Urinary Peptide Levels in Patients with Chronic Renal Failure
Introduction: Peptide levels in urine are found to be decreased in renal failure. In the current study urinary peptide levels were determined in chronic renal failure (CRF) patients. Method: 86 CRF patients and 80 healthy controls were selected for the study. Urinary proteins and peptide levels were...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Light House Polyclinic Mangalore
2010-10-01
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| Series: | Online Journal of Health & Allied Sciences |
| Subjects: | |
| Online Access: | http://www.ojhas.org/issue35/2010-3-5.htm |
| _version_ | 1818140822203269120 |
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| author | Mungli Prakash Nagaraj M Phani Kavya R Supriya M |
| author_facet | Mungli Prakash Nagaraj M Phani Kavya R Supriya M |
| author_sort | Mungli Prakash |
| collection | DOAJ |
| description | Introduction: Peptide levels in urine are found to be decreased in renal failure. In the current study urinary peptide levels were determined in chronic renal failure (CRF) patients. Method: 86 CRF patients and 80 healthy controls were selected for the study. Urinary proteins and peptide levels were determined by spectrophotometer based Lowry and Bradford methods. Urinary creatinine levels were determined by clinical chemistry analyzer. Results: There was significant decrease in urinary peptide levels in CRF patients and Urinary % peptides were significantly decreased in CRF patients as compared to healthy controls. Urinary % peptides correlated negatively with proteinuria. Conclusion: we have found decrease in urinary peptides and % urinary peptides in CRF patients and possibly measurement of % urinary peptides may possibly serve as better indicator in early detection of impairment in renal function. |
| first_indexed | 2024-12-11T10:50:05Z |
| format | Article |
| id | doaj.art-98fe20ba5980498188f4b956cba6372b |
| institution | Directory Open Access Journal |
| issn | 0972-5997 |
| language | English |
| last_indexed | 2024-12-11T10:50:05Z |
| publishDate | 2010-10-01 |
| publisher | Light House Polyclinic Mangalore |
| record_format | Article |
| series | Online Journal of Health & Allied Sciences |
| spelling | doaj.art-98fe20ba5980498188f4b956cba6372b2022-12-22T01:10:21ZengLight House Polyclinic MangaloreOnline Journal of Health & Allied Sciences0972-59972010-10-0193Urinary Peptide Levels in Patients with Chronic Renal FailureMungli PrakashNagaraj M PhaniKavya RSupriya MIntroduction: Peptide levels in urine are found to be decreased in renal failure. In the current study urinary peptide levels were determined in chronic renal failure (CRF) patients. Method: 86 CRF patients and 80 healthy controls were selected for the study. Urinary proteins and peptide levels were determined by spectrophotometer based Lowry and Bradford methods. Urinary creatinine levels were determined by clinical chemistry analyzer. Results: There was significant decrease in urinary peptide levels in CRF patients and Urinary % peptides were significantly decreased in CRF patients as compared to healthy controls. Urinary % peptides correlated negatively with proteinuria. Conclusion: we have found decrease in urinary peptides and % urinary peptides in CRF patients and possibly measurement of % urinary peptides may possibly serve as better indicator in early detection of impairment in renal function.http://www.ojhas.org/issue35/2010-3-5.htmPeptiduriaProteinuriaChronic renal failureUrinary peptides |
| spellingShingle | Mungli Prakash Nagaraj M Phani Kavya R Supriya M Urinary Peptide Levels in Patients with Chronic Renal Failure Online Journal of Health & Allied Sciences Peptiduria Proteinuria Chronic renal failure Urinary peptides |
| title | Urinary Peptide Levels in Patients with Chronic Renal Failure |
| title_full | Urinary Peptide Levels in Patients with Chronic Renal Failure |
| title_fullStr | Urinary Peptide Levels in Patients with Chronic Renal Failure |
| title_full_unstemmed | Urinary Peptide Levels in Patients with Chronic Renal Failure |
| title_short | Urinary Peptide Levels in Patients with Chronic Renal Failure |
| title_sort | urinary peptide levels in patients with chronic renal failure |
| topic | Peptiduria Proteinuria Chronic renal failure Urinary peptides |
| url | http://www.ojhas.org/issue35/2010-3-5.htm |
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