Case Series of Transcranial Direct Current Stimulation as an Augmentation Strategy for Attention Bias Modification Treatment in Adolescents with Anxiety Disorders
This article presents the results of a case series to assess the feasibility, acceptability, and clinical promise of transcranial Direct Current Stimulation (tDCS) as an augmentation strategy in clinic referred adolescents. Attention Bias Modification Treatment (ABMT) is a computer-based attention-t...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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Moscow State University of Psychology and Education
2020-10-01
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| Series: | Клиническая и специальная психология |
| Subjects: | |
| Online Access: | https://psyjournals.ru/files/116805/cpse_2020_3_Vaclavik_et_al.pdf |
| _version_ | 1818112414942494720 |
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| author | Vaclavik D. Bechor M. Foster A. Gralnik L.M. Bar-Haim Y. Pine D.S. Bikson M. Silverman W.K. Reeb-Sutherland B.C. Pettit J.W. |
| author_facet | Vaclavik D. Bechor M. Foster A. Gralnik L.M. Bar-Haim Y. Pine D.S. Bikson M. Silverman W.K. Reeb-Sutherland B.C. Pettit J.W. |
| author_sort | Vaclavik D. |
| collection | DOAJ |
| description | This article presents the results of a case series to assess the feasibility, acceptability, and clinical promise of transcranial Direct Current Stimulation (tDCS) as an augmentation strategy in clinic referred adolescents. Attention Bias Modification Treatment (ABMT) is a computer-based attention-training protocol designed to reduce rapidly deployed attention orienting to threat and thereby reduce anxiety symptom severity. Studies of ABMT reveal overall small to medium effect sizes. Advances in the neural underpinnings of attention to threat and attention-training protocols suggest the potential of tDCS of the dorsolateral prefrontal cortex (dlPFC) as a novel augmentation strategy to enhance ABMT’s efficacy (ABMT + tDCS). However, tDCS has never been tested in a sample of adolescents with anxiety disorders. Six adolescents with a primary anxiety disorder completed all four ABMT + tDCS sessions. Adverse effects were mild and transient. Adolescents and parents independently reported fair to excellent levels of satisfaction. Impairment ratings of the primary anxiety disorder significantly decreased. Further, electrophysiological data recorded via electroencephalography (EEG) suggested decreases in neural resources allocated to threat. These findings support the feasibility, acceptability, and clinical promise of tDCS as an augmentation strategy in adolescents with anxiety disorders, and provide the impetus for further investigation using randomized controlled designs in larger samples. |
| first_indexed | 2024-12-11T03:18:34Z |
| format | Article |
| id | doaj.art-9949060600a54ce0a295a99dbac04696 |
| institution | Directory Open Access Journal |
| issn | 2304-0394 |
| language | Russian |
| last_indexed | 2024-12-11T03:18:34Z |
| publishDate | 2020-10-01 |
| publisher | Moscow State University of Psychology and Education |
| record_format | Article |
| series | Клиническая и специальная психология |
| spelling | doaj.art-9949060600a54ce0a295a99dbac046962022-12-22T01:22:41ZrusMoscow State University of Psychology and EducationКлиническая и специальная психология2304-03942020-10-019310512610.17759/cpse.2020090308Case Series of Transcranial Direct Current Stimulation as an Augmentation Strategy for Attention Bias Modification Treatment in Adolescents with Anxiety DisordersVaclavik D.0https://orcid.org/0000-0002-6127-6487Bechor M.1https://orcid.org/0000-0003-1444-2670Foster A.2https://orcid.org/0000-0002-6126-4160Gralnik L.M.3https://orcid.org/0000-0002-0297-340XBar-Haim Y.4https://orcid.org/0000-0002-4630-9180Pine D.S.5https://orcid.org/0000-0002-4301-9516Bikson M.6https://orcid.org/0000-0002-0493-8333Silverman W.K.7https://orcid.org/0000-0003-4415-4098Reeb-Sutherland B.C.8https://orcid.org/0000-0001-9007-4561Pettit J.W.9https://orcid.org/0000-0003-2524-0521MS (Psychology), Doctoral Candidate, Department of Psychology, Center for Children and Families, Florida International University, USA, e-mail: dvaclavi@fiu.eduPhD, Department of Psychology, Center for Children and Families, Florida International University, e-mail: mbechor@fiu.eduMD (Psychiatry), Department of Psychiatry and Behavioral Health, Florida International University, USA, e-mail: adfoster@fiu.eduMD (Psychiatry), Department