Peptide Nanoparticle-Mediated Combinatorial Delivery of Cancer-Related siRNAs for Synergistic Anti-Proliferative Activity in Triple Negative Breast Cancer Cells

Peptide Nanoparticle-Mediated Combinatorial Delivery of Cancer-Related siRNAs for Synergistic Anti-Proliferative Activity in Triple Negative Breast Cancer Cells

Triple negative breast cancer (TNBC) is one of the deadliest types of cancer for women of different age groups. Frequently this cancer does not respond to conservative treatment. Combinatorial RNAi can be suggested as an advanced approach to TNBC therapy. Due to the fact that TNBC cells overexpress...

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Bibliographic Details
Main Authors: Anna Egorova, Ivan Pyankov, Marianna Maretina, Vladislav Baranov, Anton Kiselev
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceuticals
Subjects:
triple negative breast cancer
RNAi
peptide nanoparticles
AQP3
CDC20
COL4A2
Online Access:https://www.mdpi.com/1424-8247/14/10/957

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