Epidemiology and cost of seasonal influenza in Germany - a claims data analysis

Abstract Background Seasonal influenza contributes substantially to the burden of communicable diseases in Europe, especially among paediatric populations and the elderly. The aim of the present study was to estimate the incidence of seasonal influenza in Germany, the probabilities of related compli...

Full description

Bibliographic Details
Main Authors: Stefan Scholz, Oliver Damm, Udo Schneider, Bernhard Ultsch, Ole Wichmann, Wolfgang Greiner
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Public Health
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12889-019-7458-x
_version_ 1818841332116881408
author Stefan Scholz
Oliver Damm
Udo Schneider
Bernhard Ultsch
Ole Wichmann
Wolfgang Greiner
author_facet Stefan Scholz
Oliver Damm
Udo Schneider
Bernhard Ultsch
Ole Wichmann
Wolfgang Greiner
author_sort Stefan Scholz
collection DOAJ
description Abstract Background Seasonal influenza contributes substantially to the burden of communicable diseases in Europe, especially among paediatric populations and the elderly. The aim of the present study was to estimate the incidence of seasonal influenza in Germany, the probabilities of related complications and the economic burden of influenza per case and on a population level for different age groups. Methods Claims data from 2012 to 2014 from > 8 million insured of a large German sick-ness fund were analysed. A matched case control study was used on a sub-sample of 100,000 influenza cases to calculate complication rates for ear infections/acute otitis media (AOM) and community-acquired pneumonia (CAP) as well as resource use and costs for seven age groups. Results Incidence of seasonal influenza varies between the years and is highest among infants and children 2 to 5 years of age. AOM is more likely in the younger age groups with up to 14% more patients in the influenza group than in the control group. CAP is more frequently observed in the younger age groups and in influenza patients 60 years and older. The manifestation of one influenza complication (AOM or CAP) significantly in-creases the occurrence of a second complication (AOM or CAP). The economic burden per case is highest in infants (€251.91) and persons over 60 years of age (€131.59). Conclusion The burden of influenza is highest among infants and young children, which is also reflected in the economic burden. Influenza related costs per case are nearly double for infants compared to persons over 60 years of age.
first_indexed 2024-12-19T04:24:24Z
format Article
id doaj.art-98fc43e47fe14e16a87254d3a45cef1c
institution Directory Open Access Journal
issn 1471-2458
language English
last_indexed 2024-12-19T04:24:24Z
publishDate 2019-08-01
publisher BMC
record_format Article
series BMC Public Health
spelling doaj.art-98fc43e47fe14e16a87254d3a45cef1c2022-12-21T20:36:03ZengBMCBMC Public Health1471-24582019-08-0119111010.1186/s12889-019-7458-xEpidemiology and cost of seasonal influenza in Germany - a claims data analysisStefan Scholz0Oliver Damm1Udo Schneider2Bernhard Ultsch3Ole Wichmann4Wolfgang Greiner5School of Public Health, Bielefeld UniversitySchool of Public Health, Bielefeld UniversityTechniker Krankenkasse (TK)Immunization Unit, Robert Koch Institute (RKI)Immunization Unit, Robert Koch Institute (RKI)School of Public Health, Bielefeld UniversityAbstract Background Seasonal influenza contributes substantially to the burden of communicable diseases in Europe, especially among paediatric populations and the elderly. The aim of the present study was to estimate the incidence of seasonal influenza in Germany, the probabilities of related complications and the economic burden of influenza per case and on a population level for different age groups. Methods Claims data from 2012 to 2014 from > 8 million insured of a large German sick-ness fund were analysed. A matched case control study was used on a sub-sample of 100,000 influenza cases to calculate complication rates for ear infections/acute otitis media (AOM) and community-acquired pneumonia (CAP) as well as resource use and costs for seven age groups. Results Incidence of seasonal influenza varies between the years and is highest among infants and children 2 to 5 years of age. AOM is more likely in the younger age groups with up to 14% more patients in the influenza group than in the control group. CAP is more frequently observed in the younger age groups and in influenza patients 60 years and older. The manifestation of one influenza complication (AOM or CAP) significantly in-creases the occurrence of a second complication (AOM or CAP). The economic burden per case is highest in infants (€251.91) and persons over 60 years of age (€131.59). Conclusion The burden of influenza is highest among infants and young children, which is also reflected in the economic burden. Influenza related costs per case are nearly double for infants compared to persons over 60 years of age.http://link.springer.com/article/10.1186/s12889-019-7458-xSeasonal influenzaEpidemiologyHealth economicsCost of illnessClaims data
spellingShingle Stefan Scholz
Oliver Damm
Udo Schneider
Bernhard Ultsch
Ole Wichmann
Wolfgang Greiner
Epidemiology and cost of seasonal influenza in Germany - a claims data analysis
BMC Public Health
Seasonal influenza
Epidemiology
Health economics
Cost of illness
Claims data
title Epidemiology and cost of seasonal influenza in Germany - a claims data analysis
title_full Epidemiology and cost of seasonal influenza in Germany - a claims data analysis
title_fullStr Epidemiology and cost of seasonal influenza in Germany - a claims data analysis
title_full_unstemmed Epidemiology and cost of seasonal influenza in Germany - a claims data analysis
title_short Epidemiology and cost of seasonal influenza in Germany - a claims data analysis
title_sort epidemiology and cost of seasonal influenza in germany a claims data analysis
topic Seasonal influenza
Epidemiology
Health economics
Cost of illness
Claims data
url http://link.springer.com/article/10.1186/s12889-019-7458-x
work_keys_str_mv AT stefanscholz epidemiologyandcostofseasonalinfluenzaingermanyaclaimsdataanalysis
AT oliverdamm epidemiologyandcostofseasonalinfluenzaingermanyaclaimsdataanalysis
AT udoschneider epidemiologyandcostofseasonalinfluenzaingermanyaclaimsdataanalysis
AT bernhardultsch epidemiologyandcostofseasonalinfluenzaingermanyaclaimsdataanalysis
AT olewichmann epidemiologyandcostofseasonalinfluenzaingermanyaclaimsdataanalysis
AT wolfganggreiner epidemiologyandcostofseasonalinfluenzaingermanyaclaimsdataanalysis