Effects of Mindfulness-Based Interventions on Depression in Patients With Breast Cancer: A Systematic Review and Meta-Analysis
Objective: We examined the effects of Mindfulness-based interventions (MBIs) on depressive symptoms in women with breast cancer and examined the moderating effects of participant characteristics, research methodologies, and features of interventions. Methods: We systematically searched 12 databases...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2023-12-01
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| Series: | Integrative Cancer Therapies |
| Online Access: | https://doi.org/10.1177/15347354231220617 |
| _version_ | 1797378125640761344 |
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| author | Chuntana Reangsing PhD, RN Sasinun Punsuwun PhD, RN Kristine Keller PhD, RN |
| author_facet | Chuntana Reangsing PhD, RN Sasinun Punsuwun PhD, RN Kristine Keller PhD, RN |
| author_sort | Chuntana Reangsing PhD, RN |
| collection | DOAJ |
| description | Objective: We examined the effects of Mindfulness-based interventions (MBIs) on depressive symptoms in women with breast cancer and examined the moderating effects of participant characteristics, research methodologies, and features of interventions. Methods: We systematically searched 12 databases through November 2022 without date restrictions using the following search terms: (mindful* or meditation) AND (cancer OR neoplasm) AND (depress*). Studies included were primary studies evaluating MBIs in women with breast cancer who also had depression. Studies were included if they used a control group and were written in English. We used a random-effects model to compute effect sizes (ESs) using Hedges’ g, forest plot, and Q and I 2 statistics as measure of heterogeneity. We also requested moderator analyses. Results: We found 19 studies with 2139 participants (49.4 ± 8.3 years old) that met inclusion criteria for this meta-analysis and systematic review. Overall, women in MBI groups demonstrated significantly lower levels of depression ( g = 0.48, 95% CI:0.159, 0.792, P < .001) compared to women in control groups. Regarding moderators, providing MBIs with a home assignment component showed a significantly greater effect on decreasing depressive symptoms ( g = 1.75) compared to MBIs without a home assignment component ( g = 0.20). When researchers used concealed allocation technique, the interventions demonstrated lower effects on depression than when concealed allocation ( g = 0.11vs g = 1.33, P ≤ .001) was not reported. Additionally, when researchers reported high rates of sample attrition, they found a lower effect size on depression (β = −.019, Q = 3.97, P = .046) indicating that attrition moderates the effect. Conclusion: MBIs are moderately effective interventions to reduce depressive symptoms among women with breast cancer. Clinicians might consider encouraging MBIs as adjunct/alternative treatments for women with breast cancer to manage symptoms of depression. Interventions that incorporat home assignments for practicing mindfulness are likely to have a greater effect on reducing depressive symptoms. Additionally, methods including concealed allocation and attrition rate were moderators of the effects of MBIs on depression in women with breast cancer. |
| first_indexed | 2024-03-08T20:02:16Z |
| format | Article |
| id | doaj.art-997349cfef784a98b365958626a0365f |
| institution | Directory Open Access Journal |
| issn | 1552-695X |
| language | English |
| last_indexed | 2024-03-08T20:02:16Z |
| publishDate | 2023-12-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Integrative Cancer Therapies |
| spelling | doaj.art-997349cfef784a98b365958626a0365f2023-12-23T16:03:19ZengSAGE PublishingIntegrative Cancer Therapies1552-695X2023-12-012210.1177/15347354231220617Effects of Mindfulness-Based Interventions on Depression in Patients With Breast Cancer: A Systematic Review and Meta-AnalysisChuntana Reangsing PhD, RN0Sasinun Punsuwun PhD, RN1Kristine Keller PhD, RN2Nursing Innovation Research and Resource Unit, Mae Fah Luaung University, ThailandUniversity of Phayao, Phayao, ThailandSaint Louis University, Saint Louis, MO, USAObjective: We examined the effects of Mindfulness-based interventions (MBIs) on depressive symptoms in women with breast cancer and examined the moderating effects of participant characteristics, research methodologies, and features of interventions. Methods: We systematically searched 12 databases through November 2022 without date restrictions using the following search terms: (mindful* or meditation) AND (cancer OR neoplasm) AND (depress*). Studies included were primary studies evaluating MBIs in women with breast cancer who also had depression. Studies were included if they used a control group and were written in English. We used a random-effects model to compute effect sizes (ESs) using Hedges’ g, forest plot, and Q and I 2 statistics as measure of heterogeneity. We also requested moderator analyses. Results: We found 19 studies with 2139 participants (49.4 ± 8.3 years old) that met inclusion criteria for this meta-analysis and systematic review. Overall, women in MBI groups demonstrated significantly lower levels of depression ( g = 0.48, 95% CI:0.159, 0.792, P < .001) compared to women in control groups. Regarding moderators, providing MBIs with a home assignment component showed a significantly greater effect on decreasing depressive symptoms ( g = 1.75) compared to MBIs without a home assignment component ( g = 0.20). When researchers used concealed allocation technique, the interventions demonstrated lower effects on depression than when concealed allocation ( g = 0.11vs g = 1.33, P ≤ .001) was not reported. Additionally, when researchers reported high rates of sample attrition, they found a lower effect size on depression (β = −.019, Q = 3.97, P = .046) indicating that attrition moderates the effect. Conclusion: MBIs are moderately effective interventions to reduce depressive symptoms among women with breast cancer. Clinicians might consider encouraging MBIs as adjunct/alternative treatments for women with breast cancer to manage symptoms of depression. Interventions that incorporat home assignments for practicing mindfulness are likely to have a greater effect on reducing depressive symptoms. Additionally, methods including concealed allocation and attrition rate were moderators of the effects of MBIs on depression in women with breast cancer.https://doi.org/10.1177/15347354231220617 |
| spellingShingle | Chuntana Reangsing PhD, RN Sasinun Punsuwun PhD, RN Kristine Keller PhD, RN Effects of Mindfulness-Based Interventions on Depression in Patients With Breast Cancer: A Systematic Review and Meta-Analysis Integrative Cancer Therapies |
| title | Effects of Mindfulness-Based Interventions on Depression in Patients With Breast Cancer: A Systematic Review and Meta-Analysis |
| title_full | Effects of Mindfulness-Based Interventions on Depression in Patients With Breast Cancer: A Systematic Review and Meta-Analysis |
| title_fullStr | Effects of Mindfulness-Based Interventions on Depression in Patients With Breast Cancer: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Effects of Mindfulness-Based Interventions on Depression in Patients With Breast Cancer: A Systematic Review and Meta-Analysis |
| title_short | Effects of Mindfulness-Based Interventions on Depression in Patients With Breast Cancer: A Systematic Review and Meta-Analysis |
| title_sort | effects of mindfulness based interventions on depression in patients with breast cancer a systematic review and meta analysis |
| url | https://doi.org/10.1177/15347354231220617 |
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