Non-adherence to Disease-Modifying Treatments in Patients with Multiple Sclerosis
Background: Multiple Sclerosis (MS) is a debilitating disease of the central nervous system. Usually, long-term MS medications are injected intramuscularly or subcutaneously, making them intolerable for many MS patients. Objectives: In the present study, the rate and the causes of non-adherence to M...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Guilan University of Medical Sciences
2017-08-01
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| Series: | Caspian Journal of Neurological Sciences |
| Subjects: | |
| Online Access: | http://cjns.gums.ac.ir/browse.php?a_code=A-10-32-76&slc_lang=en&sid=1 |
| _version_ | 1819085364735770624 |
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| author | Seyed-Ali Roudbary Shahrokh Yousefzadeh-Chabok Hamid Behzadnia Babak Bakhshayesh-Eghbali Mohamadreza Emamhadi Amirreza Ghayeghran Hamidreza Hatamian Alia Saberi Sasan Andalib |
| author_facet | Seyed-Ali Roudbary Shahrokh Yousefzadeh-Chabok Hamid Behzadnia Babak Bakhshayesh-Eghbali Mohamadreza Emamhadi Amirreza Ghayeghran Hamidreza Hatamian Alia Saberi Sasan Andalib |
| author_sort | Seyed-Ali Roudbary |
| collection | DOAJ |
| description | Background: Multiple Sclerosis (MS) is a debilitating disease of the central nervous system. Usually, long-term MS medications are injected intramuscularly or subcutaneously, making them intolerable for many MS patients.
Objectives: In the present study, the rate and the causes of non-adherence to MS disease-modifying drugs (DMDs) were assessed in patients with MS.
Materials and Methods: Two hundred and three MS patients of Guilan MS Society were interviewed demographic and clinical data of the patients were collected.
Results: Among the 203 patients, 73.9% were female. The mean±SD age of the patients was 32.47±9.15. Non-adherence to DMDs was due to side effects (21.7%) and requests of the families (21.7%) or ineffectiveness (17.4%). Significant association was seen between the non-adherence to DMDs and gender (p=0.015) and relapses (p=0.021).
Conclusion: The evidence from the present study suggests that there is a high rate of non-adherence to DMDs in MS patients in Guilan. |
| first_indexed | 2024-12-21T21:03:11Z |
| format | Article |
| id | doaj.art-98f05d84ccca441fafb318e8a233b22d |
| institution | Directory Open Access Journal |
| issn | 2383-4307 2423-4818 |
| language | English |
| last_indexed | 2024-12-21T21:03:11Z |
| publishDate | 2017-08-01 |
| publisher | Guilan University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Neurological Sciences |
| spelling | doaj.art-98f05d84ccca441fafb318e8a233b22d2022-12-21T18:50:23ZengGuilan University of Medical SciencesCaspian Journal of Neurological Sciences2383-43072423-48182017-08-01310128134Non-adherence to Disease-Modifying Treatments in Patients with Multiple SclerosisSeyed-Ali Roudbary0Shahrokh Yousefzadeh-Chabok1Hamid Behzadnia2Babak Bakhshayesh-Eghbali3Mohamadreza Emamhadi4Amirreza Ghayeghran5Hamidreza Hatamian6Alia Saberi7Sasan Andalib8 Neurology Department, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Neuroscience Research Center, Department of Neurosurgery, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Department of Neurosurgery, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, IranFaculty of Medicine, Mashhad Branch, Islamic Azad University, Mashhad, Iran; neurosurgery95@gmail.com Neuroscience Research Center, Department of Neurology, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Brachial Plexus and Peripheral Nerve Injury Center, Guilan University of Medical Science, Rasht, Iran Neurology Department, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Neurology Department, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Neuroscience Research Center, Department of Neurology, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Neuroscience Research Center, Department of Neurosurgery, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Background: Multiple Sclerosis (MS) is a debilitating disease of the central nervous system. Usually, long-term MS medications are injected intramuscularly or subcutaneously, making them intolerable for many MS patients. Objectives: In the present study, the rate and the causes of non-adherence to MS disease-modifying drugs (DMDs) were assessed in patients with MS. Materials and Methods: Two hundred and three MS patients of Guilan MS Society were interviewed demographic and clinical data of the patients were collected. Results: Among the 203 patients, 73.9% were female. The mean±SD age of the patients was 32.47±9.15. Non-adherence to DMDs was due to side effects (21.7%) and requests of the families (21.7%) or ineffectiveness (17.4%). Significant association was seen between the non-adherence to DMDs and gender (p=0.015) and relapses (p=0.021). Conclusion: The evidence from the present study suggests that there is a high rate of non-adherence to DMDs in MS patients in Guilan.http://cjns.gums.ac.ir/browse.php?a_code=A-10-32-76&slc_lang=en&sid=1Multiple SclerosisMedication Adherence |
| spellingShingle | Seyed-Ali Roudbary Shahrokh Yousefzadeh-Chabok Hamid Behzadnia Babak Bakhshayesh-Eghbali Mohamadreza Emamhadi Amirreza Ghayeghran Hamidreza Hatamian Alia Saberi Sasan Andalib Non-adherence to Disease-Modifying Treatments in Patients with Multiple Sclerosis Caspian Journal of Neurological Sciences Multiple Sclerosis Medication Adherence |
| title | Non-adherence to Disease-Modifying Treatments in Patients with Multiple Sclerosis |
| title_full | Non-adherence to Disease-Modifying Treatments in Patients with Multiple Sclerosis |
| title_fullStr | Non-adherence to Disease-Modifying Treatments in Patients with Multiple Sclerosis |
| title_full_unstemmed | Non-adherence to Disease-Modifying Treatments in Patients with Multiple Sclerosis |
| title_short | Non-adherence to Disease-Modifying Treatments in Patients with Multiple Sclerosis |
| title_sort | non adherence to disease modifying treatments in patients with multiple sclerosis |
| topic | Multiple Sclerosis Medication Adherence |
| url | http://cjns.gums.ac.ir/browse.php?a_code=A-10-32-76&slc_lang=en&sid=1 |
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