A highly efficient transcriptome-based biosynthesis of non-ethanol chemicals in Crabtree negative Saccharomyces cerevisiae

A highly efficient transcriptome-based biosynthesis of non-ethanol chemicals in Crabtree negative Saccharomyces cerevisiae

Abstract Background Owing to the Crabtree effect, Saccharomyces cerevisiae produces a large amount of ethanol in the presence of oxygen and excess glucose, leading to a loss of carbon for the biosynthesis of non-ethanol chemicals. In the present study, the potential of a newly constructed Crabtree n...

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Bibliographic Details
Main Authors: Zhen Yao, Yufeng Guo, Huan Wang, Yun Chen, Qinhong Wang, Jens Nielsen, Zongjie Dai
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
Microbial production
Crabtree negative
Chassis strain
Saccharomyces cerevisiae
Crabtree effect
Fatty acids
Online Access:https://doi.org/10.1186/s13068-023-02276-5

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