Impact of obesity on outcomes of extracorporeal membrane oxygenation support: a systematic review and meta-analysis
Abstract Background Extracorporeal membrane oxygenation (ECMO) is used when standard methods of standard treatment methods are not successful. Obese patients present unique challenges during ECMO due to large body size hindering sufficient flows, difficulties with patient positioning and anatomical...
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | BMC Pulmonary Medicine |
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| Online Access: | https://doi.org/10.1186/s12890-024-02971-5 |
| _version_ | 1797233840817700864 |
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| author | Xinhua Huang Xiaoqing Lin |
| author_facet | Xinhua Huang Xiaoqing Lin |
| author_sort | Xinhua Huang |
| collection | DOAJ |
| description | Abstract Background Extracorporeal membrane oxygenation (ECMO) is used when standard methods of standard treatment methods are not successful. Obese patients present unique challenges during ECMO due to large body size hindering sufficient flows, difficulties with patient positioning and anatomical landmark identification, and restricted radiology scans. This meta-analysis aims to investigate the impact of obesity on the outcomes of patients undergoing ECMO. Methods Databases (PubMed, Embase, and Scopus databases) were searched to identify relevant studies published until July 2023. Data were reported as odds ratios (OR) with 95% confidence interval (CI), and the descriptive data were reported as standard difference of means (SDM) by a random effects model. Results A literature search identified 345 studies. Of them, 18 studies met the inclusion criteria. The findings from the meta-analysis revealed no significant association between obesity and survival outcomes after ECMO (odds ratio (OR): 0.91, 95% confidence interval (CI): 0.70–1.17, p: 0.46). Moreover, no comparative significant differences were found between obese and non-obese individuals on the duration of ECMO procedure (standardized mean difference (SMD): 0.07, -0.03–0.17), length of hospital stay (-0.03, -0.19 to 0.12), and duration of ventilation support (-0.10, -0.44 to 0.24). Conclusion The meta-analysis findings suggest no significant impact of obesity on the survival outcomes after the ECMO procedure. There was no significant impact of obesity on the duration of ECMO procedures, length of hospital stay, and duration of ventilation support. |
| first_indexed | 2024-04-24T16:22:34Z |
| format | Article |
| id | doaj.art-995d560b996f450f9eda469202c0e68e |
| institution | Directory Open Access Journal |
| issn | 1471-2466 |
| language | English |
| last_indexed | 2024-04-24T16:22:34Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pulmonary Medicine |
| spelling | doaj.art-995d560b996f450f9eda469202c0e68e2024-03-31T11:09:41ZengBMCBMC Pulmonary Medicine1471-24662024-03-0124111110.1186/s12890-024-02971-5Impact of obesity on outcomes of extracorporeal membrane oxygenation support: a systematic review and meta-analysisXinhua Huang0Xiaoqing Lin1Department of Geriatric, HuZhou Third Municipal Hospital, the Affiliated Hospital of Huzhou UniversityDepartment of Geriatric, HuZhou Third Municipal Hospital, the Affiliated Hospital of Huzhou UniversityAbstract Background Extracorporeal membrane oxygenation (ECMO) is used when standard methods of standard treatment methods are not successful. Obese patients present unique challenges during ECMO due to large body size hindering sufficient flows, difficulties with patient positioning and anatomical landmark identification, and restricted radiology scans. This meta-analysis aims to investigate the impact of obesity on the outcomes of patients undergoing ECMO. Methods Databases (PubMed, Embase, and Scopus databases) were searched to identify relevant studies published until July 2023. Data were reported as odds ratios (OR) with 95% confidence interval (CI), and the descriptive data were reported as standard difference of means (SDM) by a random effects model. Results A literature search identified 345 studies. Of them, 18 studies met the inclusion criteria. The findings from the meta-analysis revealed no significant association between obesity and survival outcomes after ECMO (odds ratio (OR): 0.91, 95% confidence interval (CI): 0.70–1.17, p: 0.46). Moreover, no comparative significant differences were found between obese and non-obese individuals on the duration of ECMO procedure (standardized mean difference (SMD): 0.07, -0.03–0.17), length of hospital stay (-0.03, -0.19 to 0.12), and duration of ventilation support (-0.10, -0.44 to 0.24). Conclusion The meta-analysis findings suggest no significant impact of obesity on the survival outcomes after the ECMO procedure. There was no significant impact of obesity on the duration of ECMO procedures, length of hospital stay, and duration of ventilation support.https://doi.org/10.1186/s12890-024-02971-5ObesityMortalityExtracorporeal membrane oxygenationMorbidity |
| spellingShingle | Xinhua Huang Xiaoqing Lin Impact of obesity on outcomes of extracorporeal membrane oxygenation support: a systematic review and meta-analysis BMC Pulmonary Medicine Obesity Mortality Extracorporeal membrane oxygenation Morbidity |
| title | Impact of obesity on outcomes of extracorporeal membrane oxygenation support: a systematic review and meta-analysis |
| title_full | Impact of obesity on outcomes of extracorporeal membrane oxygenation support: a systematic review and meta-analysis |
| title_fullStr | Impact of obesity on outcomes of extracorporeal membrane oxygenation support: a systematic review and meta-analysis |
| title_full_unstemmed | Impact of obesity on outcomes of extracorporeal membrane oxygenation support: a systematic review and meta-analysis |
| title_short | Impact of obesity on outcomes of extracorporeal membrane oxygenation support: a systematic review and meta-analysis |
| title_sort | impact of obesity on outcomes of extracorporeal membrane oxygenation support a systematic review and meta analysis |
| topic | Obesity Mortality Extracorporeal membrane oxygenation Morbidity |
| url | https://doi.org/10.1186/s12890-024-02971-5 |
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