Withaferin A Suppresses Beta Amyloid in APP Expressing Cells: Studies for Tat and Cocaine Associated Neurological Dysfunctions

Withaferin A Suppresses Beta Amyloid in APP Expressing Cells: Studies for Tat and Cocaine Associated Neurological Dysfunctions

Neurological disorders are the biggest concern globally. Out of ~36 million human immunodeficiency virus (HIV) positive people, about 30%–60% exhibit neurological disorders, including dementia and Alzheimer’s disease (AD) like pathology. In AD or AD like neurological disorders, the pathogenesis is m...

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Bibliographic Details
Main Authors: Sneham Tiwari, Venkata Subba Rao Atluri, Adriana Yndart Arias, Rahul Dev Jayant, Ajeet Kaushik, Jonathan Geiger, Madhavan N. Nair
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
beta amyloid (Aβ)
Withaferin A
HIV-1 Tat
cocaine
neurological disorders
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00291/full

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