Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment

Bacterial keratitis is an acute or chronic, transient or recurrent infection of the cornea with varying predilection for anatomical and topographical parts of the cornea like marginal or central. It is a potentially sight-threatening corneal infection in humans that is generally found in eyes with p...

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Main Authors: Abdullah Al-Mujaini, Nadia Al-Kharusi, Archana Thakral, Upender K Wali
Format: Article
Language:English
Published: Sultan Qaboos University 2009-08-01
Series:Sultan Qaboos University Medical Journal
Subjects:
Online Access:https://journals.squ.edu.om/index.php/squmj/article/view/1428
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author Abdullah Al-Mujaini
Nadia Al-Kharusi
Archana Thakral
Upender K Wali
author_facet Abdullah Al-Mujaini
Nadia Al-Kharusi
Archana Thakral
Upender K Wali
author_sort Abdullah Al-Mujaini
collection DOAJ
description Bacterial keratitis is an acute or chronic, transient or recurrent infection of the cornea with varying predilection for anatomical and topographical parts of the cornea like marginal or central. It is a potentially sight-threatening corneal infection in humans that is generally found in eyes with predisposing elements, the most common of which is contact lens wear. The epidemiological data reveals the universal occurrence of this disease. With advances in the understanding of its pathogenesis, laboratory investigations like immunohistochemistry, fluorescent microscopy, enzyme immunoassays and molecular biology, and the availability of fourth generation antibiotics, the overall visual outcome in bacterial keratitis has improved with time. Particular attention should be given to this condition as it can progress very rapidly with complete corneal destruction occurring within 24-48 hours. Early diagnosis, which is primarily clinical and substantiated largely by microbiological data, and prompt treatment are needed to minimise the possibility of permanent visual loss and reduce structural damage to the cornea.
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spelling doaj.art-98fa01079dd249e3881c6289b141d72f2022-12-22T00:38:24ZengSultan Qaboos UniversitySultan Qaboos University Medical Journal2075-051X2075-05282009-08-01921841951356Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and TreatmentAbdullah Al-Mujaini0Nadia Al-Kharusi1Archana Thakral2Upender K Wali3Department of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Sultanate of OmanDepartment of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Sultanate of OmanDepartment of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Sultanate of OmanDepartment of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Sultanate of OmanBacterial keratitis is an acute or chronic, transient or recurrent infection of the cornea with varying predilection for anatomical and topographical parts of the cornea like marginal or central. It is a potentially sight-threatening corneal infection in humans that is generally found in eyes with predisposing elements, the most common of which is contact lens wear. The epidemiological data reveals the universal occurrence of this disease. With advances in the understanding of its pathogenesis, laboratory investigations like immunohistochemistry, fluorescent microscopy, enzyme immunoassays and molecular biology, and the availability of fourth generation antibiotics, the overall visual outcome in bacterial keratitis has improved with time. Particular attention should be given to this condition as it can progress very rapidly with complete corneal destruction occurring within 24-48 hours. Early diagnosis, which is primarily clinical and substantiated largely by microbiological data, and prompt treatment are needed to minimise the possibility of permanent visual loss and reduce structural damage to the cornea.https://journals.squ.edu.om/index.php/squmj/article/view/1428keratitistoxinscontact lens
spellingShingle Abdullah Al-Mujaini
Nadia Al-Kharusi
Archana Thakral
Upender K Wali
Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment
Sultan Qaboos University Medical Journal
keratitis
toxins
contact lens
title Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment
title_full Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment
title_fullStr Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment
title_full_unstemmed Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment
title_short Bacterial Keratitis: Perspective on Epidemiology, Clinico-Pathogenesis, Diagnosis and Treatment
title_sort bacterial keratitis perspective on epidemiology clinico pathogenesis diagnosis and treatment
topic keratitis
toxins
contact lens
url https://journals.squ.edu.om/index.php/squmj/article/view/1428
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AT nadiaalkharusi bacterialkeratitisperspectiveonepidemiologyclinicopathogenesisdiagnosisandtreatment
AT archanathakral bacterialkeratitisperspectiveonepidemiologyclinicopathogenesisdiagnosisandtreatment
AT upenderkwali bacterialkeratitisperspectiveonepidemiologyclinicopathogenesisdiagnosisandtreatment