MUC1: Structure, Function, and Clinic Application in Epithelial Cancers
The transmembrane glycoprotein mucin 1 (MUC1) is a mucin family member that has different functions in normal and cancer cells. Owing to its structural and biochemical properties, MUC1 can act as a lubricant, moisturizer, and physical barrier in normal cells. However, in cancer cells, MUC1 often und...
Main Authors: | Wenqing Chen, Zhu Zhang, Shiqing Zhang, Peili Zhu, Joshua Ka-Shun Ko, Ken Kin-Lam Yung |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-06-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/12/6567 |
Similar Items
-
Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas
by: Onur Oral, et al.
Published: (2020-01-01) -
MUC1 modulates gastric epithelial immune response to bacteria or inflammatory stimuli
by: Shofyatul Y. Triyana, et al.
Published: (2015-12-01) -
Prognostic significance of muc4 expression in gallbladder carcinoma
by: Lee Hyeon, et al.
Published: (2012-10-01) -
MUC1 and MUC16: critical for immune modulation in cancer therapeutics
by: Xinyi Chen, et al.
Published: (2024-02-01) -
Emergence of <i>MUC1</i> in Mammals for Adaptation of Barrier Epithelia
by: Donald W. Kufe
Published: (2022-09-01)