P113 DIURNAL RHYTHM OF CENTRAL BLOOD PRESSURE DURING TWENTY-FOUR-HOUR AMBULATORY MONITORING

It’s known that ABPM is better in diagnosing hypertension than office-based measurements. Growing evidence supports that cBP is stronger predictor of cardiovascular risk than brachial BP. Dipping status of subjects can be assessed based on night-to-day BP ratio derived from ABPM. However, there is n...

Full description

Bibliographic Details
Main Author: Bela Benczur
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125930125/view
_version_ 1811337021048750080
author Bela Benczur
author_facet Bela Benczur
author_sort Bela Benczur
collection DOAJ
description It’s known that ABPM is better in diagnosing hypertension than office-based measurements. Growing evidence supports that cBP is stronger predictor of cardiovascular risk than brachial BP. Dipping status of subjects can be assessed based on night-to-day BP ratio derived from ABPM. However, there is no data regarding diurnal rhythm of central hemodynamics. Arteriograph 24 is suitable for 24-hour monitoring of both central and brachial BP. The aim of our study was to compare the 24-hour pattern of peripherial and central BP in same patients. Patients and methods: 24-hour aortic BP-monitoring was performed with Arteriograph 24 in 46 subjects (30 male, 16 female). Measurements were carried out with Arteriograph 24 – a combination of a “single” Arteriograph and an ABPM. Mean age of patients were 55.36 years. Their dipper status was assessed according to the ESH-guidelines and the circadian variation of central hemodynamics was determined as the difference of peripherial and central BP during day and night. Results: Only 7 of 46 subjects were non-dipper according to their brachial BP. All of them had elevated central BP at night. In contrast we observed elevated AIx and higher cBP during nighttime in further 30 cases who had dipping of nighttime brachial BP. Conclusions: cBP have diurnal rhythm but the circadian variation of cBP is not necessarily parallel with the corresponding peripherial values. Theoretically elevated peripherial vascular resistance during night helps to maintain the appropriate cBP to provide the cerebral, coronary and renal perfusion. If this observation is confirmed by further large-scale trials the clinical implications of dipping status could be reconsidered.
first_indexed 2024-04-13T17:47:59Z
format Article
id doaj.art-996365f9ef464ca8a6621a50aa734e55
institution Directory Open Access Journal
issn 1876-4401
language English
last_indexed 2024-04-13T17:47:59Z
publishDate 2018-12-01
publisher BMC
record_format Article
series Artery Research
spelling doaj.art-996365f9ef464ca8a6621a50aa734e552022-12-22T02:36:50ZengBMCArtery Research1876-44012018-12-012410.1016/j.artres.2018.10.166P113 DIURNAL RHYTHM OF CENTRAL BLOOD PRESSURE DURING TWENTY-FOUR-HOUR AMBULATORY MONITORINGBela BenczurIt’s known that ABPM is better in diagnosing hypertension than office-based measurements. Growing evidence supports that cBP is stronger predictor of cardiovascular risk than brachial BP. Dipping status of subjects can be assessed based on night-to-day BP ratio derived from ABPM. However, there is no data regarding diurnal rhythm of central hemodynamics. Arteriograph 24 is suitable for 24-hour monitoring of both central and brachial BP. The aim of our study was to compare the 24-hour pattern of peripherial and central BP in same patients. Patients and methods: 24-hour aortic BP-monitoring was performed with Arteriograph 24 in 46 subjects (30 male, 16 female). Measurements were carried out with Arteriograph 24 – a combination of a “single” Arteriograph and an ABPM. Mean age of patients were 55.36 years. Their dipper status was assessed according to the ESH-guidelines and the circadian variation of central hemodynamics was determined as the difference of peripherial and central BP during day and night. Results: Only 7 of 46 subjects were non-dipper according to their brachial BP. All of them had elevated central BP at night. In contrast we observed elevated AIx and higher cBP during nighttime in further 30 cases who had dipping of nighttime brachial BP. Conclusions: cBP have diurnal rhythm but the circadian variation of cBP is not necessarily parallel with the corresponding peripherial values. Theoretically elevated peripherial vascular resistance during night helps to maintain the appropriate cBP to provide the cerebral, coronary and renal perfusion. If this observation is confirmed by further large-scale trials the clinical implications of dipping status could be reconsidered.https://www.atlantis-press.com/article/125930125/view
spellingShingle Bela Benczur
P113 DIURNAL RHYTHM OF CENTRAL BLOOD PRESSURE DURING TWENTY-FOUR-HOUR AMBULATORY MONITORING
Artery Research
title P113 DIURNAL RHYTHM OF CENTRAL BLOOD PRESSURE DURING TWENTY-FOUR-HOUR AMBULATORY MONITORING
title_full P113 DIURNAL RHYTHM OF CENTRAL BLOOD PRESSURE DURING TWENTY-FOUR-HOUR AMBULATORY MONITORING
title_fullStr P113 DIURNAL RHYTHM OF CENTRAL BLOOD PRESSURE DURING TWENTY-FOUR-HOUR AMBULATORY MONITORING
title_full_unstemmed P113 DIURNAL RHYTHM OF CENTRAL BLOOD PRESSURE DURING TWENTY-FOUR-HOUR AMBULATORY MONITORING
title_short P113 DIURNAL RHYTHM OF CENTRAL BLOOD PRESSURE DURING TWENTY-FOUR-HOUR AMBULATORY MONITORING
title_sort p113 diurnal rhythm of central blood pressure during twenty four hour ambulatory monitoring
url https://www.atlantis-press.com/article/125930125/view
work_keys_str_mv AT belabenczur p113diurnalrhythmofcentralbloodpressureduringtwentyfourhourambulatorymonitoring