Elevated pulse pressure and its associations with demographic and clinical parameters in a clinically representative sample of outpatients with psychotic disorders
Elevated pulse pressure is associated with metabolic and neurocognitive diseases. Preliminary small-scale studies among patients with psychotic disorders have indicated that these patients had an increased pulse pressure compared with controls. However, it is unclear whether and how these associatio...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2022-05-01
|
| Series: | BJPsych Open |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2056472422000527/type/journal_article |
| _version_ | 1811156928901939200 |
|---|---|
| author | Christopher Holmberg Jarl Torgerson Andreas Gremyr |
| author_facet | Christopher Holmberg Jarl Torgerson Andreas Gremyr |
| author_sort | Christopher Holmberg |
| collection | DOAJ |
| description | Elevated pulse pressure is associated with metabolic and neurocognitive diseases. Preliminary small-scale studies among patients with psychotic disorders have indicated that these patients had an increased pulse pressure compared with controls. However, it is unclear whether and how these associations are manifested among larger heterogenous samples of patients with psychotic disorders. We examined elevated pulse pressure and its associations with demographic and clinical characteristics in a clinically representative sample of outpatients with psychotic disorders (n = 1289). In a subsample (n = 343), we also examined associations with six domains of functioning. Controlling for age and cardiovascular disease, body mass index (BMI) and employment status independently predicted the odds ratio of having elevated pulse pressure. Elevated pulse pressure was also primarily associated with the physical domains of functioning. Outpatients with psychotic disorders that have high BMI and are unemployed thus seem to be at increased risk for elevated pulse pressure and should therefore be particularly considered for blood pressure screenings. |
| first_indexed | 2024-04-10T04:58:14Z |
| format | Article |
| id | doaj.art-996d99a3d41c452d9819bb8b63679e9f |
| institution | Directory Open Access Journal |
| issn | 2056-4724 |
| language | English |
| last_indexed | 2024-04-10T04:58:14Z |
| publishDate | 2022-05-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | BJPsych Open |
| spelling | doaj.art-996d99a3d41c452d9819bb8b63679e9f2023-03-09T12:29:19ZengCambridge University PressBJPsych Open2056-47242022-05-01810.1192/bjo.2022.52Elevated pulse pressure and its associations with demographic and clinical parameters in a clinically representative sample of outpatients with psychotic disordersChristopher Holmberg0https://orcid.org/0000-0002-6493-3817Jarl Torgerson1Andreas Gremyr2Department of Psychotic Disorders, Sahlgrenska University Hospital, and Department of Health and Care Sciences, University of Gothenburg, Gothenburg, SwedenDepartment of Psychotic Disorders, Sahlgrenska University Hospital, Gothenburg, SwedenDepartment of Psychotic Disorders, Sahlgrenska University Hospital, Gothenburg, and Jönköping Academy for Improvement of Health and Welfare, Jönköping University, Jönköping, SwedenElevated pulse pressure is associated with metabolic and neurocognitive diseases. Preliminary small-scale studies among patients with psychotic disorders have indicated that these patients had an increased pulse pressure compared with controls. However, it is unclear whether and how these associations are manifested among larger heterogenous samples of patients with psychotic disorders. We examined elevated pulse pressure and its associations with demographic and clinical characteristics in a clinically representative sample of outpatients with psychotic disorders (n = 1289). In a subsample (n = 343), we also examined associations with six domains of functioning. Controlling for age and cardiovascular disease, body mass index (BMI) and employment status independently predicted the odds ratio of having elevated pulse pressure. Elevated pulse pressure was also primarily associated with the physical domains of functioning. Outpatients with psychotic disorders that have high BMI and are unemployed thus seem to be at increased risk for elevated pulse pressure and should therefore be particularly considered for blood pressure screenings.https://www.cambridge.org/core/product/identifier/S2056472422000527/type/journal_articlePsychotic disordersschizophreniaoutpatient treatmentcomorbidityprimary care |
| spellingShingle | Christopher Holmberg Jarl Torgerson Andreas Gremyr Elevated pulse pressure and its associations with demographic and clinical parameters in a clinically representative sample of outpatients with psychotic disorders BJPsych Open Psychotic disorders schizophrenia outpatient treatment comorbidity primary care |
| title | Elevated pulse pressure and its associations with demographic and clinical parameters in a clinically representative sample of outpatients with psychotic disorders |
| title_full | Elevated pulse pressure and its associations with demographic and clinical parameters in a clinically representative sample of outpatients with psychotic disorders |
| title_fullStr | Elevated pulse pressure and its associations with demographic and clinical parameters in a clinically representative sample of outpatients with psychotic disorders |
| title_full_unstemmed | Elevated pulse pressure and its associations with demographic and clinical parameters in a clinically representative sample of outpatients with psychotic disorders |
| title_short | Elevated pulse pressure and its associations with demographic and clinical parameters in a clinically representative sample of outpatients with psychotic disorders |
| title_sort | elevated pulse pressure and its associations with demographic and clinical parameters in a clinically representative sample of outpatients with psychotic disorders |
| topic | Psychotic disorders schizophrenia outpatient treatment comorbidity primary care |
| url | https://www.cambridge.org/core/product/identifier/S2056472422000527/type/journal_article |
| work_keys_str_mv | AT christopherholmberg elevatedpulsepressureanditsassociationswithdemographicandclinicalparametersinaclinicallyrepresentativesampleofoutpatientswithpsychoticdisorders AT jarltorgerson elevatedpulsepressureanditsassociationswithdemographicandclinicalparametersinaclinicallyrepresentativesampleofoutpatientswithpsychoticdisorders AT andreasgremyr elevatedpulsepressureanditsassociationswithdemographicandclinicalparametersinaclinicallyrepresentativesampleofoutpatientswithpsychoticdisorders |