Current estimates for HIV-1 production imply rapid viral clearance in lymphoid tissues.
It has recently been estimated that a single HIV-1 infected cell produces between and more than viral particles over its life span. Since body-wide estimates of the ratio of free virus to productively infected cells are smaller than and much smaller than , individual virions must be cleared rapidly....
Main Authors: | Rob J De Boer, Ruy M Ribeiro, Alan S Perelson |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-09-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2932679?pdf=render |
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