A phase I/II radiation dose escalation trial using simultaneous integrated boost technique with elective nodal irradiation and concurrent chemotherapy for unresectable esophageal Cancer

A phase I/II radiation dose escalation trial using simultaneous integrated boost technique with elective nodal irradiation and concurrent chemotherapy for unresectable esophageal Cancer

Abstract Background To investigate the safety and tolerability of simultaneous integrated boost (SIB) technique concurrent with elective nodal irradiation (ENI) and dual-drug chemotherapy for patients with unresectable esophageal cancer. Methods In phase I, the prophylactic PTV received a stable dos...

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Bibliographic Details
Main Authors: Chen Li, Wenjie Ni, Xin Wang, Zongmei Zhou, Wei Deng, Xiao Chang, Dongfu Chen, Qinfu Feng, Jun Liang, Xiaozhen Wang, Lei Deng, Wenqing Wang, Nan Bi, Tao Zhang, Zefen Xiao
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Radiation Oncology
Subjects:
Esophageal squamous cell carcinoma
Concurrent Chemoradiotherapy
Dose-escalation
Simultaneous integrated boost
Elective nodal irradiation
Online Access:http://link.springer.com/article/10.1186/s13014-019-1249-5

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