A Macrophage Membrane–Polymer Hybrid Biomimetic Nanoplatform for Therapeutic Delivery of Somatostatin Peptide to Chronic Pancreatitis

A Macrophage Membrane–Polymer Hybrid Biomimetic Nanoplatform for Therapeutic Delivery of Somatostatin Peptide to Chronic Pancreatitis

The clinical translation of therapeutic peptides is generally challenged by multiple issues involving absorption, distribution, metabolism and excretion. In this study, a macrophage membrane-coated poly(lactic-co-glycolic acid) (PLGA) nanodelivery system was developed to enhance the bioavailability...

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Bibliographic Details
Main Authors:	Fang Wang, Yu Deng, Luying Yu, Ao Zhou, Jieting Wang, Jingyan Jia, Ning Li, Fadian Ding, Wei Lian, Qicai Liu, Yu Yang, Xinhua Lin
Format:	Article
Language:	English
Published:	MDPI AG 2022-10-01
Series:	Pharmaceutics
Subjects:	peptide delivery chronic pancreatitis somatostatin macrophage membrane biomimetic nanoparticles
Online Access:	https://www.mdpi.com/1999-4923/14/11/2341

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