The Genetic Diversity of Mink (<i>Neovison vison</i>) Populations in China
The American mink (<i>Neovison vison</i>) is a semiaquatic species of Mustelid native to North America that is now widespread in China. However, the knowledge of genetic diversity of mink in China is still limited. In this study, we investigated the genetic diversity and identified signi...
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MDPI AG
2023-04-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/13/9/1497 |
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| author | Tietao Zhang Hu Li Peter Foged Larsen Hengxing Ba Hongyu Shi Haihua Zhang Zongyue Liu |
| author_facet | Tietao Zhang Hu Li Peter Foged Larsen Hengxing Ba Hongyu Shi Haihua Zhang Zongyue Liu |
| author_sort | Tietao Zhang |
| collection | DOAJ |
| description | The American mink (<i>Neovison vison</i>) is a semiaquatic species of Mustelid native to North America that is now widespread in China. However, the knowledge of genetic diversity of mink in China is still limited. In this study, we investigated the genetic diversity and identified significant single nucleotide polymorphisms (SNPs) in mink populations of five different color types in three different mink farms in China. Using double-digest restriction site-associated DNA sequencing, we identified a total of 1.3 million SNPs. After filtering the SNPs, phylogenetic tree, Fst, principal component, and population structure analyses were performed. The results demonstrated that red mink and black mink grouped, with separate clustering of all other color types. The population divergence index (Fst) study confirmed that different mink populations were distinct (K = 4). Two populations with different coat colors were subjected to the selection signature analysis, and 2300 genes were found to have a clear selection signature. The genes with a selection signature were subjected to Gene Ontology (GO) categorization and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis, the results revealed that the genes with a selection signature were enriched in the melanogenesis pathway. These study’s findings have set the stage for improved breeding and conservation of genetic resources in real-world practical mink farming. |
| first_indexed | 2024-03-11T04:25:19Z |
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| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-11T04:25:19Z |
| publishDate | 2023-04-01 |
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| series | Animals |
| spelling | doaj.art-9975faec3e1e427096fe2a22cfa9d6232023-11-17T22:29:55ZengMDPI AGAnimals2076-26152023-04-01139149710.3390/ani13091497The Genetic Diversity of Mink (<i>Neovison vison</i>) Populations in ChinaTietao Zhang0Hu Li1Peter Foged Larsen2Hengxing Ba3Hongyu Shi4Haihua Zhang5Zongyue Liu6Jilin Provincial Key Laboratory for Molecular Biology of Special Economic Animals, Key Laboratory of Special Economic Animal Genetic Breeding and Reproduction, Ministry of Agriculture, Institute of Special Economic Animal and Plant Sciences, The Chinese Academy of Agricultural Sciences, Changchun 130112, ChinaJilin Provincial Key Laboratory for Molecular Biology of Special Economic Animals, Key Laboratory of Special Economic Animal Genetic Breeding and Reproduction, Ministry of Agriculture, Institute of Special Economic Animal and Plant Sciences, The Chinese Academy of Agricultural Sciences, Changchun 130112, ChinaJilin Provincial Key Laboratory for Molecular Biology of Special Economic Animals, Key Laboratory of Special Economic Animal Genetic Breeding and Reproduction, Ministry of Agriculture, Institute of Special Economic Animal and Plant Sciences, The Chinese Academy of Agricultural Sciences, Changchun 130112, ChinaInstitute of Antler Science and Product Technology, Changchun Sci-Tech University, Changchun 130112, ChinaJilin Provincial Key Laboratory for Molecular Biology of Special Economic Animals, Key Laboratory of Special Economic Animal Genetic Breeding and Reproduction, Ministry of Agriculture, Institute of Special Economic Animal and Plant Sciences, The Chinese Academy of Agricultural Sciences, Changchun 130112, ChinaColleges of Animal Science, Hebei Normal University of Science and Technology, Qinhuangdao 066004, ChinaJilin Provincial Key Laboratory for Molecular Biology of Special Economic Animals, Key Laboratory of Special Economic Animal Genetic Breeding and Reproduction, Ministry of Agriculture, Institute of Special Economic Animal and Plant Sciences, The Chinese Academy of Agricultural Sciences, Changchun 130112, ChinaThe American mink (<i>Neovison vison</i>) is a semiaquatic species of Mustelid native to North America that is now widespread in China. However, the knowledge of genetic diversity of mink in China is still limited. In this study, we investigated the genetic diversity and identified significant single nucleotide polymorphisms (SNPs) in mink populations of five different color types in three different mink farms in China. Using double-digest restriction site-associated DNA sequencing, we identified a total of 1.3 million SNPs. After filtering the SNPs, phylogenetic tree, Fst, principal component, and population structure analyses were performed. The results demonstrated that red mink and black mink grouped, with separate clustering of all other color types. The population divergence index (Fst) study confirmed that different mink populations were distinct (K = 4). Two populations with different coat colors were subjected to the selection signature analysis, and 2300 genes were found to have a clear selection signature. The genes with a selection signature were subjected to Gene Ontology (GO) categorization and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis, the results revealed that the genes with a selection signature were enriched in the melanogenesis pathway. These study’s findings have set the stage for improved breeding and conservation of genetic resources in real-world practical mink farming.https://www.mdpi.com/2076-2615/13/9/1497minkgenetic diversitypopulation structureselective sweepsdd-RAD |
| spellingShingle | Tietao Zhang Hu Li Peter Foged Larsen Hengxing Ba Hongyu Shi Haihua Zhang Zongyue Liu The Genetic Diversity of Mink (<i>Neovison vison</i>) Populations in China Animals mink genetic diversity population structure selective sweeps dd-RAD |
| title | The Genetic Diversity of Mink (<i>Neovison vison</i>) Populations in China |
| title_full | The Genetic Diversity of Mink (<i>Neovison vison</i>) Populations in China |
| title_fullStr | The Genetic Diversity of Mink (<i>Neovison vison</i>) Populations in China |
| title_full_unstemmed | The Genetic Diversity of Mink (<i>Neovison vison</i>) Populations in China |
| title_short | The Genetic Diversity of Mink (<i>Neovison vison</i>) Populations in China |
| title_sort | genetic diversity of mink i neovison vison i populations in china |
| topic | mink genetic diversity population structure selective sweeps dd-RAD |
| url | https://www.mdpi.com/2076-2615/13/9/1497 |
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