The Impact of Intestinal Ultrasound on the Management of Inflammatory Bowel Disease: From Established Facts Toward New Horizons
Intestinal ultrasound (IUS) plays a crucial role as a non-invasive and accurate tool to diagnose and assess inflammatory bowel disease (IBD). The rationale for using IUS in Crohn’s disease (CD), a transmural disease, is widely acknowledged. While the use of IUS in ulcerative colitis (UC), a mucosal...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-05-01
|
| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.898092/full |
| _version_ | 1811250981642436608 |
|---|---|
| author | Olga Maria Nardone Giulio Calabrese Anna Testa Anna Caiazzo Giuseppe Fierro Antonio Rispo Fabiana Castiglione |
| author_facet | Olga Maria Nardone Giulio Calabrese Anna Testa Anna Caiazzo Giuseppe Fierro Antonio Rispo Fabiana Castiglione |
| author_sort | Olga Maria Nardone |
| collection | DOAJ |
| description | Intestinal ultrasound (IUS) plays a crucial role as a non-invasive and accurate tool to diagnose and assess inflammatory bowel disease (IBD). The rationale for using IUS in Crohn’s disease (CD), a transmural disease, is widely acknowledged. While the use of IUS in ulcerative colitis (UC), a mucosal disease, is often underestimated, but, recently, it is increasingly expanding. In the context of a treat-to-target approach, the role of IUS is shifting toward a monitoring tool for predicting response to therapy. Hence, adjusting therapeutic strategies based on IUS response could reduce the burden related to endoscopy and speed the decision process with the ultimate goal to alter the natural course of IBD. Assessment of bowel wall thickness (BWT) is the most reliable IUS measure. However, the development of validated and reproducible sonographic scores to measure disease activity and the identification of parameters of therapeutic response remain relevant issues to implement the daily adoption of IUS in clinical practice. Accordingly, this review focuses on the current literature investigating the impact of IUS on CD with emphasis on the concept of transmural healing (TH) and the main related advantages. We further explore new insights on the role of IUS in UC and its clinical implications. |
| first_indexed | 2024-04-12T16:12:51Z |
| format | Article |
| id | doaj.art-9917c111daa44158b9ce52b22e2ddf74 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-12T16:12:51Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-9917c111daa44158b9ce52b22e2ddf742022-12-22T03:25:51ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-05-01910.3389/fmed.2022.898092898092The Impact of Intestinal Ultrasound on the Management of Inflammatory Bowel Disease: From Established Facts Toward New HorizonsOlga Maria Nardone0Giulio Calabrese1Anna Testa2Anna Caiazzo3Giuseppe Fierro4Antonio Rispo5Fabiana Castiglione6Department of Public Health, University of Naples Federico II, Naples, ItalyDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, ItalyDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, ItalyDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, ItalyDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, ItalyDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, ItalyDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, ItalyIntestinal ultrasound (IUS) plays a crucial role as a non-invasive and accurate tool to diagnose and assess inflammatory bowel disease (IBD). The rationale for using IUS in Crohn’s disease (CD), a transmural disease, is widely acknowledged. While the use of IUS in ulcerative colitis (UC), a mucosal disease, is often underestimated, but, recently, it is increasingly expanding. In the context of a treat-to-target approach, the role of IUS is shifting toward a monitoring tool for predicting response to therapy. Hence, adjusting therapeutic strategies based on IUS response could reduce the burden related to endoscopy and speed the decision process with the ultimate goal to alter the natural course of IBD. Assessment of bowel wall thickness (BWT) is the most reliable IUS measure. However, the development of validated and reproducible sonographic scores to measure disease activity and the identification of parameters of therapeutic response remain relevant issues to implement the daily adoption of IUS in clinical practice. Accordingly, this review focuses on the current literature investigating the impact of IUS on CD with emphasis on the concept of transmural healing (TH) and the main related advantages. We further explore new insights on the role of IUS in UC and its clinical implications.https://www.frontiersin.org/articles/10.3389/fmed.2022.898092/fulltransmural healingtransmural remissionCrohn’s diseaseulcerative colitisnoninvasive monitoringintestinal ultrasound |
| spellingShingle | Olga Maria Nardone Giulio Calabrese Anna Testa Anna Caiazzo Giuseppe Fierro Antonio Rispo Fabiana Castiglione The Impact of Intestinal Ultrasound on the Management of Inflammatory Bowel Disease: From Established Facts Toward New Horizons Frontiers in Medicine transmural healing transmural remission Crohn’s disease ulcerative colitis noninvasive monitoring intestinal ultrasound |
| title | The Impact of Intestinal Ultrasound on the Management of Inflammatory Bowel Disease: From Established Facts Toward New Horizons |
| title_full | The Impact of Intestinal Ultrasound on the Management of Inflammatory Bowel Disease: From Established Facts Toward New Horizons |
| title_fullStr | The Impact of Intestinal Ultrasound on the Management of Inflammatory Bowel Disease: From Established Facts Toward New Horizons |
| title_full_unstemmed | The Impact of Intestinal Ultrasound on the Management of Inflammatory Bowel Disease: From Established Facts Toward New Horizons |
| title_short | The Impact of Intestinal Ultrasound on the Management of Inflammatory Bowel Disease: From Established Facts Toward New Horizons |
| title_sort | impact of intestinal ultrasound on the management of inflammatory bowel disease from established facts toward new horizons |
| topic | transmural healing transmural remission Crohn’s disease ulcerative colitis noninvasive monitoring intestinal ultrasound |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.898092/full |
| work_keys_str_mv | AT olgamarianardone theimpactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons AT giuliocalabrese theimpactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons AT annatesta theimpactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons AT annacaiazzo theimpactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons AT giuseppefierro theimpactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons AT antoniorispo theimpactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons AT fabianacastiglione theimpactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons AT olgamarianardone impactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons AT giuliocalabrese impactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons AT annatesta impactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons AT annacaiazzo impactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons AT giuseppefierro impactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons AT antoniorispo impactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons AT fabianacastiglione impactofintestinalultrasoundonthemanagementofinflammatoryboweldiseasefromestablishedfactstowardnewhorizons |