Approaches to synthesis of ([1,2,4]triazolo[1,5-c]quinazolin-2-yl)benzoic acids as potential anti-inflammators

Approaches to synthesis of ([1,2,4]triazolo[1,5-c]quinazolin-2-yl)benzoic acids as potential anti-inflammators

Despite their high efficacy NSAIDs have significant side effects due to non-selective inhibition of COX-1 and COX-2. Due to this, medical chemists still pay considerable attention to their design and synthesis, in particular the creation of hybrid molecules that combine in their structure a fragment...

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Bibliographic Details
Main Author:	N. I. Krasovska
Format:	Article
Language:	Ukrainian
Published:	The State Expert Center of the Ministry of Health of Ukraine 2022-06-01
Series:	Фармацевтичний журнал
Subjects:	heterocyclization oxidative cyclization ([1 2 4]triazolo[1 5-c]-quіnazolin-2-yl)benzoic acids dimroth rearrangement spectral characteristics anti-inflammatory activity
Online Access:	https://pharmj.org.ua/index.php/journal/article/view/1294/1212

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