Bivariate One Strain Many Compounds Designs Expand the Secondary Metabolite Production Space in <i>Corallococcus coralloides</i>

Bivariate One Strain Many Compounds Designs Expand the Secondary Metabolite Production Space in <i>Corallococcus coralloides</i>

The scarcely investigated myxobacterium <i>Corallococcus coralloides</i> holds a large genome containing many uncharacterized biosynthetic gene clusters (BGCs) that potentially encode the synthesis of entirely new natural products. Despite its promising genomic potential, suitable cultiv...

Full description

Bibliographic Details
Main Authors:	Anton Lindig, Jenny Schwarz, Georg Hubmann, Katrin Rosenthal, Stephan Lütz
Format:	Article
Language:	English
Published:	MDPI AG 2023-10-01
Series:	Microorganisms
Subjects:	myxobacteria secondary metabolites multifactorial OSMAC screening method
Online Access:	https://www.mdpi.com/2076-2607/11/10/2592

Similar Items

Triaging of Culture Conditions for Enhanced Secondary Metabolite Diversity from Different Bacteria
by: Jenny Schwarz, et al.
Published: (2021-01-01)

<i>Corallococcus soli</i> sp. Nov., a Soil Myxobacterium Isolated from Subtropical Climate, Chalus County, Iran, and Its Potential to Produce Secondary Metabolites
by: Zahra Khosravi Babadi, et al.
Published: (2022-06-01)

Secretory CAZymes profile and GH19 enzymes analysis of Corallococcus silvisoli c25j21
by: Xiaoli Zhou, et al.
Published: (2024-02-01)

Genome Sequencing and Pan-Genome Analysis of 23 Corallococcus spp. Strains Reveal Unexpected Diversity, With Particular Plasticity of Predatory Gene Sets
by: Paul G. Livingstone, et al.
Published: (2018-12-01)

Cryptic Secondary Metabolites from the Sponge-Associated Fungus <i>Aspergillus ochraceus</i>
by: Marian Frank, et al.
Published: (2019-02-01)

In silico characterization of a novel putative aerotaxis chemosensory system in the myxobacterium, Corallococcus coralloides
by: Gaurav Sharma, et al.
Published: (2018-10-01)

Isolation and Characterization of Two New Metabolites from the Sponge-Derived Fungus <i>Aspergillus</i> sp. LS34 by OSMAC Approach
by: Wei Li, et al.
Published: (2019-05-01)

Coralmycin Derivatives with Potent Anti-Gram Negative Activity Produced by the Myxobacteria <i>Corallococcus coralloides</i> M23
by: Bo-Min Kim, et al.
Published: (2019-04-01)

DETECTION OF ANTIMICROBIAL COMPOUNDS FROM THERMOPHILIC ACTINOMYCETES USING ONE STRAIN MANY COMPOUNDS (OSMAC) APPROACH
by: Endah Wati Zahroh, et al.
Published: (2022-08-01)

Exploration of Diverse Secondary Metabolites From Streptomyces sp. YINM00001, Using Genome Mining and One Strain Many Compounds Approach
by: Tao Liu, et al.
Published: (2022-02-01)

A systems approach using OSMAC, Log P and NMR fingerprinting: An approach to novelty
by: Miaomiao Liu, et al.
Published: (2017-12-01)

OSMAC-Based Discovery and Biosynthetic Gene Clusters Analysis of Secondary Metabolites from Marine-Derived <i>Streptomyces globisporus</i> SCSIO LCY30
by: Yanqing Li, et al.
Published: (2023-12-01)

Metabolomic Strategies to Improve Chemical Information from OSMAC Studies of Endophytic Fungi
by: Fernanda Motta Ribeiro da Silva, et al.
Published: (2023-02-01)

Marine-derived myxobacteria of the suborder Nannocystineae: An underexplored source of structurally intriguing and biologically active metabolites
by: Antonio Dávila-Céspedes, et al.
Published: (2016-05-01)

ISOLATION, CHARACTERIZATION AND MOLECULAR IDENTIFICATION OF MYXOBACTERIA FROM TWO OUTERMOST ISLANDS OF INDONESIA
by: Siti Meliah, et al.
Published: (2018-09-01)

Bacteriophages of Myxococcus xanthus, a Social Bacterium
by: Marie Vasse, et al.
Published: (2018-07-01)

