Rnf20 deficiency in adipocyte impairs adipose tissue development and thermogenesis

Rnf20 deficiency in adipocyte impairs adipose tissue development and thermogenesis

Abstract RNF20, an E3 ligase critical for monoubiquitination of histone H2B at lysine 120 (H2Bub), has been implicated in the regulation of various cellar processes; however, its physiological roles in adipocytes remain poorly characterized. Here, we report that the adipocyte-specific knockout of Rn...

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Bibliographic Details
Main Authors: Xiaojuan Liang, Cong Tao, Jianfei Pan, Lilan Zhang, Lulu Liu, Ying Zhao, Yiping Fan, Chunwei Cao, Jiali Liu, Jin Zhang, Sin Man Lam, Guanghou Shui, Wanzhu Jin, Wei Li, Jianguo Zhao, Kui Li, Yanfang Wang
Format: Article
Language:English
Published: Oxford University Press 2020-08-01
Series:Protein & Cell
Subjects:
RNF20
fat loss
adipose tissue development
thermogenesis
Online Access:https://doi.org/10.1007/s13238-020-00770-2

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