Eficácia anti-helmíntica comparativa da associação albendazole, levamisole e ivermectina à moxidectina em ovinos Comparative anthelmintic efficacy of the association albendazol, levamisol and ivermectin to moxidectin in sheep
Avaliou-se a eficácia anti-helmíntica da associação de albendazole 2,0%, cloridrato de levamisole 2,55% e ivermectina 0,08% comparativamente à moxidectina 1% em ovinos naturalmente infectados. Foram selecionados 24 ovinos para a composição de três grupos experimentais com oito animais cada: T1, ovin...
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| Format: | Article |
| Language: | English |
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Embrapa Informação Tecnológica
2007-06-01
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| Series: | Pesquisa Agropecuária Brasileira |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2007000600017 |
| _version_ | 1828805355790925824 |
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| author | Carolina Buzzulini Américo Garcia da Silva Sobrinho Alvimar José da Costa Thaís Rabelo dos Santos Fernando de Almeida Borges Vando Edésio Soares |
| author_facet | Carolina Buzzulini Américo Garcia da Silva Sobrinho Alvimar José da Costa Thaís Rabelo dos Santos Fernando de Almeida Borges Vando Edésio Soares |
| author_sort | Carolina Buzzulini |
| collection | DOAJ |
| description | Avaliou-se a eficácia anti-helmíntica da associação de albendazole 2,0%, cloridrato de levamisole 2,55% e ivermectina 0,08% comparativamente à moxidectina 1% em ovinos naturalmente infectados. Foram selecionados 24 ovinos para a composição de três grupos experimentais com oito animais cada: T1, ovinos tratados com a associação albendazole, levamisole e ivermectina, na dosagem de 1 mL 4 kg-1 de peso corporal; T2, ovinos tratados com moxidectina, na dosagem de 1 mL 50 kg-1 de peso corporal e T3, ovinos sem tratamento anti-helmíntico. Foram realizadas contagens de ovos por grama de fezes (OPG) no primeiro, terceiro, quinto e sétimo dia após os tratamentos. No sétimo dia todos os ovinos foram necropsiados e todos os helmintos encontrados no trato gastrintestinal foram quantificados e identificados quanto ao gênero e à espécie. A associação dos diferentes princípios ativos foi 100% eficaz no combate às espécies Cooperia punctata, C. pectinata, C. spatulata, Trichostrongylus axei, Oesophagostomum columbianum, Trichuris ovis, C. curticei e Strongyloides papillosus e, a moxidectina eliminou as seis primeiras espécies citadas. Contra Haemonchus contortus a associação apresentou eficácia superior (93%) à moxidectina (51,4%). Ambas formulações foram eficazes contra Trichostrongylus colubriformis. A associação medicamentosa utilizada constitui alternativa no controle das nematodioses ovinas.<br>The anthelmintic efficacy of 2.0% albendazol, 2.55% levamisol chloridrate and 0.08% ivermectin formulation to 1% moxidectin in sheep naturally infected with gastrointestinal nematodes was compared. Twenty-four animals were selected by faecal egg counts (FEC) means, composing three experimental groups with eight sheep each: T1, sheep treated with albendazol, levamisol and ivermectin association; T2, sheep treated with 1% moxidectin and T3, untreated group. FEC was estimated at 1st, 3rd, 5th and 7th day post-treatment. All animals were slaughtered at 7th day post-treatment to quantify and identify the nematode burden. The association was 100% effective against eight of ten helminth species (Cooperia punctata, C. pectinata, C. curticei, C. spatulata, Strongyloides papillosus, Trichostrongylus axei, Oesophagostomum columbianum and Trichuris ovis), while the moxidectin removed only six of these species. It also had superior efficacy against Haemonchus contortus (93%) when compared to the 1% moxidectin (51.4%). Both formulations showed similar efficacy against Trichostrongylus colubriformis. Therefore, the anthelmintic association can be an alternative on sheep nematodiosis control. |
| first_indexed | 2024-12-12T07:54:28Z |
| format | Article |
| id | doaj.art-99617b7e2896414084fd6d86aec4d47f |
| institution | Directory Open Access Journal |
| issn | 0100-204X 1678-3921 |
| language | English |
| last_indexed | 2024-12-12T07:54:28Z |
| publishDate | 2007-06-01 |
| publisher | Embrapa Informação Tecnológica |
| record_format | Article |
| series | Pesquisa Agropecuária Brasileira |
