Management of intrahepatic splenosis:a case report and review of the literature
Abstract Background Splenosis is the heterotopic autotransplantation and implantation of splenic tissue after splenic trauma or splenectomy. Considering that splenosis often occurs in the mesentery, omentum, and peritoneum, intrahepatic splenosis has seldom been reported. We report a rare case of is...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2018-06-01
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| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12957-018-1419-1 |
| _version_ | 1819265590199582720 |
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| author | Zefeng Xuan Jian Chen Penghong Song Yehui Du Lijun Wang Dalong Wan Shusen Zheng |
| author_facet | Zefeng Xuan Jian Chen Penghong Song Yehui Du Lijun Wang Dalong Wan Shusen Zheng |
| author_sort | Zefeng Xuan |
| collection | DOAJ |
| description | Abstract Background Splenosis is the heterotopic autotransplantation and implantation of splenic tissue after splenic trauma or splenectomy. Considering that splenosis often occurs in the mesentery, omentum, and peritoneum, intrahepatic splenosis has seldom been reported. We report a rare case of isolated intrahepatic splenosis in a 54-year-old man who presented with a liver mass thought to be hepatocellular carcinoma. Case presentation A 54-year-old man was referred to our hospital for further evaluation of a liver lesion. The patient was asymptomatic and had a history of emergent splenectomy after a high-altitude falling accident. Abdominal contrast-enhanced computed tomography revealed a 4.5 × 3.3 cm lesion that was located in segment IV of the left liver lobe. The lesion had an inhomogeneous enhancement during the arterial phase and diminished enhancement during the portal and equilibrium phases. Similar radiological features were also observed on a contrast magnetic resonance imaging scan. Partial hepatectomy was performed with the suspicion of hepatocellular carcinoma. Pathological examination of the liver specimen revealed intrahepatic splenosis. Conclusion Splenosis should be considered in differential diagnosis of a liver mass discovered years after splenic trauma or surgery. A proposed scoring system may be helpful in evaluating the suspicious degree of intrahepatic mass to be splenosis. Invasive treatments are not recommended for asymptomatic patients, since the splenosis can provide beneficial immunologic function. |
| first_indexed | 2024-12-23T20:47:48Z |
| format | Article |
| id | doaj.art-98fee29d353e4268ab786bbf7c7ea9a3 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-12-23T20:47:48Z |
| publishDate | 2018-06-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-98fee29d353e4268ab786bbf7c7ea9a32022-12-21T17:31:44ZengBMCWorld Journal of Surgical Oncology1477-78192018-06-011611810.1186/s12957-018-1419-1Management of intrahepatic splenosis:a case report and review of the literatureZefeng Xuan0Jian Chen1Penghong Song2Yehui Du3Lijun Wang4Dalong Wan5Shusen Zheng6Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang UniversityDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang UniversityDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang UniversityDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Pathology, First Affiliated Hospital, School of Medicine, Zhejiang UniversityDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang UniversityDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang UniversityAbstract Background Splenosis is the heterotopic autotransplantation and implantation of splenic tissue after splenic trauma or splenectomy. Considering that splenosis often occurs in the mesentery, omentum, and peritoneum, intrahepatic splenosis has seldom been reported. We report a rare case of isolated intrahepatic splenosis in a 54-year-old man who presented with a liver mass thought to be hepatocellular carcinoma. Case presentation A 54-year-old man was referred to our hospital for further evaluation of a liver lesion. The patient was asymptomatic and had a history of emergent splenectomy after a high-altitude falling accident. Abdominal contrast-enhanced computed tomography revealed a 4.5 × 3.3 cm lesion that was located in segment IV of the left liver lobe. The lesion had an inhomogeneous enhancement during the arterial phase and diminished enhancement during the portal and equilibrium phases. Similar radiological features were also observed on a contrast magnetic resonance imaging scan. Partial hepatectomy was performed with the suspicion of hepatocellular carcinoma. Pathological examination of the liver specimen revealed intrahepatic splenosis. Conclusion Splenosis should be considered in differential diagnosis of a liver mass discovered years after splenic trauma or surgery. A proposed scoring system may be helpful in evaluating the suspicious degree of intrahepatic mass to be splenosis. Invasive treatments are not recommended for asymptomatic patients, since the splenosis can provide beneficial immunologic function.http://link.springer.com/article/10.1186/s12957-018-1419-1Liver neoplasmIntrahepatic splenosisSplenectomyTrauma |
| spellingShingle | Zefeng Xuan Jian Chen Penghong Song Yehui Du Lijun Wang Dalong Wan Shusen Zheng Management of intrahepatic splenosis:a case report and review of the literature World Journal of Surgical Oncology Liver neoplasm Intrahepatic splenosis Splenectomy Trauma |
| title | Management of intrahepatic splenosis:a case report and review of the literature |
| title_full | Management of intrahepatic splenosis:a case report and review of the literature |
| title_fullStr | Management of intrahepatic splenosis:a case report and review of the literature |
| title_full_unstemmed | Management of intrahepatic splenosis:a case report and review of the literature |
| title_short | Management of intrahepatic splenosis:a case report and review of the literature |
| title_sort | management of intrahepatic splenosis a case report and review of the literature |
| topic | Liver neoplasm Intrahepatic splenosis Splenectomy Trauma |
| url | http://link.springer.com/article/10.1186/s12957-018-1419-1 |
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