Bio-Impedance Measurement Optimization for High-Resolution Carotid Pulse Sensing

Continuous hemodynamic monitoring is important for long-term cardiovascular healthcare, especially in hypertension. The impedance plethysmography (IPG) based carotid pulse sensing is a non-invasive diagnosis technique for measuring pulse signals and further evaluating the arterial conditions of the...

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Main Authors: Ting-Wei Wang, Hsiao-Wei Chu, Lin Chou, Yen-Ling Sung, Yuan-Ta Shih, Po-Chun Hsu, Hao-Min Cheng, Shien-Fong Lin
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/21/5/1600
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author Ting-Wei Wang
Hsiao-Wei Chu
Lin Chou
Yen-Ling Sung
Yuan-Ta Shih
Po-Chun Hsu
Hao-Min Cheng
Shien-Fong Lin
author_facet Ting-Wei Wang
Hsiao-Wei Chu
Lin Chou
Yen-Ling Sung
Yuan-Ta Shih
Po-Chun Hsu
Hao-Min Cheng
Shien-Fong Lin
author_sort Ting-Wei Wang
collection DOAJ
description Continuous hemodynamic monitoring is important for long-term cardiovascular healthcare, especially in hypertension. The impedance plethysmography (IPG) based carotid pulse sensing is a non-invasive diagnosis technique for measuring pulse signals and further evaluating the arterial conditions of the patient such as continuous blood pressure (BP) monitoring. To reach the high-resolution IPG-based carotid pulse detection for cardiovascular applications, this study provides an optimized measurement parameter in response to obvious pulsation from the carotid artery. The influence of the frequency of excitation current, electrode cross-sectional area, electrode arrangements, and physiological site of carotid arteries on IPG measurement resolution was thoroughly investigated for optimized parameters. In this study, the IPG system was implemented and installed on the subject’s neck above the carotid artery to evaluate the measurement parameters. The measurement results within 6 subjects obtained the arterial impedance variation of 2137 mΩ using the optimized measurement conditions, including excitation frequency of 50 kHz, a smaller area of 2 cm<sup>2</sup>, electrode spacing of 4 cm and 1.7 cm for excitation and sensing functions, and location on the left side of the neck. The significance of this study demonstrates an optimized measurement methodology of IPG-based carotid pulse sensing that greatly improves the measurement quality in cardiovascular monitoring.
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spelling doaj.art-98f84308a82b420e936d5e21f7cc016f2023-12-11T18:22:41ZengMDPI AGSensors1424-82202021-02-01215160010.3390/s21051600Bio-Impedance Measurement Optimization for High-Resolution Carotid Pulse SensingTing-Wei Wang0Hsiao-Wei Chu1Lin Chou2Yen-Ling Sung3Yuan-Ta Shih4Po-Chun Hsu5Hao-Min Cheng6Shien-Fong Lin7Institute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu 30010, TaiwanInstitute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu 30010, TaiwanInstitute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu 30010, TaiwanInstitute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu 30010, TaiwanResearch and Development Department VI, Smart Healthcare BU, Leadtek Research Inc., New Taipei 23511, TaiwanResearch and Development Department VI, Smart Healthcare BU, Leadtek Research Inc., New Taipei 23511, TaiwanCenter for Evidence-Based Medicine, Department of Medical Education, Taipei Veterans General Hospital, Taipei 11217, TaiwanInstitute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu 30010, TaiwanContinuous hemodynamic monitoring is important for long-term cardiovascular healthcare, especially in hypertension. The impedance plethysmography (IPG) based carotid pulse sensing is a non-invasive diagnosis technique for measuring pulse signals and further evaluating the arterial conditions of the patient such as continuous blood pressure (BP) monitoring. To reach the high-resolution IPG-based carotid pulse detection for cardiovascular applications, this study provides an optimized measurement parameter in response to obvious pulsation from the carotid artery. The influence of the frequency of excitation current, electrode cross-sectional area, electrode arrangements, and physiological site of carotid arteries on IPG measurement resolution was thoroughly investigated for optimized parameters. In this study, the IPG system was implemented and installed on the subject’s neck above the carotid artery to evaluate the measurement parameters. The measurement results within 6 subjects obtained the arterial impedance variation of 2137 mΩ using the optimized measurement conditions, including excitation frequency of 50 kHz, a smaller area of 2 cm<sup>2</sup>, electrode spacing of 4 cm and 1.7 cm for excitation and sensing functions, and location on the left side of the neck. The significance of this study demonstrates an optimized measurement methodology of IPG-based carotid pulse sensing that greatly improves the measurement quality in cardiovascular monitoring.https://www.mdpi.com/1424-8220/21/5/1600bio-impedance measurementcarotid pulse sensingcardiovascular monitoringcontinuous blood pressurehemodynamicsimpedance plethysmography (IPG)
spellingShingle Ting-Wei Wang
Hsiao-Wei Chu
Lin Chou
Yen-Ling Sung
Yuan-Ta Shih
Po-Chun Hsu
Hao-Min Cheng
Shien-Fong Lin
Bio-Impedance Measurement Optimization for High-Resolution Carotid Pulse Sensing
Sensors
bio-impedance measurement
carotid pulse sensing
cardiovascular monitoring
continuous blood pressure
hemodynamics
impedance plethysmography (IPG)
title Bio-Impedance Measurement Optimization for High-Resolution Carotid Pulse Sensing
title_full Bio-Impedance Measurement Optimization for High-Resolution Carotid Pulse Sensing
title_fullStr Bio-Impedance Measurement Optimization for High-Resolution Carotid Pulse Sensing
title_full_unstemmed Bio-Impedance Measurement Optimization for High-Resolution Carotid Pulse Sensing
title_short Bio-Impedance Measurement Optimization for High-Resolution Carotid Pulse Sensing
title_sort bio impedance measurement optimization for high resolution carotid pulse sensing
topic bio-impedance measurement
carotid pulse sensing
cardiovascular monitoring
continuous blood pressure
hemodynamics
impedance plethysmography (IPG)
url https://www.mdpi.com/1424-8220/21/5/1600
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