Proinflammatory and cytotoxic response to nanoparticles in precision-cut lung slices

Proinflammatory and cytotoxic response to nanoparticles in precision-cut lung slices

Precision-cut lung slices (PCLS) are an established ex vivo alternative to in vivo experiments in pharmacotoxicology. The aim of this study was to evaluate the potential of PCLS as a tool in nanotoxicology studies. Silver (Ag-NPs) and zinc oxide (ZnO-NPs) nanoparticles as well as quartz particles we...

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Bibliographic Details
Main Authors: Stephanie Hirn, Nadine Haberl, Kateryna Loza, Matthias Epple, Wolfgang G. Kreyling, Barbara Rothen-Rutishauser, Markus Rehberg, Fritz Krombach
Format: Article
Language:English
Published: Beilstein-Institut 2014-12-01
Series:Beilstein Journal of Nanotechnology
Subjects:
cytokines
cytotoxicity
ex vivo
lung slices
nanoparticles
Online Access:https://doi.org/10.3762/bjnano.5.253

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