clustered Regularly Interspaced Short Palindromic Repeat Spacers in <named-content content-type="genus-species">Clostridium difficile</named-content> Strains and Prophages Target Multiple Phage Types within This Pathogen
door: Katherine R. Hargreaves, et al.
Gepubliceerd in: (2014-10-01)

Phage ϕC2 Mediates Transduction of Tn<italic toggle="yes">6215</italic>, Encoding Erythromycin Resistance, between <named-content content-type="genus-species">Clostridium difficile</named-content> Strains
door: Shan Goh, et al.
Gepubliceerd in: (2013-12-01)

A Complex Scenario of Nonsteroidal Anti-inflammatory Drugs Induced Prostaglandin E2 Production and Gut Microbiota Alteration in <named-content content-type="genus-species">Clostridium difficile</named-content>-Infected Mice
door: Maryam Noori, et al.
Gepubliceerd in: (2020-02-01)

<named-content content-type="genus-species">Candida albicans</named-content> Impacts <named-content content-type="genus-species">Staphylococcus aureus</named-content> Alpha-Toxin Production via Extracellular Alkalinization
door: Olivia A. Todd, et al.
Gepubliceerd in: (2019-12-01)

<named-content content-type="genus-species">Clostridium ramosum</named-content> Promotes High-Fat Diet-Induced Obesity in Gnotobiotic Mouse Models
door: Anni Woting, et al.
Gepubliceerd in: (2014-10-01)

Purification and Characterization of Botulinum Neurotoxin FA from a Genetically Modified <named-content content-type="genus-species">Clostridium botulinum</named-content> Strain
door: Sabine Pellett, et al.
Gepubliceerd in: (2016-02-01)

Evidence That VirS Is a Receptor for the Signaling Peptide of the <named-content content-type="genus-species">Clostridium perfringens</named-content> Agr-like Quorum Sensing System
door: Jihong Li, et al.
Gepubliceerd in: (2020-10-01)