| spelling | doaj.art-99617b7e2896414084fd6d86aec4d47f2022-12-22T00:32:22ZengEmbrapa Informação TecnológicaPesquisa Agropecuária Brasileira0100-204X1678-39212007-06-0142689189510.1590/S0100-204X2007000600017Eficácia anti-helmíntica comparativa da associação albendazole, levamisole e ivermectina à moxidectina em ovinos Comparative anthelmintic efficacy of the association albendazol, levamisol and ivermectin to moxidectin in sheepCarolina BuzzuliniAmérico Garcia da Silva SobrinhoAlvimar José da CostaThaís Rabelo dos SantosFernando de Almeida BorgesVando Edésio SoaresAvaliou-se a eficácia anti-helmíntica da associação de albendazole 2,0%, cloridrato de levamisole 2,55% e ivermectina 0,08% comparativamente à moxidectina 1% em ovinos naturalmente infectados. Foram selecionados 24 ovinos para a composição de três grupos experimentais com oito animais cada: T1, ovinos tratados com a associação albendazole, levamisole e ivermectina, na dosagem de 1 mL 4 kg-1 de peso corporal; T2, ovinos tratados com moxidectina, na dosagem de 1 mL 50 kg-1 de peso corporal e T3, ovinos sem tratamento anti-helmíntico. Foram realizadas contagens de ovos por grama de fezes (OPG) no primeiro, terceiro, quinto e sétimo dia após os tratamentos. No sétimo dia todos os ovinos foram necropsiados e todos os helmintos encontrados no trato gastrintestinal foram quantificados e identificados quanto ao gênero e à espécie. A associação dos diferentes princípios ativos foi 100% eficaz no combate às espécies Cooperia punctata, C. pectinata, C. spatulata, Trichostrongylus axei, Oesophagostomum columbianum, Trichuris ovis, C. curticei e Strongyloides papillosus e, a moxidectina eliminou as seis primeiras espécies citadas. Contra Haemonchus contortus a associação apresentou eficácia superior (93%) à moxidectina (51,4%). Ambas formulações foram eficazes contra Trichostrongylus colubriformis. A associação medicamentosa utilizada constitui alternativa no controle das nematodioses ovinas.<br>The anthelmintic efficacy of 2.0% albendazol, 2.55% levamisol chloridrate and 0.08% ivermectin formulation to 1% moxidectin in sheep naturally infected with gastrointestinal nematodes was compared. Twenty-four animals were selected by faecal egg counts (FEC) means, composing three experimental groups with eight sheep each: T1, sheep treated with albendazol, levamisol and ivermectin association; T2, sheep treated with 1% moxidectin and T3, untreated group. FEC was estimated at 1st, 3rd, 5th and 7th day post-treatment. All animals were slaughtered at 7th day post-treatment to quantify and identify the nematode burden. The association was 100% effective against eight of ten helminth species (Cooperia punctata, C. pectinata, C. curticei, C. spatulata, Strongyloides papillosus, Trichostrongylus axei, Oesophagostomum columbianum and Trichuris ovis), while the moxidectin removed only six of these species. It also had superior efficacy against Haemonchus contortus (93%) when compared to the 1% moxidectin (51.4%). Both formulations showed similar efficacy against Trichostrongylus colubriformis. Therefore, the anthelmintic association can be an alternative on sheep nematodiosis control.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2007000600017anti-helmínticoscontrolenematodiose ovinaanthelminthicscontrolsheep nematodiosis |
| spellingShingle | Carolina Buzzulini Américo Garcia da Silva Sobrinho Alvimar José da Costa Thaís Rabelo dos Santos Fernando de Almeida Borges Vando Edésio Soares Eficácia anti-helmíntica comparativa da associação albendazole, levamisole e ivermectina à moxidectina em ovinos Comparative anthelmintic efficacy of the association albendazol, levamisol and ivermectin to moxidectin in sheep Pesquisa Agropecuária Brasileira anti-helmínticos controle nematodiose ovina anthelminthics control sheep nematodiosis |
| title | Eficácia anti-helmíntica comparativa da associação albendazole, levamisole e ivermectina à moxidectina em ovinos Comparative anthelmintic efficacy of the association albendazol, levamisol and ivermectin to moxidectin in sheep |
| title_full | Eficácia anti-helmíntica comparativa da associação albendazole, levamisole e ivermectina à moxidectina em ovinos Comparative anthelmintic efficacy of the association albendazol, levamisol and ivermectin to moxidectin in sheep |
| title_fullStr | Eficácia anti-helmíntica comparativa da associação albendazole, levamisole e ivermectina à moxidectina em ovinos Comparative anthelmintic efficacy of the association albendazol, levamisol and ivermectin to moxidectin in sheep |
| title_full_unstemmed | Eficácia anti-helmíntica comparativa da associação albendazole, levamisole e ivermectina à moxidectina em ovinos Comparative anthelmintic efficacy of the association albendazol, levamisol and ivermectin to moxidectin in sheep |
| title_short | Eficácia anti-helmíntica comparativa da associação albendazole, levamisole e ivermectina à moxidectina em ovinos Comparative anthelmintic efficacy of the association albendazol, levamisol and ivermectin to moxidectin in sheep |
| title_sort | eficacia anti helmintica comparativa da associacao albendazole levamisole e ivermectina a moxidectina em ovinos comparative anthelmintic efficacy of the association albendazol levamisol and ivermectin to moxidectin in sheep |
| topic | anti-helmínticos controle nematodiose ovina anthelminthics control sheep nematodiosis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2007000600017 |
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