Clinicopathologic and Molecular Analysis of Inflammatory Pseudotumor-Like Follicular/Fibroblastic Dendritic Cell Sarcoma: A Case Report and Review of Literature
Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell (FDC/FRC) sarcoma is an extremely rare neoplasm of the spleen associated with EBV and characterized by spindle cell morphology, dense mixed chronic inflammatory background, and a broad immunophenotypic profile often causing a diagn...
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| Format: | Article |
| Language: | English |
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Federation of Turkish Pathology Societies
2021-09-01
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| Series: | Türk Patoloji Dergisi |
| Subjects: | |
| Online Access: |
http://www.turkjpath.org/pdf.php3?id=1960
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| _version_ | 1828029115447377920 |
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| author | Bryan MORALES-VARGAS Kristin DEEB Deniz PEKER |
| author_facet | Bryan MORALES-VARGAS Kristin DEEB Deniz PEKER |
| author_sort | Bryan MORALES-VARGAS |
| collection | DOAJ |
| description | Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell (FDC/FRC) sarcoma is an extremely rare neoplasm of the spleen associated with EBV and characterized by spindle cell morphology, dense mixed chronic inflammatory background, and a broad immunophenotypic profile often causing a diagnostic challenge for pathologists. The molecular features of FDC/FRC sarcoma are largely unknown due to a lack of comprehensive data. Here we present the results of next-generation sequencing and Single Nucleotide Polymorphism Copy Number array analysis in a case of FDC/FRC and review the literature. |
| first_indexed | 2024-04-10T14:05:50Z |
| format | Article |
| id | doaj.art-997b24aed73a473497933b7eecf01445 |
| institution | Directory Open Access Journal |
| issn | 1018-5615 1309-5730 |
| language | English |
| last_indexed | 2024-04-10T14:05:50Z |
| publishDate | 2021-09-01 |
| publisher | Federation of Turkish Pathology Societies |
| record_format | Article |
| series | Türk Patoloji Dergisi |
| spelling | doaj.art-997b24aed73a473497933b7eecf014452023-02-15T16:10:03ZengFederation of Turkish Pathology SocietiesTürk Patoloji Dergisi1018-56151309-57302021-09-0137326627210.5146/tjpath.2021.01523Clinicopathologic and Molecular Analysis of Inflammatory Pseudotumor-Like Follicular/Fibroblastic Dendritic Cell Sarcoma: A Case Report and Review of LiteratureBryan MORALES-VARGASKristin DEEBDeniz PEKERInflammatory pseudotumor-like follicular/fibroblastic dendritic cell (FDC/FRC) sarcoma is an extremely rare neoplasm of the spleen associated with EBV and characterized by spindle cell morphology, dense mixed chronic inflammatory background, and a broad immunophenotypic profile often causing a diagnostic challenge for pathologists. The molecular features of FDC/FRC sarcoma are largely unknown due to a lack of comprehensive data. Here we present the results of next-generation sequencing and Single Nucleotide Polymorphism Copy Number array analysis in a case of FDC/FRC and review the literature. http://www.turkjpath.org/pdf.php3?id=1960 inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcomasplenic tumorbcor1l1jak2 |
| spellingShingle | Bryan MORALES-VARGAS Kristin DEEB Deniz PEKER Clinicopathologic and Molecular Analysis of Inflammatory Pseudotumor-Like Follicular/Fibroblastic Dendritic Cell Sarcoma: A Case Report and Review of Literature Türk Patoloji Dergisi inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma splenic tumor bcor1l1 jak2 |
| title | Clinicopathologic and Molecular Analysis of Inflammatory Pseudotumor-Like Follicular/Fibroblastic Dendritic Cell Sarcoma: A Case Report and Review of Literature |
| title_full | Clinicopathologic and Molecular Analysis of Inflammatory Pseudotumor-Like Follicular/Fibroblastic Dendritic Cell Sarcoma: A Case Report and Review of Literature |
| title_fullStr | Clinicopathologic and Molecular Analysis of Inflammatory Pseudotumor-Like Follicular/Fibroblastic Dendritic Cell Sarcoma: A Case Report and Review of Literature |
| title_full_unstemmed | Clinicopathologic and Molecular Analysis of Inflammatory Pseudotumor-Like Follicular/Fibroblastic Dendritic Cell Sarcoma: A Case Report and Review of Literature |
| title_short | Clinicopathologic and Molecular Analysis of Inflammatory Pseudotumor-Like Follicular/Fibroblastic Dendritic Cell Sarcoma: A Case Report and Review of Literature |
| title_sort | clinicopathologic and molecular analysis of inflammatory pseudotumor like follicular fibroblastic dendritic cell sarcoma a case report and review of literature |
| topic | inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma splenic tumor bcor1l1 jak2 |
| url |
http://www.turkjpath.org/pdf.php3?id=1960
|
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