Myxobacteria of the <i>Cystobacterineae</i> Suborder Are Producers of New Vitamin K<sub>2</sub> Derived Myxoquinones
by: Fabian Panter, et al.
Published: (2022-02-01)

A Highly Polymorphic Receptor Governs Many Distinct Self-Recognition Types within the <italic toggle="yes">Myxococcales</italic> Order
by: Pengbo Cao, et al.
Published: (2019-02-01)

Hyalangiumruber sp. nov, characterization of a novel myxobacterium strain s54d21 and their secondary metabolites
by: Yi Zang, et al.
Published: (2024-03-01)

Adding Zooplankton to the OSMAC Toolkit: Effect of Grazing Stress on the Metabolic Profile and Bioactivity of a Diatom
by: Renate Døving Osvik, et al.
Published: (2021-02-01)

Antiparasitic Activities of Compounds Isolated from <i>Aspergillus fumigatus</i> Strain Discovered in Northcentral Nigeria
by: Oluwatofunmilayo A. Diyaolu, et al.
Published: (2023-01-01)

Genome Mining and Metabolic Profiling Reveal Cytotoxic Cyclodipeptides in <i>Streptomyces hygrospinosus</i> var. Beijingensis
by: Dashan Zhang, et al.
Published: (2022-10-01)

A myxobacterial GH19 lysozyme with bacteriolytic activity on both Gram-positive and negative phytopathogens
by: Yueqiu Li, et al.
Published: (2022-05-01)

Myxobacterial Response to Methyljasmonate Exposure Indicates Contribution to Plant Recruitment of Micropredators
by: Barbara I. Adaikpoh, et al.
Published: (2020-01-01)

Biocontrol Activity of Myxococcus sp. KYC 1126 against Phytophthora Blight on Hot Pepper
by: Sung Chul Yun, et al.
Published: (2011-08-01)

Induction of New Aromatic Polyketides from the Marine Actinobacterium <i>Streptomyces griseorubiginosus</i> through an OSMAC Approach
by: Víctor Rodríguez Martín-Aragón, et al.
Published: (2023-10-01)

Enhanced Molecular Networking Shows <i>Microbacterium</i> sp. V1 as a Factory of Antioxidant Proline-Rich Peptides
by: Giovanni Andrea Vitale, et al.
Published: (2023-04-01)

Cell behaviors underlying Myxococcus xanthus aggregate dispersal
by: Patrick Murphy, et al.
Published: (2023-10-01)

Editorial: Mechanisms of prokaryotic predation, volume II
by: David E. Whitworth, et al.
Published: (2023-07-01)

Emergent Myxobacterial Behaviors Arise from Reversal Suppression Induced by Kin Contacts
by: Rajesh Balagam, et al.
Published: (2021-12-01)

Suppression of predominant interfering bacteria in the purification process of myxobacteria
by: Nasim Rouhizohrab, et al.
Published: (2022-10-01)

The antibiotic crisis: How bacterial predators can help
by: Juana Pérez, et al.
Published: (2020-01-01)

Meta-16S rRNA Gene Phylogenetic Reconstruction Reveals the Astonishing Diversity of Cosmopolitan Myxobacteria
by: Yang Liu, et al.
Published: (2019-11-01)

Antibiotics from predatory bacteria
by: Juliane Korp, et al.
Published: (2016-03-01)

Editorial: Mechanisms of Prokaryotic Predation
by: David E. Whitworth, et al.
Published: (2020-09-01)

New Deoxyenhygrolides from <i>Plesiocystis pacifica</i> Provide Insights into Butenolide Core Biosynthesis
by: Joachim J. Hug, et al.
Published: (2022-01-01)

Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners
by: Nicolas A. Frank, et al.
Published: (2021-08-01)

Cryptic Metabolites from Marine-Derived Microorganisms Using OSMAC and Epigenetic Approaches
by: Cristina Pinedo-Rivilla, et al.
Published: (2022-01-01)

Marine Myxobacteria as a Source of Antibiotics—Comparison of Physiology, Polyketide-Type Genes and Antibiotic Production of Three New Isolates of Enhygromyxa salina
by: Gabriele Bierbaum, et al.
Published: (2010-09-01)

Rapid Discovery of Substances with Anticancer Potential from Marine Fungi Based on a One Strain–Many Compounds Strategy and UPLC-QTOF-MS
by: Yu-Ting Wu, et al.
Published: (2023-12-01)