Emerging PCR-Based Techniques to Study HIV-1 Reservoir Persistence

Emerging PCR-Based Techniques to Study HIV-1 Reservoir Persistence

While current antiretroviral therapies are able to halt HIV-1 progression, they are not curative, as an interruption of treatment usually leads to viral rebound. The persistence of this stable HIV-1 latent reservoir forms the major barrier in HIV-1 cure research. The need for a better understanding...

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Bibliographic Details
Main Authors: Laurens Lambrechts, Basiel Cole, Sofie Rutsaert, Wim Trypsteen, Linos Vandekerckhove
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Viruses
Subjects:
hiv-1
hiv-1 reservoir
pcr
sequencing
ngs
replication-competent
integration site
hiv-1 genome
Online Access:https://www.mdpi.com/1999-4915/12/2/149

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