Evaluation of Hospital Antimicrobial Stewardship Programs: Implementation, Process, Impact, and Outcomes, Review of Systematic Reviews
Antimicrobial Stewardship Programs (ASP) were introduced in healthcare as a public health priority to promote appropriate prescribing of antimicrobials, to reduce adverse events related to antimicrobials, as well as to control the escalating challenges of antimicrobial resistance. To deliver aimed o...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-03-01
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| Series: | Antibiotics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6382/13/3/253 |
| _version_ | 1827307301257609216 |
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| author | Hamad Abdel Hadi Faiha Eltayeb Sara Al Balushi Joanne Daghfal Faraz Ahmed Ceu Mateus |
| author_facet | Hamad Abdel Hadi Faiha Eltayeb Sara Al Balushi Joanne Daghfal Faraz Ahmed Ceu Mateus |
| author_sort | Hamad Abdel Hadi |
| collection | DOAJ |
| description | Antimicrobial Stewardship Programs (ASP) were introduced in healthcare as a public health priority to promote appropriate prescribing of antimicrobials, to reduce adverse events related to antimicrobials, as well as to control the escalating challenges of antimicrobial resistance. To deliver aimed outcome objectives, ASPs involve multiple connected implementation process measures. A systematic review was conducted to evaluate both concepts of ASPs. Guided by PRISMA frames, published systematic reviews (SR) focusing on ASPs restricted to secondary and tertiary healthcare were evaluated over the past 10 years involving all age groups. Out of 265 identified SR studies, 63 met the inclusion criteria. The majority were conducted in Europe and North America, with limited studies from other regions. In the reviewed studies, all age groups were examined, although they were conducted mainly on adults when compared to children and infants. Both process and outcomes measures of ASPs were examined equally and simultaneously through 25 different concepts, dominated by efficacy, antimicrobial resistance, and economic impact, while information technology as well as role of pharmacy and behavioral factors were equally examined. The main broad conclusions from the review were that, across the globe, ASPs demonstrated effectiveness, proved efficacy, and confirmed efficiency, while focused evaluation advocated that developed countries should target medium- and small-sized hospitals while developing countries should continue rolling ASPs across healthcare facilities. Additionally, the future of ASPs should focus on embracing evolving information technology to bridge the gaps in knowledge, skills, and attitude, as well as to enhance appropriate decision making. |
| first_indexed | 2024-04-24T18:36:54Z |
| format | Article |
| id | doaj.art-997f89737a6447c992b7c0aaa69da966 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-04-24T18:36:54Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-997f89737a6447c992b7c0aaa69da9662024-03-27T13:18:12ZengMDPI AGAntibiotics2079-63822024-03-0113325310.3390/antibiotics13030253Evaluation of Hospital Antimicrobial Stewardship Programs: Implementation, Process, Impact, and Outcomes, Review of Systematic ReviewsHamad Abdel Hadi0Faiha Eltayeb1Sara Al Balushi2Joanne Daghfal3Faraz Ahmed4Ceu Mateus5Communicable Diseases Centre, Hamad Medical Corporation, Doha P.O. Box 3050, QatarDivision of Microbiology, Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha P.O. Box 3050, QatarCommunicable Diseases Centre, Hamad Medical Corporation, Doha P.O. Box 3050, QatarCommunicable Diseases Centre, Hamad Medical Corporation, Doha P.O. Box 3050, QatarDivision of Health Research, Faculty of Health and Medicine, Lancaster University, Lancaster LA1 4YW, UKDivision of Health Research, Faculty of Health and Medicine, Lancaster University, Lancaster LA1 4YW, UKAntimicrobial Stewardship Programs (ASP) were introduced in healthcare as a public health priority to promote appropriate prescribing of antimicrobials, to reduce adverse events related to antimicrobials, as well as to control the escalating challenges of antimicrobial resistance. To deliver aimed outcome objectives, ASPs involve multiple connected implementation process measures. A systematic review was conducted to evaluate both concepts of ASPs. Guided by PRISMA frames, published systematic reviews (SR) focusing on ASPs restricted to secondary and tertiary healthcare were evaluated over the past 10 years involving all age groups. Out of 265 identified SR studies, 63 met the inclusion criteria. The majority were conducted in Europe and North America, with limited studies from other regions. In the reviewed studies, all age groups were examined, although they were conducted mainly on adults when compared to children and infants. Both process and outcomes measures of ASPs were examined equally and simultaneously through 25 different concepts, dominated by efficacy, antimicrobial resistance, and economic impact, while information technology as well as role of pharmacy and behavioral factors were equally examined. The main broad conclusions from the review were that, across the globe, ASPs demonstrated effectiveness, proved efficacy, and confirmed efficiency, while focused evaluation advocated that developed countries should target medium- and small-sized hospitals while developing countries should continue rolling ASPs across healthcare facilities. Additionally, the future of ASPs should focus on embracing evolving information technology to bridge the gaps in knowledge, skills, and attitude, as well as to enhance appropriate decision making.https://www.mdpi.com/2079-6382/13/3/253Antimicrobial Stewardship Programs (ASP/AMSP)antimicrobial consumptionantimicrobial resistance |
| spellingShingle | Hamad Abdel Hadi Faiha Eltayeb Sara Al Balushi Joanne Daghfal Faraz Ahmed Ceu Mateus Evaluation of Hospital Antimicrobial Stewardship Programs: Implementation, Process, Impact, and Outcomes, Review of Systematic Reviews Antibiotics Antimicrobial Stewardship Programs (ASP/AMSP) antimicrobial consumption antimicrobial resistance |
| title | Evaluation of Hospital Antimicrobial Stewardship Programs: Implementation, Process, Impact, and Outcomes, Review of Systematic Reviews |
| title_full | Evaluation of Hospital Antimicrobial Stewardship Programs: Implementation, Process, Impact, and Outcomes, Review of Systematic Reviews |
| title_fullStr | Evaluation of Hospital Antimicrobial Stewardship Programs: Implementation, Process, Impact, and Outcomes, Review of Systematic Reviews |
| title_full_unstemmed | Evaluation of Hospital Antimicrobial Stewardship Programs: Implementation, Process, Impact, and Outcomes, Review of Systematic Reviews |
| title_short | Evaluation of Hospital Antimicrobial Stewardship Programs: Implementation, Process, Impact, and Outcomes, Review of Systematic Reviews |
| title_sort | evaluation of hospital antimicrobial stewardship programs implementation process impact and outcomes review of systematic reviews |
| topic | Antimicrobial Stewardship Programs (ASP/AMSP) antimicrobial consumption antimicrobial resistance |
| url | https://www.mdpi.com/2079-6382/13/3/253 |
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