Synthesis of New Derivatives of P­ Lactam Antibiotics

New    Derivatives    for   Known    P-   Jactam  antibiotics   were synthesized  utilizing  the  free  amino  group  pres nt  in  the  parent compounds as the site for derivatization. The objectives for this study are to have new compounds which could have an increased potential resistance t...

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Main Authors: M.D. Saud, N.F. AL- Mejwel, A. K. Sbarrad
Format: Article
Language:English
Published: University of Baghdad 2017-09-01
Series:Ibn Al-Haitham Journal for Pure and Applied Sciences
Online Access:https://jih.uobaghdad.edu.iq/index.php/j/article/view/1345
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author M.D. Saud
N.F. AL- Mejwel
A. K. Sbarrad
author_facet M.D. Saud
N.F. AL- Mejwel
A. K. Sbarrad
author_sort M.D. Saud
collection DOAJ
description New    Derivatives    for   Known    P-   Jactam  antibiotics   were synthesized  utilizing  the  free  amino  group  pres nt  in  the  parent compounds as the site for derivatization. The objectives for this study are to have new compounds which could have an increased potential resistance to the degradative enzymes knowing to be able to destroy the antibacterial activity of 13· lactam antibiotics- Besides. these new derivatives  could  be  congeners  of     known  agents,  or  may  be  a pott:ntial pro-drugs for these agents.
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spelling doaj.art-997439a313d54ec8a291fa48993ac6792022-12-22T00:41:15ZengUniversity of BaghdadIbn Al-Haitham Journal for Pure and Applied Sciences1609-40422521-34072017-09-01212Synthesis of New Derivatives of P­ Lactam AntibioticsM.D. SaudN.F. AL- MejwelA. K. Sbarrad New    Derivatives    for   Known    P-   Jactam  antibiotics   were synthesized  utilizing  the  free  amino  group  pres nt  in  the  parent compounds as the site for derivatization. The objectives for this study are to have new compounds which could have an increased potential resistance to the degradative enzymes knowing to be able to destroy the antibacterial activity of 13· lactam antibiotics- Besides. these new derivatives  could  be  congeners  of     known  agents,  or  may  be  a pott:ntial pro-drugs for these agents. https://jih.uobaghdad.edu.iq/index.php/j/article/view/1345
spellingShingle M.D. Saud
N.F. AL- Mejwel
A. K. Sbarrad
Synthesis of New Derivatives of P­ Lactam Antibiotics
Ibn Al-Haitham Journal for Pure and Applied Sciences
title Synthesis of New Derivatives of P­ Lactam Antibiotics
title_full Synthesis of New Derivatives of P­ Lactam Antibiotics
title_fullStr Synthesis of New Derivatives of P­ Lactam Antibiotics
title_full_unstemmed Synthesis of New Derivatives of P­ Lactam Antibiotics
title_short Synthesis of New Derivatives of P­ Lactam Antibiotics
title_sort synthesis of new derivatives of pa lactam antibiotics
url https://jih.uobaghdad.edu.iq/index.php/j/article/view/1345
work_keys_str_mv AT mdsaud synthesisofnewderivativesofpalactamantibiotics
AT nfalmejwel synthesisofnewderivativesofpalactamantibiotics
AT aksbarrad synthesisofnewderivativesofpalactamantibiotics