Auditory Brainstem Responses in Tinnitus: A Review of Who, How, and What?
The auditory brainstem response (ABR) in tinnitus subjects has been extensively investigated over the last decade with the hopes of finding possible abnormalities related to the pathology. Despite this effort, the use of the ABR for tinnitus diagnosis or as an outcome measure is under debate. The pr...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2017-07-01
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| Series: | Frontiers in Aging Neuroscience |
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| Online Access: | http://journal.frontiersin.org/article/10.3389/fnagi.2017.00237/full |
| _version_ | 1818681997707444224 |
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| author | Victoria Milloy Philippe Fournier Daniel Benoit Arnaud Noreña Amineh Koravand |
| author_facet | Victoria Milloy Philippe Fournier Daniel Benoit Arnaud Noreña Amineh Koravand |
| author_sort | Victoria Milloy |
| collection | DOAJ |
| description | The auditory brainstem response (ABR) in tinnitus subjects has been extensively investigated over the last decade with the hopes of finding possible abnormalities related to the pathology. Despite this effort, the use of the ABR for tinnitus diagnosis or as an outcome measure is under debate. The present study reviewed published literature on ABR and tinnitus. The authors searched PubMed, MedLine, Embase, PsycINFO, and CINAHL, and identified additional records through manually searching reference lists and gray literature. There were 4,566 articles identified through database searching and 151 additional studies through the manual search (4,717 total): 2,128 articles were removed as duplicates, and 2,567 records did not meet eligibility criteria. From the final 22 articles that were included, ABR results from 1,240 tinnitus subjects and 664 control subjects were compiled and summarized with a focus on three main areas: the participant characteristics, the methodology used, and the outcome measures of amplitude and/or latency of waves I, III, and V. The results indicate a high level of heterogeneity between the studies for all the assessed areas. Amplitude and latency differences between tinnitus and controls were not consistent between studies. Nevertheless, the longer latency and reduced amplitude of wave I for the tinnitus group with normal hearing compared to matched controls was the most consistent finding across studies. These results support the need for greater stratification of the tinnitus population and the importance of a standardized ABR method to make comparisons between studies possible. |
| first_indexed | 2024-12-17T10:11:50Z |
| format | Article |
| id | doaj.art-990d244197ba4d5eb8d3aab97cbb3563 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-12-17T10:11:50Z |
| publishDate | 2017-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-990d244197ba4d5eb8d3aab97cbb35632022-12-21T21:53:01ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652017-07-01910.3389/fnagi.2017.00237250681Auditory Brainstem Responses in Tinnitus: A Review of Who, How, and What?Victoria Milloy0Philippe Fournier1Daniel Benoit2Arnaud Noreña3Amineh Koravand4School of Rehabilitation Sciences, University of OttawaOttawa, ON, CanadaCentre National de la Recherche Scientifique, Aix-Marseille UniversityMarseille, FranceSchool of Rehabilitation Sciences, University of OttawaOttawa, ON, CanadaCentre National de la Recherche Scientifique, Aix-Marseille UniversityMarseille, FranceSchool of Rehabilitation Sciences, University of OttawaOttawa, ON, CanadaThe auditory brainstem response (ABR) in tinnitus subjects has been extensively investigated over the last decade with the hopes of finding possible abnormalities related to the pathology. Despite this effort, the use of the ABR for tinnitus diagnosis or as an outcome measure is under debate. The present study reviewed published literature on ABR and tinnitus. The authors searched PubMed, MedLine, Embase, PsycINFO, and CINAHL, and identified additional records through manually searching reference lists and gray literature. There were 4,566 articles identified through database searching and 151 additional studies through the manual search (4,717 total): 2,128 articles were removed as duplicates, and 2,567 records did not meet eligibility criteria. From the final 22 articles that were included, ABR results from 1,240 tinnitus subjects and 664 control subjects were compiled and summarized with a focus on three main areas: the participant characteristics, the methodology used, and the outcome measures of amplitude and/or latency of waves I, III, and V. The results indicate a high level of heterogeneity between the studies for all the assessed areas. Amplitude and latency differences between tinnitus and controls were not consistent between studies. Nevertheless, the longer latency and reduced amplitude of wave I for the tinnitus group with normal hearing compared to matched controls was the most consistent finding across studies. These results support the need for greater stratification of the tinnitus population and the importance of a standardized ABR method to make comparisons between studies possible.http://journal.frontiersin.org/article/10.3389/fnagi.2017.00237/fulltinnitusABRreviewbrainstemsynaptopathymeta-analysis |
| spellingShingle | Victoria Milloy Philippe Fournier Daniel Benoit Arnaud Noreña Amineh Koravand Auditory Brainstem Responses in Tinnitus: A Review of Who, How, and What? Frontiers in Aging Neuroscience tinnitus ABR review brainstem synaptopathy meta-analysis |
| title | Auditory Brainstem Responses in Tinnitus: A Review of Who, How, and What? |
| title_full | Auditory Brainstem Responses in Tinnitus: A Review of Who, How, and What? |
| title_fullStr | Auditory Brainstem Responses in Tinnitus: A Review of Who, How, and What? |
| title_full_unstemmed | Auditory Brainstem Responses in Tinnitus: A Review of Who, How, and What? |
| title_short | Auditory Brainstem Responses in Tinnitus: A Review of Who, How, and What? |
| title_sort | auditory brainstem responses in tinnitus a review of who how and what |
| topic | tinnitus ABR review brainstem synaptopathy meta-analysis |
| url | http://journal.frontiersin.org/article/10.3389/fnagi.2017.00237/full |
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