Mucosal immunity and novel tuberculosis vaccine strategies: route of immunisation-determined T-cell homing to restricted lung mucosal compartments
Despite the use of bacille Calmette–Guérin (BCG) for almost a century, pulmonary tuberculosis (TB) continues to be a serious global health concern. Therefore, there has been a pressing need for the development of new booster vaccines to enhance existing BCG-induced immunity. Protection following muc...
Main Authors: | Rocky Lai, Sam Afkhami, Siamak Haddadi, Mangalakumari Jeyanathan, Zhou Xing |
---|---|
Format: | Article |
Language: | English |
Published: |
European Respiratory Society
2015-06-01
|
Series: | European Respiratory Review |
Online Access: | http://err.ersjournals.com/content/24/136/356.full |
Similar Items
-
Age at Mycobacterium bovis BCG Priming Has Limited Impact on Anti-Tuberculosis Immunity Boosted by Respiratory Mucosal AdHu5Ag85A Immunization in a Murine Model.
by: Daniela Damjanovic, et al.
Published: (2015-01-01) -
Mucosal-Pull Induction of Lung-Resident Memory CD8 T Cells in Parenteral TB Vaccine-Primed Hosts Requires Cognate Antigens and CD4 T Cells
by: Siamak Haddadi, et al.
Published: (2019-09-01) -
Advancing Immunotherapeutic Vaccine Strategies Against Pulmonary Tuberculosis
by: Sam Afkhami, et al.
Published: (2020-09-01) -
Respiratory immunisation and mucosal immunity against influenza
by: Martini, V
Published: (2022) -
Aerosol delivery, but not intramuscular injection, of adenovirus-vectored tuberculosis vaccine induces respiratory-mucosal immunity in humans
by: Mangalakumari Jeyanathan, et al.
Published: (2022-02-01)