New N-Alkylated Heterocyclic Compounds as Prospective NDM1 Inhibitors: Investigation of In Vitro and In Silico Properties

New N-Alkylated Heterocyclic Compounds as Prospective NDM1 Inhibitors: Investigation of In Vitro and In Silico Properties

A new family of pyrazole-based compounds (<b>1</b>–<b>15</b>) was synthesized and characterized using different physicochemical analyses, such as FTIR, UV-Visible, <sup>1</sup>H, <sup>13</sup>C NMR, and ESI/LC-MS. The compounds were evaluated for their...

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Bibliographic Details
Main Authors:	Yassine Kaddouri, Btissam Bouchal, Farid Abrigach, Mohamed El Kodadi, Mohammed Bellaoui, Ahmed Elkamhawy, Rachid Touzani, Magda H. Abdellattif
Format:	Article
Language:	English
Published:	MDPI AG 2022-06-01
Series:	Pharmaceuticals
Subjects:	synthesis pyrazole antibacterial antifungal ADME-Tox molecular docking
Online Access:	https://www.mdpi.com/1424-8247/15/7/803

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