Case of hereditary papillary renal cell carcinoma
Renal cell carcinoma is the most common type of renal malignancy and it originates from the renal tubular epithelium. Due to the diversity in the histopathological and molecular characteristics, it is typically subclassified into five different categories. Papillary renal cell carcinoma is one subcl...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Greater Baltimore Medical Center
2012-01-01
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| Series: | Journal of Community Hospital Internal Medicine Perspectives |
| Subjects: | |
| Online Access: | http://www.jchimp.net/index.php/jchimp/article/view/9468/pdf_1 |
| _version_ | 1797966843759034368 |
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| author | Sadaf Mustafa Nima Jadidi Sheila F. Faraj Ronald Rodriguez |
| author_facet | Sadaf Mustafa Nima Jadidi Sheila F. Faraj Ronald Rodriguez |
| author_sort | Sadaf Mustafa |
| collection | DOAJ |
| description | Renal cell carcinoma is the most common type of renal malignancy and it originates from the renal tubular epithelium. Due to the diversity in the histopathological and molecular characteristics, it is typically subclassified into five different categories. Papillary renal cell carcinoma is one subclassification and it includes two variants: sporadic and hereditary. Although the hereditary form comprises a smaller number of cases of papillary renal cell carcinoma, an understanding of the molecular pathways and genetic changes continues to play a significant role in the development of new targeted therapies. Along with recommending appropriate lifestyle modification, further investigation into the molecular pathogenesis of hereditary papillary renal cell carcinoma will continue to be invaluable for the clinical management of renal cell carcinoma. In this article, we discuss a case of the hereditary papillary renal cell carcinoma along with an overview of the disease. |
| first_indexed | 2024-04-11T02:21:46Z |
| format | Article |
| id | doaj.art-990811ae32ae466bac72120a9e397417 |
| institution | Directory Open Access Journal |
| issn | 2000-9666 |
| language | English |
| last_indexed | 2024-04-11T02:21:46Z |
| publishDate | 2012-01-01 |
| publisher | Greater Baltimore Medical Center |
| record_format | Article |
| series | Journal of Community Hospital Internal Medicine Perspectives |
| spelling | doaj.art-990811ae32ae466bac72120a9e3974172023-01-02T23:33:49ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662012-01-01141410.3402/jchimp.v1i4.9468Case of hereditary papillary renal cell carcinomaSadaf MustafaNima JadidiSheila F. FarajRonald RodriguezRenal cell carcinoma is the most common type of renal malignancy and it originates from the renal tubular epithelium. Due to the diversity in the histopathological and molecular characteristics, it is typically subclassified into five different categories. Papillary renal cell carcinoma is one subclassification and it includes two variants: sporadic and hereditary. Although the hereditary form comprises a smaller number of cases of papillary renal cell carcinoma, an understanding of the molecular pathways and genetic changes continues to play a significant role in the development of new targeted therapies. Along with recommending appropriate lifestyle modification, further investigation into the molecular pathogenesis of hereditary papillary renal cell carcinoma will continue to be invaluable for the clinical management of renal cell carcinoma. In this article, we discuss a case of the hereditary papillary renal cell carcinoma along with an overview of the disease.http://www.jchimp.net/index.php/jchimp/article/view/9468/pdf_1familial papillary renal cell carcinomahereditary leiomyomatosis and renal cell carcinomamet proto-oncogenehepatocyte growth factor/scatter factorrenal cancer |
| spellingShingle | Sadaf Mustafa Nima Jadidi Sheila F. Faraj Ronald Rodriguez Case of hereditary papillary renal cell carcinoma Journal of Community Hospital Internal Medicine Perspectives familial papillary renal cell carcinoma hereditary leiomyomatosis and renal cell carcinoma met proto-oncogene hepatocyte growth factor/scatter factor renal cancer |
| title | Case of hereditary papillary renal cell carcinoma |
| title_full | Case of hereditary papillary renal cell carcinoma |
| title_fullStr | Case of hereditary papillary renal cell carcinoma |
| title_full_unstemmed | Case of hereditary papillary renal cell carcinoma |
| title_short | Case of hereditary papillary renal cell carcinoma |
| title_sort | case of hereditary papillary renal cell carcinoma |
| topic | familial papillary renal cell carcinoma hereditary leiomyomatosis and renal cell carcinoma met proto-oncogene hepatocyte growth factor/scatter factor renal cancer |
| url | http://www.jchimp.net/index.php/jchimp/article/view/9468/pdf_1 |
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