Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment
Bacterial keratitis is an acute or chronic, transient or recurrent infection of the cornea with varying predilection for anatomical and topographical parts of the cornea like marginal or central. It is a potentially sight-threatening corneal infection in humans that is generally found in eyes with p...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Sultan Qaboos University
2009-08-01
|
Series: | Sultan Qaboos University Medical Journal |
Subjects: | |
Online Access: | https://journals.squ.edu.om/index.php/squmj/article/view/1428 |
_version_ | 1818206782105845760 |
---|---|
author | Abdullah Al-Mujaini Nadia Al-Kharusi Archana Thakral Upender K Wali |
author_facet | Abdullah Al-Mujaini Nadia Al-Kharusi Archana Thakral Upender K Wali |
author_sort | Abdullah Al-Mujaini |
collection | DOAJ |
description | Bacterial keratitis is an acute or chronic, transient or recurrent infection of the cornea with varying predilection for anatomical and topographical parts of the cornea like marginal or central. It is a potentially sight-threatening corneal infection in humans that is generally found in eyes with predisposing elements, the most common of which is contact lens wear. The epidemiological data reveals the universal occurrence of this disease. With advances in the understanding of its pathogenesis, laboratory investigations like immunohistochemistry, fluorescent microscopy, enzyme immunoassays and molecular biology, and the availability of fourth generation antibiotics, the overall visual outcome in bacterial keratitis has improved with time. Particular attention should be given to this condition as it can progress very rapidly with complete corneal destruction occurring within 24-48 hours. Early diagnosis, which is primarily clinical and substantiated largely by microbiological data, and prompt treatment are needed to minimise the possibility of permanent visual loss and reduce structural damage to the cornea. |
first_indexed | 2024-12-12T04:18:29Z |
format | Article |
id | doaj.art-98fa01079dd249e3881c6289b141d72f |
institution | Directory Open Access Journal |
issn | 2075-051X 2075-0528 |
language | English |
last_indexed | 2024-12-12T04:18:29Z |
publishDate | 2009-08-01 |
publisher | Sultan Qaboos University |
record_format | Article |
series | Sultan Qaboos University Medical Journal |
spelling | doaj.art-98fa01079dd249e3881c6289b141d72f2022-12-22T00:38:24ZengSultan Qaboos UniversitySultan Qaboos University Medical Journal2075-051X2075-05282009-08-01921841951356Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and TreatmentAbdullah Al-Mujaini0Nadia Al-Kharusi1Archana Thakral2Upender K Wali3Department of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Sultanate of OmanDepartment of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Sultanate of OmanDepartment of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Sultanate of OmanDepartment of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Sultanate of OmanBacterial keratitis is an acute or chronic, transient or recurrent infection of the cornea with varying predilection for anatomical and topographical parts of the cornea like marginal or central. It is a potentially sight-threatening corneal infection in humans that is generally found in eyes with predisposing elements, the most common of which is contact lens wear. The epidemiological data reveals the universal occurrence of this disease. With advances in the understanding of its pathogenesis, laboratory investigations like immunohistochemistry, fluorescent microscopy, enzyme immunoassays and molecular biology, and the availability of fourth generation antibiotics, the overall visual outcome in bacterial keratitis has improved with time. Particular attention should be given to this condition as it can progress very rapidly with complete corneal destruction occurring within 24-48 hours. Early diagnosis, which is primarily clinical and substantiated largely by microbiological data, and prompt treatment are needed to minimise the possibility of permanent visual loss and reduce structural damage to the cornea.https://journals.squ.edu.om/index.php/squmj/article/view/1428keratitistoxinscontact lens |
spellingShingle | Abdullah Al-Mujaini Nadia Al-Kharusi Archana Thakral Upender K Wali Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment Sultan Qaboos University Medical Journal keratitis toxins contact lens |
title | Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment |
title_full | Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment |
title_fullStr | Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment |
title_full_unstemmed | Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment |
title_short | Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment |
title_sort | bacterial keratitis perspective on epidemiology clinico pathogenesis diagnosis and treatment |
topic | keratitis toxins contact lens |
url | https://journals.squ.edu.om/index.php/squmj/article/view/1428 |
work_keys_str_mv | AT abdullahalmujaini bacterialkeratitisperspectiveonepidemiologyclinicopathogenesisdiagnosisandtreatment AT nadiaalkharusi bacterialkeratitisperspectiveonepidemiologyclinicopathogenesisdiagnosisandtreatment AT archanathakral bacterialkeratitisperspectiveonepidemiologyclinicopathogenesisdiagnosisandtreatment AT upenderkwali bacterialkeratitisperspectiveonepidemiologyclinicopathogenesisdiagnosisandtreatment |