You are what you eat: food ingredients and the metabolic syndrome

When changes in the environment, specifically in energy availability or energy expenditure, occur at a greater rate than the ability of the genome or the epigenome to keep pace, the result may manifest as a metabolic disorder. The obvious solutions are, to either recreate the ancestral environment w...

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Main Author: Shireesh Apte
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council 2016-11-01
Series:Journal of Excipients and Food Chemicals
Online Access:https://jefc.scholasticahq.com/article/1109-you-are-what-you-eat-food-ingredients-and-the-metabolic-syndrome
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author Shireesh Apte
author_facet Shireesh Apte
author_sort Shireesh Apte
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description When changes in the environment, specifically in energy availability or energy expenditure, occur at a greater rate than the ability of the genome or the epigenome to keep pace, the result may manifest as a metabolic disorder. The obvious solutions are, to either recreate the ancestral environment with regard to energy consumption/expenditure and/or, to intervene epigenetically or pharmacologically, in terms of food supplementation or medicines in order to modulate and closely align the genome/epigenome to energy consumption/expenditure in the current environment. The genome and the epigenome appear to play an important role in the predisposition to, and to the development and persistence of the metabolic syndrome in recent times. The epigenomic component of this puzzle appears to be capable of significant modulation by dietary habits and food components.
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spelling doaj.art-994ae2ea8a7b4d25b036411a9c04d92c2024-03-20T18:01:34ZengInternational Pharmaceutical Excipients CouncilJournal of Excipients and Food Chemicals2150-26682016-11-0132You are what you eat: food ingredients and the metabolic syndromeShireesh ApteWhen changes in the environment, specifically in energy availability or energy expenditure, occur at a greater rate than the ability of the genome or the epigenome to keep pace, the result may manifest as a metabolic disorder. The obvious solutions are, to either recreate the ancestral environment with regard to energy consumption/expenditure and/or, to intervene epigenetically or pharmacologically, in terms of food supplementation or medicines in order to modulate and closely align the genome/epigenome to energy consumption/expenditure in the current environment. The genome and the epigenome appear to play an important role in the predisposition to, and to the development and persistence of the metabolic syndrome in recent times. The epigenomic component of this puzzle appears to be capable of significant modulation by dietary habits and food components.https://jefc.scholasticahq.com/article/1109-you-are-what-you-eat-food-ingredients-and-the-metabolic-syndrome
spellingShingle Shireesh Apte
You are what you eat: food ingredients and the metabolic syndrome
Journal of Excipients and Food Chemicals
title You are what you eat: food ingredients and the metabolic syndrome
title_full You are what you eat: food ingredients and the metabolic syndrome
title_fullStr You are what you eat: food ingredients and the metabolic syndrome
title_full_unstemmed You are what you eat: food ingredients and the metabolic syndrome
title_short You are what you eat: food ingredients and the metabolic syndrome
title_sort you are what you eat food ingredients and the metabolic syndrome
url https://jefc.scholasticahq.com/article/1109-you-are-what-you-eat-food-ingredients-and-the-metabolic-syndrome
work_keys_str_mv AT shireeshapte youarewhatyoueatfoodingredientsandthemetabolicsyndrome