Positive Clinical Outcomes for Severe Reported Pain Using Robust Non-Addictive Home Electrotherapy—A Case-Series
The North American opioid epidemic has resulted in over 800,000 related premature overdose fatalities since 2000, with the United States leading the world in highest opioid deaths per capita. Despite increased federal funding in recent years, intended to address this crisis, opioid overdose mortalit...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/13/2/336 |
| _version_ | 1797619986140758016 |
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| author | Anish Bajaj David Han Igor Elman Panayotis K. Thanos Catherine A. Dennen Rajendra D. Badgaiyan Abdalla Bowirrat Debmalya Barh Kenneth Blum |
| author_facet | Anish Bajaj David Han Igor Elman Panayotis K. Thanos Catherine A. Dennen Rajendra D. Badgaiyan Abdalla Bowirrat Debmalya Barh Kenneth Blum |
| author_sort | Anish Bajaj |
| collection | DOAJ |
| description | The North American opioid epidemic has resulted in over 800,000 related premature overdose fatalities since 2000, with the United States leading the world in highest opioid deaths per capita. Despite increased federal funding in recent years, intended to address this crisis, opioid overdose mortality has continued to increase. Legally prescribed opioids also chronically induce a problematic reduction in affect. While an ideal analgesic has yet to be developed, some effective multimodal non-opioid pharmacological regimens for acute pain management are being more widely utilized. Some investigators have suggested that a safer and more scientifically sound approach might be to induce “dopamine homeostasis” through non-pharmacological approaches, since opioid use even for acute pain of short duration is now being strongly questioned. There is also increasing evidence suggesting that some more robust forms of electrotherapy could be applied as an effective adjunct to avoid the problems associated with opioids. This 4-patient case-series presents such an approach to treatment of severe pain. All 4 of these chiropractic treatment cases involved a component of knee osteoarthritis, in addition to other reported areas of pain. Each patient engaged in a home recovery strategy using H-Wave<sup>®</sup> device stimulation (HWDS) to address residual extremity issues following treatment of spinal subluxation and other standard treatments. A simple statistical analysis was conducted to determine the change in pain scores (Visual Analogue Scale) of pre and post electrotherapy treatments, resulting in significant reductions in self-reported pain (<i>p</i>-value = 0.0002). Three of the four patients continued using the home therapy device long-term as determined by a post-analysis questionnaire. This small case-series demonstrated notably positive outcomes, suggesting consideration of home use of HWDS for safe, non-pharmacological and non-addictive treatment of severe pain. |
| first_indexed | 2024-03-11T08:34:46Z |
| format | Article |
| id | doaj.art-991cfc7593d14d058d9b3a8e0db2de68 |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-11T08:34:46Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-991cfc7593d14d058d9b3a8e0db2de682023-11-16T21:34:00ZengMDPI AGJournal of Personalized Medicine2075-44262023-02-0113233610.3390/jpm13020336Positive Clinical Outcomes for Severe Reported Pain Using Robust Non-Addictive Home Electrotherapy—A Case-SeriesAnish Bajaj0David Han1Igor Elman2Panayotis K. Thanos3Catherine A. Dennen4Rajendra D. Badgaiyan5Abdalla Bowirrat6Debmalya Barh7Kenneth Blum8School of Chiropractic, Cleveland University Health Sciences, Overland Park, KS 66210, USADepartment of Management Science and Statistics, University of Texas at San Antonio, San Antonio, TX 78249, USACenter for Pain and the Brain (P.A.I.N Group), Department of Anesthesiology, Critical Care & Pain Medicine, Boston Children’s Hospital, Boston, MA 02115, USABehavioral Neuropharmacology and Neuroimaging Laboratory on Addictions, Clinical Research Institute on Addictions, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biosciences, State University of New York at Buffalo, Buffalo, NY 14203, USADepartment of Family