Is population screening for abdominal aortic aneurysm cost-effective?

<p>Abstract</p> <p>Background</p> <p>Ruptured abdominal aortic aneurysm (AAA) is responsible for 1–2% of all male deaths over the age of 65 years. Early detection of AAA and elective surgery can reduce the mortality risk associated with AAA. However, many patients will...

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Main Authors: Jensen Lotte, Sørensen Jan, Ehlers Lars, Bech Merete, Kjølby Mette
Format: Article
Language:English
Published: BMC 2008-11-01
Series:BMC Cardiovascular Disorders
Online Access:http://www.biomedcentral.com/1471-2261/8/32
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author Jensen Lotte
Sørensen Jan
Ehlers Lars
Bech Merete
Kjølby Mette
author_facet Jensen Lotte
Sørensen Jan
Ehlers Lars
Bech Merete
Kjølby Mette
author_sort Jensen Lotte
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Ruptured abdominal aortic aneurysm (AAA) is responsible for 1–2% of all male deaths over the age of 65 years. Early detection of AAA and elective surgery can reduce the mortality risk associated with AAA. However, many patients will not be diagnosed with AAA and have therefore an increased death risk due to the untreated AAA. It has been suggested that population screening for AAA in elderly males is effective and cost-effective. The purpose of this study was to perform a systematic review of published cost-effectiveness analyses of screening elderly men for AAA.</p> <p>Methods</p> <p>We performed a systematic search for economic evaluations in NHSEED, EconLit, Medline, Cochrane, Embase, Cinahl and two Scandinavian HTA data bases (DACEHTA and SBU). All identified studies were read in full and each study was systematically assessed according to international guidelines for critical assessment of economic evaluations in health care.</p> <p>Results</p> <p>The search identified 16 cost-effectiveness studies. Most studies considered only short term cost consequences. The studies seemed to employ a number of "optimistic" assumptions in favour of AAA screening, and included only few sensitivity analyses that assessed less optimistic assumptions.</p> <p>Conclusion</p> <p>Further analyses of cost-effectiveness of AAA screening are recommended.</p>
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spelling doaj.art-993df5489e8e4fb0b6a3929807ac37792022-12-21T23:35:11ZengBMCBMC Cardiovascular Disorders1471-22612008-11-01813210.1186/1471-2261-8-32Is population screening for abdominal aortic aneurysm cost-effective?Jensen LotteSørensen JanEhlers LarsBech MereteKjølby Mette<p>Abstract</p> <p>Background</p> <p>Ruptured abdominal aortic aneurysm (AAA) is responsible for 1–2% of all male deaths over the age of 65 years. Early detection of AAA and elective surgery can reduce the mortality risk associated with AAA. However, many patients will not be diagnosed with AAA and have therefore an increased death risk due to the untreated AAA. It has been suggested that population screening for AAA in elderly males is effective and cost-effective. The purpose of this study was to perform a systematic review of published cost-effectiveness analyses of screening elderly men for AAA.</p> <p>Methods</p> <p>We performed a systematic search for economic evaluations in NHSEED, EconLit, Medline, Cochrane, Embase, Cinahl and two Scandinavian HTA data bases (DACEHTA and SBU). All identified studies were read in full and each study was systematically assessed according to international guidelines for critical assessment of economic evaluations in health care.</p> <p>Results</p> <p>The search identified 16 cost-effectiveness studies. Most studies considered only short term cost consequences. The studies seemed to employ a number of "optimistic" assumptions in favour of AAA screening, and included only few sensitivity analyses that assessed less optimistic assumptions.</p> <p>Conclusion</p> <p>Further analyses of cost-effectiveness of AAA screening are recommended.</p>http://www.biomedcentral.com/1471-2261/8/32
spellingShingle Jensen Lotte
Sørensen Jan
Ehlers Lars
Bech Merete
Kjølby Mette
Is population screening for abdominal aortic aneurysm cost-effective?
BMC Cardiovascular Disorders
title Is population screening for abdominal aortic aneurysm cost-effective?
title_full Is population screening for abdominal aortic aneurysm cost-effective?
title_fullStr Is population screening for abdominal aortic aneurysm cost-effective?
title_full_unstemmed Is population screening for abdominal aortic aneurysm cost-effective?
title_short Is population screening for abdominal aortic aneurysm cost-effective?
title_sort is population screening for abdominal aortic aneurysm cost effective
url http://www.biomedcentral.com/1471-2261/8/32
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AT bechmerete ispopulationscreeningforabdominalaorticaneurysmcosteffective
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