Development and validation of MRI-based model for the preoperative prediction of macrotrabecular hepatocellular carcinoma subtype

Key points Clinicoradiologic model has a good performance in diagnosing MTHCC. In validation set, models 2 and 3 did not significantly improve predictive performance compared to clinicoradiologic model. Clinicoradiologic model yielded higher clinical benefit at MTHCC threshold probability of 10%. Cl...

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Main Authors: Ismail Bilal Masokano, Yigang Pei, Juan Chen, Wenguang Liu, Simin Xie, Huaping Liu, Deyun Feng, Qiongqiong He, Wenzheng Li
Format: Article
Language:English
Published: SpringerOpen 2022-12-01
Series:Insights into Imaging
Subjects:
Online Access:https://doi.org/10.1186/s13244-022-01333-1
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author Ismail Bilal Masokano
Yigang Pei
Juan Chen
Wenguang Liu
Simin Xie
Huaping Liu
Deyun Feng
Qiongqiong He
Wenzheng Li
author_facet Ismail Bilal Masokano
Yigang Pei
Juan Chen
Wenguang Liu
Simin Xie
Huaping Liu
Deyun Feng
Qiongqiong He
Wenzheng Li
author_sort Ismail Bilal Masokano
collection DOAJ
description Key points Clinicoradiologic model has a good performance in diagnosing MTHCC. In validation set, models 2 and 3 did not significantly improve predictive performance compared to clinicoradiologic model. Clinicoradiologic model yielded higher clinical benefit at MTHCC threshold probability of 10%. Clinicoradiologic model is as beneficial as model 3, yet simpler and easier.
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spelling doaj.art-9962805fcd9644c2b4502fd529f0a0392022-12-25T12:18:49ZengSpringerOpenInsights into Imaging1869-41012022-12-0113111510.1186/s13244-022-01333-1Development and validation of MRI-based model for the preoperative prediction of macrotrabecular hepatocellular carcinoma subtypeIsmail Bilal Masokano0Yigang Pei1Juan Chen2Wenguang Liu3Simin Xie4Huaping Liu5Deyun Feng6Qiongqiong He7Wenzheng Li8Department of Radiology, Xiangya Hospital, Central South UniversityDepartment of Radiology, Xiangya Hospital, Central South UniversityDepartment of Radiology, Xiangya Hospital, Central South UniversityDepartment of Radiology, Xiangya Hospital, Central South UniversityDepartment of Radiology, Xiangya Hospital, Central South UniversityDepartment of Radiology, The Third Xiangya Hospital, Central South UniversityDepartment of Pathology, Xiangya Hospital, Central South UniversityDepartment of Pathology, Xiangya Hospital, Central South UniversityDepartment of Radiology, Xiangya Hospital, Central South UniversityKey points Clinicoradiologic model has a good performance in diagnosing MTHCC. In validation set, models 2 and 3 did not significantly improve predictive performance compared to clinicoradiologic model. Clinicoradiologic model yielded higher clinical benefit at MTHCC threshold probability of 10%. Clinicoradiologic model is as beneficial as model 3, yet simpler and easier.https://doi.org/10.1186/s13244-022-01333-1Macrotrabecular hepatocellular carcinomaMagnetic resonance imagingNomogramsDecision-making
spellingShingle Ismail Bilal Masokano
Yigang Pei
Juan Chen
Wenguang Liu
Simin Xie
Huaping Liu
Deyun Feng
Qiongqiong He
Wenzheng Li
Development and validation of MRI-based model for the preoperative prediction of macrotrabecular hepatocellular carcinoma subtype
Insights into Imaging
Macrotrabecular hepatocellular carcinoma
Magnetic resonance imaging
Nomograms
Decision-making
title Development and validation of MRI-based model for the preoperative prediction of macrotrabecular hepatocellular carcinoma subtype
title_full Development and validation of MRI-based model for the preoperative prediction of macrotrabecular hepatocellular carcinoma subtype
title_fullStr Development and validation of MRI-based model for the preoperative prediction of macrotrabecular hepatocellular carcinoma subtype
title_full_unstemmed Development and validation of MRI-based model for the preoperative prediction of macrotrabecular hepatocellular carcinoma subtype
title_short Development and validation of MRI-based model for the preoperative prediction of macrotrabecular hepatocellular carcinoma subtype
title_sort development and validation of mri based model for the preoperative prediction of macrotrabecular hepatocellular carcinoma subtype
topic Macrotrabecular hepatocellular carcinoma
Magnetic resonance imaging
Nomograms
Decision-making
url https://doi.org/10.1186/s13244-022-01333-1
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