Medicine, Jefferson Health Northeast, Philadelphia, PA 19114, USADepartment of Psychiatry, South Texas Veteran Health Care System, Audie L. Murphy Memorial VA Hospital, Long School of Medicine, University of Texas Medical Center, San Antonio, TX 78229, USADepartment of Molecular Biology, Adelson School of Medicine, Ariel University, Ariel 40700, IsraelCentre for Genomics and Applied Gene Technology, Institute of Integrative Omics and Applied Biotechnology, Nonakuri, Purba Medinipur 721172, IndiaThe Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USAThe North American opioid epidemic has resulted in over 800,000 related premature overdose fatalities since 2000, with the United States leading the world in highest opioid deaths per capita. Despite increased federal funding in recent years, intended to address this crisis, opioid overdose mortality has continued to increase. Legally prescribed opioids also chronically induce a problematic reduction in affect. While an ideal analgesic has yet to be developed, some effective multimodal non-opioid pharmacological regimens for acute pain management are being more widely utilized. Some investigators have suggested that a safer and more scientifically sound approach might be to induce “dopamine homeostasis” through non-pharmacological approaches, since opioid use even for acute pain of short duration is now being strongly questioned. There is also increasing evidence suggesting that some more robust forms of electrotherapy could be applied as an effective adjunct to avoid the problems associated with opioids. This 4-patient case-series presents such an approach to treatment of severe pain. All 4 of these chiropractic treatment cases involved a component of knee osteoarthritis, in addition to other reported areas of pain. Each patient engaged in a home recovery strategy using H-Wave<sup>®</sup> device stimulation (HWDS) to address residual extremity issues following treatment of spinal subluxation and other standard treatments. A simple statistical analysis was conducted to determine the change in pain scores (Visual Analogue Scale) of pre and post electrotherapy treatments, resulting in significant reductions in self-reported pain (<i>p</i>-value = 0.0002). Three of the four patients continued using the home therapy device long-term as determined by a post-analysis questionnaire. This small case-series demonstrated notably positive outcomes, suggesting consideration of home use of HWDS for safe, non-pharmacological and non-addictive treatment of severe pain.https://www.mdpi.com/2075-4426/13/2/336electrotherapyH-Wave<sup>®</sup>H-Wave<sup>®</sup> home therapy programreduced painnon-addictive alternativeknee osteoarthritis |
| spellingShingle | Anish Bajaj David Han Igor Elman Panayotis K. Thanos Catherine A. Dennen Rajendra D. Badgaiyan Abdalla Bowirrat Debmalya Barh Kenneth Blum Positive Clinical Outcomes for Severe Reported Pain Using Robust Non-Addictive Home Electrotherapy—A Case-Series Journal of Personalized Medicine electrotherapy H-Wave<sup>®</sup> H-Wave<sup>®</sup> home therapy program reduced pain non-addictive alternative knee osteoarthritis |
| title | Positive Clinical Outcomes for Severe Reported Pain Using Robust Non-Addictive Home Electrotherapy—A Case-Series |
| title_full | Positive Clinical Outcomes for Severe Reported Pain Using Robust Non-Addictive Home Electrotherapy—A Case-Series |
| title_fullStr | Positive Clinical Outcomes for Severe Reported Pain Using Robust Non-Addictive Home Electrotherapy—A Case-Series |
| title_full_unstemmed | Positive Clinical Outcomes for Severe Reported Pain Using Robust Non-Addictive Home Electrotherapy—A Case-Series |
| title_short | Positive Clinical Outcomes for Severe Reported Pain Using Robust Non-Addictive Home Electrotherapy—A Case-Series |
| title_sort | positive clinical outcomes for severe reported pain using robust non addictive home electrotherapy a case series |
| topic | electrotherapy H-Wave<sup>®</sup> H-Wave<sup>®</sup> home therapy program reduced pain non-addictive alternative knee osteoarthritis |
| url | https://www.mdpi.com/2075-4426/13/2/336 |
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