Inflammasome Activation Contributes to Interleukin-23 Production in Response to <named-content content-type="genus-species">Clostridium difficile</named-content>
ABSTRACT Clostridium difficile is the most common hospital-acquired pathogen, causing antibiotic-associated diarrhea in over 250,000 patients annually in the United States. Disease is primarily mediated by toxins A and B, which induce potent proinflammatory signaling in host cells and can activate...
Main Authors: | Carrie A. Cowardin, Sarah A. Kuehne, Erica L. Buonomo, Chelsea S. Marie, Nigel P. Minton, William A. Petri |
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格式: | Article |
語言: | English |
出版: |
American Society for Microbiology
2015-02-01
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叢編: | mBio |
在線閱讀: | https://journals.asm.org/doi/10.1128/mBio.02386-14 |
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