Sirtuins 1 and 2 in the Acute Period After Photothrombotic Stroke: Expression, Localization and Involvement in Apoptosis

Sirtuins 1 and 2 in the Acute Period After Photothrombotic Stroke: Expression, Localization and Involvement in Apoptosis

Sirtuins (SIRTs) are NAD+- dependent histone deacetylases. They are involved in a variety of biological pathways and are thought to be a promising target for treating several human disorders. Although evidence is piling up to support the neuroprotective role of SIRTs in ischemic stroke, the role of...

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Bibliographic Details
Main Authors: Moez Eid, Valentina Dzreyan, Svetlana Demyanenko
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Physiology
Subjects:
histone deacetylases
sirtuins
photothrombotic stroke
penumbra
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.782684/full

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