Large-conductance Ca2 +-activated K+ channel β1-subunit maintains the contractile phenotype of vascular smooth muscle cells

Large-conductance Ca2 +-activated K+ channel β1-subunit maintains the contractile phenotype of vascular smooth muscle cells

BackgroundVascular smooth muscle cells (VSMCs) phenotype switching is very important during the pathogenesis and progression of vascular diseases. However, it is not well understood how normal VSMCs maintain the differentiated state. The large-conductance Ca2+-activated K+ (BKCa) channels are widely...

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Bibliographic Details
Main Authors: Meili Wang, Shuanglei Li, Hongshan Liu, Mingyuan Liu, Jin Zhang, Yang Wu, Cangsong Xiao, Haixia Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
vascular smooth muscle cells
phenotype switching
BKCa channel
atherosclerosis
post-injury restenosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.1062695/full

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