Molecular Mechanisms of Memory Consolidation That Operate During Sleep
The role of sleep for brain function has been in the focus of interest for many years. It is now firmly established that sleep and the corresponding brain activity is of central importance for memory consolidation. Less clear are the underlying molecular mechanisms and their specific contribution to...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-11-01
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| Series: | Frontiers in Molecular Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnmol.2021.767384/full |
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| author | Irene Reyes-Resina Sebastian Samer Michael R. Kreutz Michael R. Kreutz Michael R. Kreutz Michael R. Kreutz Anja M. Oelschlegel |
| author_facet | Irene Reyes-Resina Sebastian Samer Michael R. Kreutz Michael R. Kreutz Michael R. Kreutz Michael R. Kreutz Anja M. Oelschlegel |
| author_sort | Irene Reyes-Resina |
| collection | DOAJ |
| description | The role of sleep for brain function has been in the focus of interest for many years. It is now firmly established that sleep and the corresponding brain activity is of central importance for memory consolidation. Less clear are the underlying molecular mechanisms and their specific contribution to the formation of long-term memory. In this review, we summarize the current knowledge of such mechanisms and we discuss the several unknowns that hinder a deeper appreciation of how molecular mechanisms of memory consolidation during sleep impact synaptic function and engram formation. |
| first_indexed | 2024-12-14T14:48:29Z |
| format | Article |
| id | doaj.art-9909f9a4ad37438e81249454e655a576 |
| institution | Directory Open Access Journal |
| issn | 1662-5099 |
| language | English |
| last_indexed | 2024-12-14T14:48:29Z |
| publishDate | 2021-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Molecular Neuroscience |
| spelling | doaj.art-9909f9a4ad37438e81249454e655a5762022-12-21T22:57:13ZengFrontiers Media S.A.Frontiers in Molecular Neuroscience1662-50992021-11-011410.3389/fnmol.2021.767384767384Molecular Mechanisms of Memory Consolidation That Operate During SleepIrene Reyes-Resina0Sebastian Samer1Michael R. Kreutz2Michael R. Kreutz3Michael R. Kreutz4Michael R. Kreutz5Anja M. Oelschlegel6Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, GermanyResearch Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, GermanyResearch Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, GermanyLeibniz Group ’Dendritic Organelles and Synaptic Function’, Center for Molecular Neurobiology, ZMNH, University Medical Center Hamburg-Eppendorf, Hamburg, GermanyCenter for Behavioral Brain Sciences, Otto von Guericke University, Magdeburg, GermanyGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, GermanyResearch Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, GermanyThe role of sleep for brain function has been in the focus of interest for many years. It is now firmly established that sleep and the corresponding brain activity is of central importance for memory consolidation. Less clear are the underlying molecular mechanisms and their specific contribution to the formation of long-term memory. In this review, we summarize the current knowledge of such mechanisms and we discuss the several unknowns that hinder a deeper appreciation of how molecular mechanisms of memory consolidation during sleep impact synaptic function and engram formation.https://www.frontiersin.org/articles/10.3389/fnmol.2021.767384/fullsleepmemory consolidationsynaptic plasticitysynaptic scalingimmediate early genes |
| spellingShingle | Irene Reyes-Resina Sebastian Samer Michael R. Kreutz Michael R. Kreutz Michael R. Kreutz Michael R. Kreutz Anja M. Oelschlegel Molecular Mechanisms of Memory Consolidation That Operate During Sleep Frontiers in Molecular Neuroscience sleep memory consolidation synaptic plasticity synaptic scaling immediate early genes |
| title | Molecular Mechanisms of Memory Consolidation That Operate During Sleep |
| title_full | Molecular Mechanisms of Memory Consolidation That Operate During Sleep |
| title_fullStr | Molecular Mechanisms of Memory Consolidation That Operate During Sleep |
| title_full_unstemmed | Molecular Mechanisms of Memory Consolidation That Operate During Sleep |
| title_short | Molecular Mechanisms of Memory Consolidation That Operate During Sleep |
| title_sort | molecular mechanisms of memory consolidation that operate during sleep |
| topic | sleep memory consolidation synaptic plasticity synaptic scaling immediate early genes |
| url | https://www.frontiersin.org/articles/10.3389/fnmol.2021.767384/full |
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