A Unique Robust Dual-Promoter-Driven and Dual-Reporter-Expressing SARS-CoV-2 Replicon: Construction and Characterization

A Unique Robust Dual-Promoter-Driven and Dual-Reporter-Expressing SARS-CoV-2 Replicon: Construction and Characterization

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2, SARS2) remains a great global health threat and demands identification of more effective and SARS2-targeted antiviral drugs, even with successful development of anti-SARS2 vaccines. Viral replicons have proven to be a rapid, safe, and...

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Bibliographic Details
Main Authors: Ying Liu, Lu Li, Khalid A. Timani, Johnny J. He
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Viruses
Subjects:
SARS2
DNA replicon
RNA replicon
dual-promoter-driven
dual-reporter genes
Online Access:https://www.mdpi.com/1999-4915/14/5/974

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