of Psychiatry and Behavioral Health, Florida International University, USA, e-mail: gralnikl@fiu.eduPhD, Adler Center for Research in Child Development and Psychopathology, Department of Psychology, Tel Aviv University, Tel Aviv, Israel, e-mail: yair1@post.tau.ac.ilMD (Psychiatry), Intramural Research Program, National Institute of Mental Health, Bethesda, USA, e-mail: pined@mail.nih.govPhD, Department of Biomedical Engineering, The City College of New York, Bethesda, USA, e-mail: bikson@ccny.cuny.eduPhD, Child Study Center, Yale University School of Medicine, Connecticut, USA, e-mail: wendy.silverman@yale.eduPhD, Department of Psychology, Center for Children and Families, Florida International University, USA, e-mail: besuther@fiu.eduPhD, Department of Psychology, Center for Children and Families, Florida International University, USA, e-mail: jpettit@fiu.eduThis article presents the results of a case series to assess the feasibility, acceptability, and clinical promise of transcranial Direct Current Stimulation (tDCS) as an augmentation strategy in clinic referred adolescents. Attention Bias Modification Treatment (ABMT) is a computer-based attention-training protocol designed to reduce rapidly deployed attention orienting to threat and thereby reduce anxiety symptom severity. Studies of ABMT reveal overall small to medium effect sizes. Advances in the neural underpinnings of attention to threat and attention-training protocols suggest the potential of tDCS of the dorsolateral prefrontal cortex (dlPFC) as a novel augmentation strategy to enhance ABMT’s efficacy (ABMT + tDCS). However, tDCS has never been tested in a sample of adolescents with anxiety disorders. Six adolescents with a primary anxiety disorder completed all four ABMT + tDCS sessions. Adverse effects were mild and transient. Adolescents and parents independently reported fair to excellent levels of satisfaction. Impairment ratings of the primary anxiety disorder significantly decreased. Further, electrophysiological data recorded via electroencephalography (EEG) suggested decreases in neural resources allocated to threat. These findings support the feasibility, acceptability, and clinical promise of tDCS as an augmentation strategy in adolescents with anxiety disorders, and provide the impetus for further investigation using randomized controlled designs in larger samples.https://psyjournals.ru/files/116805/cpse_2020_3_Vaclavik_et_al.pdfanxietyadolescentsattention bias modificationtranscranial direct current stimulationneuromodulationelectroencephalography (eeg)event related potential (erp) |
| spellingShingle | Vaclavik D. Bechor M. Foster A. Gralnik L.M. Bar-Haim Y. Pine D.S. Bikson M. Silverman W.K. Reeb-Sutherland B.C. Pettit J.W. Case Series of Transcranial Direct Current Stimulation as an Augmentation Strategy for Attention Bias Modification Treatment in Adolescents with Anxiety Disorders Клиническая и специальная психология anxiety adolescents attention bias modification transcranial direct current stimulation neuromodulation electroencephalography (eeg) event related potential (erp) |
| title | Case Series of Transcranial Direct Current Stimulation as an Augmentation Strategy for Attention Bias Modification Treatment in Adolescents with Anxiety Disorders |
| title_full | Case Series of Transcranial Direct Current Stimulation as an Augmentation Strategy for Attention Bias Modification Treatment in Adolescents with Anxiety Disorders |
| title_fullStr | Case Series of Transcranial Direct Current Stimulation as an Augmentation Strategy for Attention Bias Modification Treatment in Adolescents with Anxiety Disorders |
| title_full_unstemmed | Case Series of Transcranial Direct Current Stimulation as an Augmentation Strategy for Attention Bias Modification Treatment in Adolescents with Anxiety Disorders |
| title_short | Case Series of Transcranial Direct Current Stimulation as an Augmentation Strategy for Attention Bias Modification Treatment in Adolescents with Anxiety Disorders |
| title_sort | case series of transcranial direct current stimulation as an augmentation strategy for attention bias modification treatment in adolescents with anxiety disorders |
| topic | anxiety adolescents attention bias modification transcranial direct current stimulation neuromodulation electroencephalography (eeg) event related potential (erp) |
| url | https://psyjournals.ru/files/116805/cpse_2020_3_Vaclavik_et_al.pdf |
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