Malignant melanoma of the oral mucosa: report of a case
Oral melanomas are rare tumors corresponding to 0.5% of all the oral malignancies. The hard palate and gingiva are more frequently affected. At the moment of diagnosis they are generally in an advanced stage. We describe a case of a 70 years old male with nodular and pigmented lesion in hard palate...
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| Format: | Article |
| Language: | English |
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Universidad de Antioquia
2007-01-01
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| Series: | Revista Facultad de Odontología Universidad de Antioquia |
| Subjects: | |
| Online Access: | https://revistas.udea.edu.co/index.php/odont/article/view/2765/2227 |
| _version_ | 1818058625336213504 |
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| author | Javier Rendón-Henao Diana Santa-Sáenz Juan David Jiménez-Salazar |
| author_facet | Javier Rendón-Henao Diana Santa-Sáenz Juan David Jiménez-Salazar |
| author_sort | Javier Rendón-Henao |
| collection | DOAJ |
| description | Oral melanomas are rare tumors corresponding to 0.5% of all the oral malignancies. The hard palate and gingiva are more frequently affected. At the moment of diagnosis they are generally in an advanced stage. We describe a case of a 70 years old male with nodular and pigmented lesion in hard palate and other macular pigmented lesions, besides a 2cm cervical nodule. The histo-pathological study showed an extensive infiltration by moderately pleomorphic spindle and epitheliod tumoral cells with melanin pigment in the cytoplasm. Immune-histo-chemical staining was positive to S-100 and HMB-45. Cytology by aspiration of the cervical node was carried out with a fine needle, showing cells with wide cytoplasm and presence of melanin pigment and pleomorphic nuclei. The differential diagnosis includes benign and malign vascular tumors, tumors and cysts of salivary glands, and benign pigmented lesions of the mucosa. |
| first_indexed | 2024-12-10T13:03:36Z |
| format | Article |
| id | doaj.art-992a9df0b89b43a9b1e8680a19166cb9 |
| institution | Directory Open Access Journal |
| issn | 0121-246X 2145-7670 |
| language | English |
| last_indexed | 2024-12-10T13:03:36Z |
| publishDate | 2007-01-01 |
| publisher | Universidad de Antioquia |
| record_format | Article |
| series | Revista Facultad de Odontología Universidad de Antioquia |
| spelling | doaj.art-992a9df0b89b43a9b1e8680a19166cb92022-12-22T01:47:55ZengUniversidad de AntioquiaRevista Facultad de Odontología Universidad de Antioquia0121-246X2145-76702007-01-011829398 Malignant melanoma of the oral mucosa: report of a case Javier Rendón-Henao 0 Diana Santa-Sáenz 1 Juan David Jiménez-Salazar 2 Universidad de Antioquia Universidad de Antioquia Universidad de Antioquia Oral melanomas are rare tumors corresponding to 0.5% of all the oral malignancies. The hard palate and gingiva are more frequently affected. At the moment of diagnosis they are generally in an advanced stage. We describe a case of a 70 years old male with nodular and pigmented lesion in hard palate and other macular pigmented lesions, besides a 2cm cervical nodule. The histo-pathological study showed an extensive infiltration by moderately pleomorphic spindle and epitheliod tumoral cells with melanin pigment in the cytoplasm. Immune-histo-chemical staining was positive to S-100 and HMB-45. Cytology by aspiration of the cervical node was carried out with a fine needle, showing cells with wide cytoplasm and presence of melanin pigment and pleomorphic nuclei. The differential diagnosis includes benign and malign vascular tumors, tumors and cysts of salivary glands, and benign pigmented lesions of the mucosa.https://revistas.udea.edu.co/index.php/odont/article/view/2765/2227malignant melanoma of the oral cavitypigmented lesions of the oral cavityinmune-histo-chemistrys-100hbm-45melanoma de la cavidad orallesiones pigmentadas de la mucosa oralinmunohistoquímicahmb-45 |
| spellingShingle | Javier Rendón-Henao Diana Santa-Sáenz Juan David Jiménez-Salazar Malignant melanoma of the oral mucosa: report of a case Revista Facultad de Odontología Universidad de Antioquia malignant melanoma of the oral cavity pigmented lesions of the oral cavity inmune-histo-chemistry s-100 hbm-45 melanoma de la cavidad oral lesiones pigmentadas de la mucosa oral inmunohistoquímica hmb-45 |
| title | Malignant melanoma of the oral mucosa: report of a case |
| title_full | Malignant melanoma of the oral mucosa: report of a case |
| title_fullStr | Malignant melanoma of the oral mucosa: report of a case |
| title_full_unstemmed | Malignant melanoma of the oral mucosa: report of a case |
| title_short | Malignant melanoma of the oral mucosa: report of a case |
| title_sort | malignant melanoma of the oral mucosa report of a case |
| topic | malignant melanoma of the oral cavity pigmented lesions of the oral cavity inmune-histo-chemistry s-100 hbm-45 melanoma de la cavidad oral lesiones pigmentadas de la mucosa oral inmunohistoquímica hmb-45 |
| url | https://revistas.udea.edu.co/index.php/odont/article/view/2765/2227 |
| work_keys_str_mv | AT javierrendonhenao malignantmelanomaoftheoralmucosareportofacase AT dianasantasaenz malignantmelanomaoftheoralmucosareportofacase AT juandavidjimenezsalazar malignantmelanomaoftheoralmucosareportofacase |